Return to main results Retrieve Phyre Job Id

Job DescriptionP31441
Confidence100.00%DateThu Jan 5 11:47:32 GMT 2012
Rank12Aligned Residues361
% Identity16%Templatec2vr2A_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: human dihydropyrimidinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   32.......40.........50.........60.........70.........80.........90........ .100.....
Predicted Secondary structure 



































......
Query SS confidence 


































































. . . . . .






Query Sequence  YIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYTDAPALQRIDARGATAVPGFIDAHLHIESSMM. . . . . . TPVTFET
Query Conservation 





 



    
   

 
 



  

          



 
  
 




 
 


 
  ......

   
 
Alig confidence 












..
















.......



























......






Template Conservation 


 

 
 
   ..     
 
  


  

.......   


  
  
 




 
 

                  
Template Sequence  LLIRGGRVVNDDF. . SEVADVLVEDGVVRALG. . . . . . . HLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTK
Template Known Secondary structure  S

SS
..
TT.......


TTS

TT
B
SSSB
S

TT
Template Predicted Secondary structure 





..



.......






















Template SS confidence 















































































   7..10......... 20.........30...... ...40.........50.........60.........70.......
 
   106...110.........120.........130.........140.........150.........160.........170.........180.....
Predicted Secondary structure 











































Query SS confidence 















































































Query Sequence  ATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQVTGLAE
Query Conservation    
  





 
  
 
 
 
  

   
               
  
     
                   
  
 
Alig confidence 




















































........


















Template Conservation       




 
                                         ........            
      
Template Sequence  AALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQ. . . . . . . . VKEEMKILVQDKGVNSFKM
Template Known Secondary structure  TTT


TT

TTT
SS
S
S........TS


Template Predicted Secondary structure 
























........



Template SS confidence 















































































   8990.........100.........110.........120.........130.........140. ........150.........160
 
   186...190.........200... ......210....... ..220.......
Predicted Secondary structure 








...




...................................

Query SS confidence 

















. . .













. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .









Query Sequence  MMDYPGVISGQNALLDKL. . . DAFRHLTLDGHCPG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LGGKELNAYI
Query Conservation 
     
       
  
...
      
 

   ...................................     
    
Alig confidence 

















...













...................................









Template Conservation                       
                                                      
   
Template Sequence  FMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV
Template Known Secondary structure  SSSTTTTB

T

S
TT

STTS
Template Predicted Secondary structure 

































Template SS confidence 















































































   161........170.........180.........190.........200.........210.........220.........230.........240
 
   228.230........ .240.........250..... ....260.........270........
Predicted Secondary structure 





..



...........................












Query SS confidence 










. .
















. . . . . . . . . . . . . . . . . . . . . . . . . . .






















Query Sequence  TAGIENCHESY. . QLEEGRRKLQLGMSLMI. . . . . . . . . . . . . . . . . . . . . . . . . . . REGSAARNLNALAPLINEFNSPQ
Query Conservation    

   
   ..   
  
 
  
  
  ...........................   
       
   
       
Alig confidence 










..
















...........................






















Template Conservation         
                                                  
                  
  
Template Sequence  NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDL
Template Known Secondary structure  T



TT

B

SGGGG
SSTT

SS


S
TTTTSS
Template Predicted Secondary structure 

























Template SS confidence 















































































   241........250.........260.........270.........280.........290.........300.........310.........320
 
   279280...... ...290.........300.........310.........320.........330.. .......340
Predicted Secondary structure 


.................



















.







Query SS confidence 







. . . . . . . . . . . . . . . . .













































.







Query Sequence  CMLCTDDR. . . . . . . . . . . . . . . . . NPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHL. GLLAPGKQ
Query Conservation 
 
 

  .................    
   
 
   

 

  
  
   

  

 


  


 
 .






 
Alig confidence 







.................













































.







Template Conservation 
 



                     
                    

  


   
   
  

     


  

 
Template Sequence  TTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSD
Template Known Secondary structure 


B

B



GGGSS
GGGS


B

TTTTTTTSS
TTT
TTTSS

STTSB
Template Predicted Secondary structure 


































Template SS confidence 















































































   321........330.........340.........350.........360.........370.........380.........390.........400
 
   341...... ..350... ......360.........370.........380.........390.......
Predicted Secondary structure 


.......





................






























Query SS confidence 






. . . . . . .





. . . . . . . . . . . . . . . .











































Query Sequence  ADIVLLS. . . . . . . DARKVT. . . . . . . . . . . . . . . . VQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQPVSASD
Query Conservation 






....... 
    ................
  
   
  
   
                            
Alig confidence 






.......





................











































Template Conservation 






      
               
      
  


 



  

        
                    
Template Sequence  ADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD
Template Known Secondary structure 



TTT
SSS
S

TTTT
TTTT


TT
S
B



SS
Template Predicted Secondary structure 






























Template SS confidence 















































































   401........410.........420.........430.........440.........450.........460.........470.........480
 
   398.400.........
Predicted Secondary structure 




Query SS confidence 











Query Sequence  FALQFTPGKRYR
Query Conservation              
Alig confidence 











Template Conservation              
Template Sequence  RTCTPTPVERAP
Template Known Secondary structure  SS







Template Predicted Secondary structure 









Template SS confidence 











   481........490..
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions