|   |
26 | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
. | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | K | L | G | F | L | V | K | Q | P | E | E | P | W | F | Q | T | E | W | K | F | A | D | K | A | G | K | D | L | G | F | E | V | . |
I | K | I | A | V | P | D | G | E | K | T | L | N | A | I | D | S | L | A | A | S | G | A | K | G | F | V | I | C | T | P | D | P | K | L | G | S | A | I | V | A | K | A | R | G | Y |
Query Conservation |   |
  |   |
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | T | V | L | V | L | I | P | S | L | A | N | T | V | F | L | E | T | L | T | G | I | E | T | V | L | D | A | A | G | Y | Q | X | L | I | G | N | S | H | Y | D | A | G | Q | E | L | Q | L | L | R | A | Y | L | Q | H | R | P | D | G | V | L | I | T | G | L | S | H | A | . |
. |
E | P | F | E | R | I | L | S | Q | H |
Template Known Secondary structure |   |
|  |  |  |  |  |  | S |
| S | T | T |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  | S | S |
|
|
| . | . | T | T |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
. | 140 | . | . | . | . | . | . | . | . |
  |
  |   |
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | M | K | V | I | A | V | D | D | Q | F | V | N | A | K | G | K | P | M | D | T | V | P | L | V | M | M | A | A | T | K | I | G | E | R | Q | G | Q | E | L | Y | K | E | M | Q | K | R | G | W | D | V | K | E | S | A | V | M | A | I | T | A | N | E | L | D | T | A | R | R | R | T | T | G | S | M | D | A | L | K | A |
Query Conservation |   |
  |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |
Template Sequence |   |
A | L | P | V | V | Y | X | X | D | . |
. |
. |
. |
. |
. |
. |
L | A | D | D | G | R | C | C | V | G | F | S | Q | E | D | A | G | A | A | I | T | R | H | L | L | S | R | G | K | R | R | . |
. |
. |
. |
. |
. |
. |
. |
I | G | F | L | G | A | Q | L | D | E | R | V | X | K | R | L | D | G | Y | R | A | A | L | D | A |
Template Known Secondary structure |   |
T |
|
|  |  |  |  |  | S | . | . | . | . | . | . | . |
|
| S | S | S |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S | . | . | . | . | . | . | . | . |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
149 | 150 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . |
  |
  |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | |
. | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | F | P | E | K | Q | I | Y | Q | V | P | T | K | S | N | D | I | P | G | A | F | D | A | A | N | S | M | L | V | Q | H | P | E | V | K | H | W | L | I | V | G | M | N | D | S | T | V | L | G | G | V | R | A | T | E | G | Q | G | F | K | A | A | . |
D | I | I | G | I | G | I | N | G | V | D | A | V | S | E | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |
|   |   |   |   | . |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
A | D | C | R | D | A | G | L | E | W | L | D | P | Q | P | S | S | X | Q | X | G | A | D | X | L | D | R | A | L | A | E | R | P | D | C | D | . |
. |
A | L | F | C | C | N | D | D | L | A | I | G | A | L | A | R | S | Q | Q | L | G | I | A | V | P | E | R | L | A | I | A | G | F | N | D | L | Q | P | A | A | W | C |
Template Known Secondary structure |   |
 | T |
|
|
| G | G | G |  |  |  |  |
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
| . | . |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | T | T |
|  |  |  |
| S | B |
|
|  |  |  |  | T | S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
214 | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . |
  |
  |   |
264 | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | K | A | Q | A | T | G | F | Y | G | S | L | L | P | S | P | D | V | H | G | Y | K | S | S | E | M | L | Y | N | W | V | A | K | D | V | E | P | P | K | F | T | E | V | T | D | V | V | L | I | T | R | D | N | F | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . |   |   |   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
| . |   |   |   |
|   |   |
|   |
|
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
T | P | P | L | T | T | V | A | T | P | R | R | D | I | G | V | H | A | A | K | A | L | L | Q | L | I | D | G | E | E | P | A | S | R | R | A | D | L | . |
G | F | R | L | X | L | R | R | S | S | E |
Template Known Secondary structure |   |
. | . | . | . | . | S | S |
|
| B |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S |
| S |  |  |  |
| . |
|
|  |  |  |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
292 | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | |
330 | . | . | . | . | . | . | . | . | . | 340 |
  |