|   |
14 | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
. | . | . | . | . | 70 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |  | . |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
D | C | W | G | D | L | P | W | G | K | L | Y | R | K | A | L | E | R | Q | L | N | P | W | F | . |
. |
. |
. |
. |
. |
T | K | M | Y | G | F | H | L | L | K | I | G | N | L | S | A | E | I | N | C | E | A | C | A | V | S | H | . |
Q | V | N | V | S | A | Q | G | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |
|   |   |
|
|   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
| . | . | . | . | . | . |   |   |   |   |
|   |   |   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
A | T | Y | Y | S | F | D | G | S | P | S | P | E | A | E | M | L | K | F | N | L | E | C | L | H | K | T | F | G | P | G | G | L | Q | G | D | T | L | I | D | I | G | S | G | P | T | I | Y | Q | V | L | A | A | C | D | S | F | Q | D | I | T | L | S | D | F | T | D | R | N | R | E | E | L | E | K | W | L | K | K | E |
Template Known Secondary structure |   |
 |  |  |
|
|
|
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T | S |
|
|  |  |  |  |  |  | S | S |
| T | T |
|
| G | G | G | T | T | G | G | G | T |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
22 | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
74 | . | . | . | . | . | 80 | . | . | . | |
|
|
|
. | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | |
|
|
|
. | . | . | . | . | . | 110 | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |
|  |  |  | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | V | Q | V | Q | A | D | P | L | H | . |
. |
. |
. |
L | P | F | A | D | K | S | V | D | V | C | L | L | A | H | T | L | P | W | C | . |
. |
. |
. |
T | D | P | H | R | L | L | R |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   | . | . | . | . |
|
|   |   |   |   |
|   |
|   |
|   |   |   |   |   |
|   |   |   | . | . | . | . |   |   |
|   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
P | G | A | Y | D | W | T | P | A | V | K | F | A | C | E | L | E | G | N | S | G | R | W | E | E | K | E | E | K | L | R | A | A | V | K | R | V | L | K | C | D | V | H | L | G | N | P | L | A | P | A | V | L | P | L | A | D | C | V | L | T | L | L | A | M | E | C | A | C | C | S | L | D | A | Y | R | A | A | L | C |
Template Known Secondary structure |   |
T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T | S | S | S | T | T | T | T |
|
|
|
|
|  |  |  |  |  |  |  | S |
|  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
102 | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . |
  |
  |   |
112 | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | D | R | V | L | I | D | D | G | W | L | V | I | S | G | F | N | P | I | S | F | M | G | L | R | K | L | V | P | V | L | R | K | T | S | P | Y | N | S | R | M | F | T | L | M | R | Q | L | D | W | L | S | L | L | N | F | E | V | L | H | A | S | R | F | H | V | L | P | W | N | K | H | G | G | K | L | L | N | A |
Query Conservation |   |
|   |   |
|
|
|   |
|
|
|   |
|   |
|   |   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |
Template Sequence |   |
N | L | A | S | L | L | K | P | G | G | H | L | V | T | T | V | T | L | R | L | P | S | Y | . |
. |
. |
. |
. |
. |
. |
. |
M | V | G | K | R | E | F | S | C | V | A | L | E | K | G | E | V | E | Q | A | V | L | D | A | G | F | D | I | E | Q | L | L | H | S | P | Q | S | Y | S | V | T | N | A | A | . |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
|  |  | . | . | . | . | . | . | . | . |  |  | T | T |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |
|
|
|
|
| T | T | T |
|
| . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
182 | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | |
|
|
|
|
  |
  |   |
192 | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | I | P | A | L | G | C | L | Q | L | I | V | A | R | K | R |
Query Conservation |   |
  |   |
|   |   |
|   |   |
|   |
|   |
|   |
|
|
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |   |
|
|
|   |
Template Sequence |   |
. |
. |
. |
. |
N | N | G | V | C | C | I | V | A | R | K | K |
Template Known Secondary structure |   |
. | . | . | . |
|
|
|  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
. | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
249 | 250 | . | . | . | . | . | . | . | . | . | 260 |
  |