|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
|
|
. |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
Query Sequence |   |
M | S | S | K | L | V | L | V | L | N | C | G | S | S | S | L | K | F | A | I | I | D | A | V | N | G | E | E | Y | L | S | G | L | A | E | C | F | H | L | P | E | A | R | I | K | W | K | M | D | G | N | K | Q | E | A | A | L | G | A | G | A | A | H | S | E | A | L | N | F | I | V | N | T | I | L | A | . |
. |
. |
Q |
Query Conservation |   |
|   |   |   |   |
|
|
|
|
|   |
|
|
|
|   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   | . | . | . |   |
Alig confidence |   |
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
Template Conservation |   |
|   | . | . | . |
|
|
|
|
|
|
|
|
|   |   |   |   |   |
|   |
| . |   |   |
|   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
L | S | . |
. |
. |
A | L | A | V | D | L | G | G | T | N | L | R | V | A | I | V | S | . |
M | K | G | E | I | V | K | K | Y | T | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | N | P | K | T | Y | E | E | R | I | N | L | I | L | Q | M | C | V | E | A | A | A | E |
Template Known Secondary structure |   |
|  | . | . | . |  |  |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  | . | T | T |
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
| . |
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
407 | . | |
|
|
. | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | |
. | . | . | . | 430 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | P | E | L | S | A | Q | L | T | A | I | G | H | R | I | V | H | G | G | E | K | Y | T | S | S | V | V | I | D | E | S | V | I | Q | G | I | K | D | A | A | S | F | A | P | L | H | N | P | A | H | L | I | G | I | E | E | A | L | K | S | F | P | Q | L | K | D | K | N | V | A | V | F | D | T | A | F | H | Q | T | M |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|
|
|
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
A | V | K | L | N | C | R | I | L | G | V | G | I | S | T | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  | T | T |
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
158 | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | E | E | S | Y | L | Y | A | L | P | Y | N | L | Y | K | E | H | G | I | R | R | Y | G | A | H | G | T | S | H | F | Y | V | T | Q | E | A | A | K | M | L | N | K | P | V | E | E | L | N | I | I | T | C | H | L | G | N | G | G | S | V | S | A | I | R | N | G | K | C | V | D | T | S | M | G | L | T | P | L | E | G |
Query Conservation |   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |
|
|   |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|   |
|
|   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . |
|   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |
|
|   |   | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
L | R | T | P | L | S | D | T | L | H | L | P | V | W | V | D | N | D | G | N | C | A | A | L | A | E | R | K | . |
. |
. |
F | G | Q | G | K | G | L | E | N | F | V | T | L | I | T | G | T | G | I | G | G | G | I | I | H | Q | H | E | L | I | H | G | S | S | F | C | A | A | E | L | G |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |
| S |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | T | S | T | T | T | T |
| S | S |  |  |  |  |  |  | S | S | S |  |  |  |  |  |  |  | T | T |  |  |
|
|
| T | T | S |
|
|
|
| G | G |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | |
|
|
. | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . |
  |
  |   |
238 | |
|
|
|
. | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | |
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . |
Predicted Secondary structure |   |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  | . |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | . |
. |
. |
. |
V | M | G | T | R | S | G | D | I | D | P | A | I | I | F | H | L | H | D | T | L | G | M | S | V | D | A | I | N | K | L | L | T | K | E | S | G | L | L | G | L | T | E | V | T | S | D | C | R | Y | V | E | D | N | . |
Y | A | T | K | E | D | A | K | R | A | M | D | V | Y | C | H | R | L | A | K |
Query Conservation |   |
| . | . | . | . |   |
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |
|
|
|
|
|   |
|
|   |
|   |
|   |
|   |
|   |   |   | . |   |   |
|
|   |   |
|   |
|
|   |
|   |
|   |
|
|
|   |
|
Alig confidence |   |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
| . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
Template Sequence |   |
H | L | V | V | S | L | D | G | P | D | C | S | C | G | S | H | G | C | I | E | A | Y | A | S | G | M | A | L | . |
Q | R | E | A | K | K | L | H | D | E | D | L | L | L | V | E | G | M | S | . |
A | V | G | A | L | H | L | I | Q | A | A | K | L | G | N | A | K | A | Q | S | I | L | R | T | A | G | T | A | L | G | L |
Template Known Secondary structure |   |
G |
| B |
|
| S | S |
|
| B |
| T | T | S |
| B | S | B |  |  |  |  |  | S |  |  |  |  | . |  |  |  |  |  |  |  |  |  | T | T |
| S |
|
| S | S |
|
| . |
|
|
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
569 | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | |
. | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | |
. | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . |
  |
  |   |
313 | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | |
. | . | 340 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | I | G | A | Y | T | A | L | M | D | G | R | L | D | A | V | V | F | T | G | G | I | G | E | N | . |
A | A | M | V | R | E | L | S | L | G | K | L |
Query Conservation |   |
  |
|
|
|   |   |
|   |
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|   |   |
|
|   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |   |
|   |
| . | . |   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
G | V | V | N | I | L | H | T | M | N | P | . |
. |
S | L | V | I | L | S | G | V | L | A | S | H | Y | I | H | I | V | K | D | V | I | R | Q | Q | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
| . | . | S |  |  |  |  |  | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
652 | . | . | . | . | . | . | . | 660 | . | . | |
|
. | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . |
  |