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Job DescriptionP31456
Confidence99.18%DateThu Jan 5 11:47:48 GMT 2012
Rank145Aligned Residues294
% Identity14%Templatec2hkoA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:lysine-specific histone demethylase 1; PDBTitle: crystal structure of lsd1
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.... .....30.........40.....
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Query Sequence  EHFDVAIIGLGPAGSALARKLAG. KMQVIALDKKHQCGTEGFSKP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKI
Template Known Secondary structure 
S


BTT

SSSSSBSS

TTSS



SBT
TT


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   277..280.........290.........300.........310.........320.........330.........340.........350......
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation            
  
                                                                  
Template Sequence  KQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVK
Template Known Secondary structure 
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TTS
B

STTT


BSSSSB
B
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   357..360.........370.........380.........390.........400.........410.........420.........430......
 
   46...50...
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CGGLLAPD
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Template Conservation                                                                                  
Template Sequence  TQEELKELLNKMVNLKEKIKELHQQYKEAITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSR
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TTTTS


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   437..440.........450.........460.........470.........480.........490.........500.........510......
 
   54.....60.........70.........80.........90.........100.........110.........120.........130...
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Query Sequence  AQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPASVEVYHDSLCRKIWREDDKW
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Template Sequence  DRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTV. . . . RNGYSCVPVALAEGLDIKLNTAVRQVQYTASGC
Template Known Secondary structure  TS
GGGBBTTTTTGGGGG

BS

....TT
TTTTT

TTTT
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   525....530.........540.........550.........560....... ..570.........580.........590.........600
 
   134.... .140.........150.........160... ......170.........180.........190.
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Query Sequence  HVIFR. . . ADGWEQHITARYLVGADGANSMVRR. . . . . . . . . . . . . . . . . . . HLYPDHQIRKYVAIQQWFAEKHPVPFYS
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Template Conservation                    
 

 
 
   
          
 

     

         

 
 
    
         
Template Sequence  EVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGH
Template Known Secondary structure  TTS


TTTTT
SS
SSS


S



SS

S
TT
S

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   601........610.........620.........630.........640.........650.........660.........670.........680
 
   192.......200.........210.........220..... ....230.........240.........250.........260.....
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Query Sequence  CIFDNSITNCYSWSISKDGYFIFGGAYPMKDGQT. . . . . RFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGK.
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Template Conservation                        
     
  
      
  

    
  
                
  
  

   

Template Sequence  VGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGS
Template Known Secondary structure 

SSSSSTT
TTTTT
TTTTS
TTTS



S

TTT
TTTSSS
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   681........690.........700.........710.........720.........730.........740.........750.........760
 
   266...270.........280.........290.........300..
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . DNAFLIGEAAGFISASSLEGISYALDSTDILRSVLLK
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Template Sequence  YSYVAAGSSGNDYDLMAQPITPGPSQPIPRLFFAGEHTIRNYP. . . ATVHGALLSGLREAGRIAD
Template Known Secondary structure 

BTT

TS
B










STTT
SSST...TS
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   761........770.........780.........790.........800... ......810.........820..
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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