|   |
69 | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | |
. | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | |
|
. | . | . | . | 140 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | I | L | V | I | V | P | D | I | C | D | P | F | F | S | E | I | I | R | G | I | E | V | T | A | A | N | H | . |
G | Y | L | V | L | I | G | D | C | A | H | Q | N | Q | Q | E | K | T | F | I | D | L | I | I | T | K | Q | I | D | G | M | L | L | L | G | S | R | L | P | . |
. |
F | D | A | S | I | E | E | Q | R | N |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | I | G | V | A | Q | C | S | . |
D | D | S | W | R | H | K | M | N | D | E | I | L | R | E | A | M | F | Y | N | G | V | S | V | E | I | R | S | A | G | D | D | N | S | K | Q | A | E | D | V | H | Y | F | M | D | E | G | V | D | L | L | I | I | S | A | N | E | A | A | P | M | T | P | I | V | E | E | A | Y | Q | K |
Template Known Secondary structure |   |
 |  |  |  |  |  | S |
| . |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S |
|  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
34 | . | . | . | . | . | 40 | . | |
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . |
  |
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | |
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | |
|
. | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | P | P | M | V | M | A | N | E | F | A | P | E | L | E | L | P | . |
T | V | H | I | D | N | L | T | A | A | F | D | A | V | N | Y | L | Y | E | Q | . |
. |
G | H | K | R | I | G | C | I | A | G | P | E | E | M | P | L | C | H | Y | R | L | Q | G | Y | V | Q | A | L | R | R | C | G | I | M | V | D | P | Q | Y | I |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   | . | . |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   | . |   |   |   |   |   |   |   |
Template Sequence |   |
G | I | P | V | I | L | V | D | R | K | I | L | S | D | K | Y | T | A | Y | I | G | A | D | N | Y | E | I | G | R | S | V | G | N | Y | I | A | S | S | L | K | G | K | G | N | I | V | E | L | T | G | L | S | G | S | T | P | A | M | E | R | H | Q | G | F | M | A | A | I | S | K | F | P | . |
D | I | K | L | I | D | K |
Template Known Secondary structure |   |
T |
|
|  |  |  |  | S | S |
|
| S | S | S |
| S | S |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  | S |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | . |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
113 | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | |
. | . | . | . | . | 190 | . |
  |
  |   |
223 | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
|
|
|
. | . | . | . | 290 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  | . | . | . | . |  |  |  |
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | R | G | D | F | T | F | E | A | G | S | K | A | M | Q | Q | L | L | D | L | P | Q | P | P | T | A | V | F | C | H | S | D | V | M | A | L | G | A | L | S | Q | A | K | R | Q | G | L | K | V | P | E | D | L | S | I | I | G | F | D | N | I | D | L | . |
. |
. |
. |
T | Q | F | C | D | P | P | L | T | T | I | A | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |
|
|   |
|
|
|   |
|   |   |   |   | . | . | . | . |   |   |   |   |   |
|   |
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |   |
|   |
|
|   |   |
|
|   |   |   |
|   | . | . |   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |
Template Sequence |   |
A | D | A | A | W | E | R | G | P | A | E | I | E | M | D | S | M | L | R | R | H | P | K | I | D | A | V | Y | A | H | N | D | R | I | A | P | G | A | Y | Q | A | A | K | M | A | G | R | . |
. |
E | K | E | M | I | F | V | G | I | D | A | L | P | G | K | G | N | G | L | E | L | V | L | D | S | V | L | D | A | T | F |
Template Known Secondary structure |   |
 |  |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S |
|
|
|  |  |  |  | S | S | T | T |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . | T | T | S | S |  |  |  |  |  |  |
|
|
| S | T | T | S |  |  |  |  |  |  | T | T | S |
| S |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
192 | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | |
|
. | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . |
  |
  |   |
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | R | Y | E | I | G | R | E | A | M | L | L | L | L | D | Q | M | Q | G | Q | H | V | G | S | G | S | R | L | M | D | C | E | L | I | I | R | G | S | T | R |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   | . |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
Template Sequence |   |
I | Y | P | T | N | G | D | K | V | L | Q | L | A | M | D | I | L | E | K | K | P | Y | P | K | E | . |
T | V | M | N | T | A | V | V | D | R | T | N | A | H |
Template Known Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| S |  | . |  |  |  |
|
|
|  |  |  | T | T | T |  |  |
Template Predicted Secondary structure |   |
 |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  | . |  |  |
|
|  |  |  |  |
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | |
. | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
  |