|   |
23 | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | G | K | E | V | A | I | E | C | Q | R | L | G | V | E | V | I | A | V | D | R | Y | A | D | A | P | A | M | H | V | A | H | R | S | H | V | I | N | M | L | D | G | D | A | L | R | R | V | V | E | L | E | K | P | H | Y | I | V | P | E | I | E | A | I | A | T | D | M | L | I | Q | L | E | E | E | G | L | N | V | V |
Query Conservation |   |
  |
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
|
|
|   |
|   |   |   |
|   |   |
|
|
|   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
Template Sequence |   |
S | T | Q | L | L | L | F | D | V | I | Q | K | G | V | N | F | E | V | L | D | E | Q | D | Q | F | L | K | L | W | H | N | S | H | I | E | Y | V | K | N | G | N | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | S | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  | S |
| S | S | S |
|  |  |  |  |  |  | T | T |  |  |  |  |  |  | T | T | T | B | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
429 | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
  |
  |   |
103 | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | |
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | |
|
|
. | . | 170 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  | . | . | . |  |
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | C | A | R | A | T | K | L | T | M | N | R | E | G | I | R | R | L | A | A | E | E | L | Q | L | P | T | S | T | Y | R | F | A | D | S | E | S | L | F | R | E | A | V | A | D | I | . |
G | Y | P | C | I | V | K | P | V | M | S | S | S | G | K | G | Q | T | F | . |
. |
. |
I | R | S | A | E | Q | L | A | Q | A | W |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . |
|   |
|   |
|
|
|
|   |   |   |   |
|
|   |
|
|   |   | . | . | . |
|   |   |   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |   |   |
|
|   |
|
|   |   |
|
|   | . |
|
|   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|   |   |
|   |
|
|
|
|
|
|   |   |
|   |   |
|   |
|
|   |
|
|   |   |
|   |   |   |
|
|
|   |   |
|   |
Template Sequence |   |
D | N | Y | I | V | P | L | A | M | A | N | K | V | V | T | K | K | . |
I | L | D | E | K | H | F | P | T | P | F | G | D | E | F | T | D | R | K | E | A | L | N | Y | F | S | Q | I | Q | D | K | P | I | V | V | K | P | K | S | T | N | F | G | L | G | I | S | I | F | K | T | S | A | N | L | A | S | Y | E | K | A | I |
Template Known Secondary structure |   |
S |
| T |  |  |  |  |  | T | T | T | S |  |  |  |  |  | . |  |  |  |  | T | T |
|
|
|
|
|
|
|
|  |  | T | T | T | T |  |  |  |  |  |  |  | S | S | S | S |
|  |  |  |  |  | T | T |
|
| S | S | S | S |
|  |  |  | S | S |
|
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  | . |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
474 | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | |
. | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . |
  |
  |   |
179 | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
K | Y | A | Q | Q | G | G | R | A | G | A | G | R | V | I | V | E | G | V | V | K | F | D | F | E | I | T | L | L | T | V | S | A | V | D | G | V | H | F | C | A | P | V | G | H | R | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|   |   |   |   |   | . | . | . | . |   |
|
|
|
|
|
|
|   |
| . |   |
|   |
|
|   |
|
| . | . | . |
|
|   |
|
|
|
|   |   |
|   |
|   |   |
|
|
|
|
|   |   |
|
|   |
|
|
|   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |
Template Sequence |   |
D | I | A | F | T | E | D | S | . |
. |
. |
. |
A | I | L | V | E | E | Y | I | E | G | . |
T | E | Y | R | F | F | V | L | . |
. |
. |
E | G | D | C | I | A | V | L | L | R | V | A | A | N | V | V | G | D | G | I | H | T | I | S | Q | L | V | K | L | K | N | Q | N | P | L | R | G | Y | D | H | R | S | P | L | E | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| S | . | . | . | . |  |  |  |  |  |  |
|
|
| S | . |  |  |  |  |  |  |  |  | . | . | . | T | T |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |  | T | T |
| T | T |  |  | S | S | S |
|
| S |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
| . | . | . | . |
|  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |  | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
553 | . | . | . | . | . | . | 560 | |
|
|
|
. | . | . | . | . | . | . | . | . | 570 | |
. | . | . | . | . | . | . | . | |
|
|
. | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
226 | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | D | G | D | Y | R | E | S | W | Q | P | Q | Q | M | S | P | L | A | L | E | R | A | Q | E | I | A | R | K | V | V | L | A | L | G | G | Y | G | L | F | G | V | E | L | F | V | C | . |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|   |   |
|   |   |   |
|
|
|   |   |   | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |
|   |   |
|
|   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |
|
|
|
|   |   |   |
|
|
|   |   |
|   |
|   |   |   |   |
|
|   |
|
|
|   |
|
|
|
| . |   |
|
|
|
|
|
|
|
|
|
|
|   |
Template Sequence |   |
I | E | L | G | E | V | E | Q | L | M | L | E | Q | Q | G | Y | T | V | N | S | I | P | P | E | G | T | K | I | E | L | R | R | N | S | N | I | S | T | G | G | D | S | I | D | V | T | N | T | M | D | P | T | Y | K | Q | L | A | A | E | M | A | E | A | M | G | A | . |
W | V | C | G | V | D | L | I | I | P | N | A | T |
Template Known Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  | T | T |
|
| S | S |
|
|
|
| T | T |
|  |  |  | S |
| S | S |
|
| T | T | T | T |
|  |  |  |  |
| T | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| . | S | S |
|  |  |  |  |  |  | S |
| S | S |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
625 | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | |
. | . | . | . | . | . | . | . | . | 700 | . | . | . |
  |
  |   |
|
|
|
|
|
|
272 | . | . | . | . | . | . | . | 280 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
G | D | E | V | I | F | S | E | V | S | P | R | P | H |
Query Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |
|
|
|
|
|
|
|   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|
|
Template Sequence |   |
Q | A | Y | S | K | D | K | K | N | A | T | C | I | E | L | N | F | N | P | L |
Template Known Secondary structure |   |
S |
|
|
| T | T | T | T |
|
|  |  |  |  |  |  | S | S |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
704 | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . |
  |