|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | |
. | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
|
|
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | T | M | N | V | L | I | C | Q | Q | P | K | . |
E | L | V | W | K | Q | R | E | I | P | I | P | G | D | N | E | A | L | I | K | I | K | S | V | G | I | C | G | T | D | I | H | A | W | G | G | N | Q | . |
. |
. |
P | F | F | S | Y | P | R | V | L | G | H | E | I | C | G | E | I | V | G | L | G | K | N | I | A | D |
Query Conservation |   |
  |
|
|
|
|   |
|   |   |   |
|   | . |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|   |
|
|
|   |   |
|   |   |   |   |   |
|   |   | . | . | . |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |
|
|   |
|
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |
|   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |
Template Sequence |   |
E | K | X | V | A | I | X | K | T | K | P | G | Y | G | A | E | L | V | E | V | D | V | P | K | P | G | P | G | E | V | L | I | K | V | L | A | T | S | I | C | G | T | D | L | H | I | Y | E | W | N | E | W | A | Q | S | R | I | K | P | P | Q | I | X | G | H | E | V | A | G | E | V | V | E | I | G | P | G | V | E | G |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |
| S | S | S | S | S |
|  |  |  |  |  |  |
|
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |
|
| S | S |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
| T | T |
|
| S |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | N | G | Q | Q | V | A | V | I | P | Y | V | A | C | Q | Q | C | P | A | C | K | S | G | R | T | N | C | C | E | K | I | S | V | I | G | V | H | Q | D | G | G | F | S | E | Y | L | S | V | P | V | A | N | I | L | P | A | D | G | I | D | P | Q | A | A | A | L | I | E | P | F | A | I | S | A | H | A | V | R | R |
Query Conservation |   |
  |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | E | V | G | D | Y | V | S | V | E | T | H | I | V | C | G | K | C | Y | A | C | R | R | G | Q | Y | H | V | C | Q | N | T | K | I | F | G | V | D | T | D | G | V | F | A | E | Y | A | V | V | P | A | Q | N | I | W | K | N | P | K | S | I | P | P | E | Y | A | T | L | Q | E | P | L | G | N | A | V | D | T | V | L |
Template Known Secondary structure |   |
|
| T | T |
|  |  |  |  |
|
|  |  |
|
| S |
| S |  |  |  |  | T | T |
| G | G | G |
| T | T |
|  |  | T | T | T | T | S |
|
| S | S | B | S |  |  |  |  |  | G | G | G |  |  |  |
|
| T | T | S |
|  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
  |
  |   |
158 | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | |
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | I | A | P | G | E | Q | V | L | V | V | G | A | G | P | I | G | L | G | A | A | A | I | A | K | A | D | G | A | Q | . |
V | V | V | A | D | T | S | P | A | R | R | E | H | V | A | T | R | L | E | L | P | L | L | D | P | S | A | E | D | F | D | A | Q | L | R | A | Q | F | G | G | S | L | A | Q | K | V | I | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
A | G | P | I | S | G | K | S | V | L | I | T | G | A | G | P | L | G | L | L | G | I | A | V | A | K | A | S | G | A | Y | P | V | I | V | S | E | P | S | D | F | R | R | E | L | A | K | K | V | G | A | D | Y | V | I | N | P | F | E | E | D | V | V | K | E | V | X | D | I | T | D | G | N | G | V | D | V | F | L | E |
Template Known Secondary structure |   |
T | S |
|
| T | T |
|
|  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |
| T | T | T | S |
|  |  |  |  |  |  |  |  | T | T | T | S |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
163 | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . |
  |
  |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | |
. | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | |
. | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | T | G | N | Q | H | A | M | N | N | T | V | N | L | I | R | H | G | G | T | V | V | F | V | G | L | F | K | G | E | L | Q | . |
F | S | D | P | E | F | H | K | K | E | T | T | M | M | G | S | R | N | A | T | . |
P | E | D | F | A | K | V | G | R | L | M | A | E | G | K | I | T | A | D | M | M | L | T | H | R | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
F | S | G | A | P | K | A | L | E | Q | G | L | Q | A | V | T | P | A | G | R | V | S | L | L | G | L | Y | P | G | K | V | T | I | D | F | N | N | L | I | I | F | K | A | L | T | I | Y | G | I | T | G | R | H | L | W | E | T | W | Y | T | V | S | R | L | L | Q | S | G | K | L | N | L | D | P | I | I | T | H | K | Y |
Template Known Secondary structure |   |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| S | S |
|
|
|
|
|  |  |  |  | T | T | T | T | T |
|  |  |  |  |
|
| S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
| G | G | G |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
243 | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
  |
  |   |
315 | |
. | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 |
Predicted Secondary structure |   |
 | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
Query SS confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | . |
F | A | T | L | A | E | T | Y | E | R | D | V | I | N | N | R | E | L | I | K | G | V | I | T | F |
Query Conservation |   |
  | . |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |   |
|   |   | . |   |   |   |   |   |   |   | . |
|
|
|
|
|   |
|
Template Sequence |   |
K | G | F | D | K | Y | E | E | A | F | E | . |
L | X | R | A | G | K | T | . |
G | K | V | V | F | X | L |
Template Known Secondary structure |   |
 | S | S | T | T |  |  |  |  |  |  | . |  |  |  | T | T |
|
| . | S |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  | . |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
323 | . | . | . | . | . | . | 330 | . | . | . | |
. | . | . | . | . | . | 340 | |
. | . | . | . | . | . | . |
  |