|   |
25 | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | |
|
|
. | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | L | K | L | G | F | L | V | K | Q | P | E | E | P | W | F | Q | T | E | W | K | F | A | D | K | A | G | K | D | L | G | F | E | V | I | K | I | A | V | . |
. |
. |
P | D | G | E | K | T | L | N | A | I | D | S | L | A | A | S | G | A | K | G | F | V | I | C | T | P | D | P | K | L | G | S | A | I | V | A | K | A |
Query Conservation |   |
  |   |   |
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   | . | . | . |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | E | K | I | C | A | I | Y | P | H | L | K | D | S | Y | W | L | S | V | N | Y | G | M | V | S | E | A | E | K | Q | G | V | N | L | R | V | L | E | A | G | G | Y | P | N | K | S | R | Q | E | Q | Q | L | A | L | C | T | Q | W | G | A | N | A | I | I | L | G | T | V | D | P | H | A | Y | E | H | N | L | K | S | W |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  | S |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
| S | S | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
|
| S | S | T | T | T | T | T | T | T | T |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . |
  |
  |   |
102 | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | G | Y | D | M | K | V | I | A | V | D | D | Q | F | V | N | A | K | G | K | P | M | D | T | V | P | L | V | M | M | A | A | T | K | I | G | E | R | Q | G | Q | E | L | Y | K | E | M | Q | K | R | G | W | D | V | K | E | S | A | V | M | A | I | T | A | N | E | L | D | T | A | R | R | R | T | T | G | S | M | D | A |
Query Conservation |   |
  |   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
Template Sequence |   |
V | G | N | T | P | V | F | A | T | V | N | Q | . |
L | D | L | D | E | E | Q | S | T | L | L | K | G | E | V | G | V | D | W | Y | W | M | G | Y | E | A | G | K | Y | L | A | E | R | H | P | K | G | S | G | . |
. |
. |
. |
. |
. |
K | T | N | I | A | L | L | L | G | P | R | T | K | P | V | T | T | G | F | Y | E | A |
Template Known Secondary structure |   |
 | T | T |
|
|  |  |  |
| S | S |
| . |
|
|
|
| T | T | T | T | T | S |  |  |  |  |  |
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| T | T | S |
| . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
110 | . | . | . | . | . | . | . | . | . | 120 | . | |
. | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . |
  |
  |   |
182 | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | A | A | G | F | P | E | K | Q | I | Y | Q | V | P | T | K | S | N | D | I | P | G | A | F | D | A | A | N | S | M | L | V | Q | H | P | E | V | K | H | W | L | I | V | G | M | N | D | S | T | V | L | G | G | V | R | A | T | E | G | Q | G | F | K | A | A | D | I | I | G | I | G | I | N | G | V | D | A | V | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   | . | . | . | . |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|   | . |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   | . |
Template Sequence |   |
I | K | N | S | D | . |
. |
. |
I | H | I | V | D | S | F | W | A | D | N | D | K | E | L | Q | R | N | L | V | Q | R | V | I | D | M | G | N | I | D | . |
. |
. |
. |
Y | I | V | G | S | A | V | A | I | E | A | A | I | S | E | L | R | S | A | D | K | . |
T | H | D | I | G | L | V | S | V | Y | L | S | H | G | V | . |
Template Known Secondary structure |   |
 | S | S | S | S | . | . | . |  |  |  |  |  |  |  |  |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
| S | . | . | . | . |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| . | T | T | T | S |  |  |  |  | S | S |
|
| T | T |  | . |
Template Predicted Secondary structure |   |
 |  |
|
|
| . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . | . | . |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
187 | . | . | 190 | . | |
|
|
. | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
|
|
|
. | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | |
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | |
  |
  |   |
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | L | S | K | A | Q | A | T | G | F | Y | G | S | L | L | P | S | P | D | V | H | G | Y | K | S | S | E | M | L | Y | N | W | V | A | K | D | V | E | P | P | K | F | T | E | V | T | D | V | V | L | I | T | R | D | N | F | K | E | E | L | E | K | K | G | L | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |
|   |   |
|   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
Y | R | G | L | L | R | N | K | V | L | F | A | P | T | D | K | M | V | Q | Q | G | R | L | S | V | M | Q | A | A | H | Y | L | R | H | Q | P | Y | E | K | Q | . |
. |
A | S | P | I | I | K | P | L | T | P | K | T | L | H | D | D | T | I | E | E | S | L | S |
Template Known Secondary structure |   |
. |  |  |  |  |  | T | T | S |
|
| B |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| T |  | . | . |  |
|
|
|
|  |  |  |
| G | G | G |
|
|  |  |  |  |  | T | T | S |
|
Template Predicted Secondary structure |   |
. |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . |  |  |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
258 | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | |
|
. | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
  |