|   |
24 | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
. | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | N | L | K | L | G | F | L | V | K | Q | P | E | E | P | W | F | Q | T | E | W | K | F | A | D | K | A | G | K | D | L | G | F | E | V | . |
I | K | I | A | V | P | D | G | E | K | T | L | N | A | I | D | S | L | A | A | S | G | A | K | G | F | V | I | C | T | P | D | P | K | L | G | S | A | I | V | A | K | A | R |
Query Conservation |   |
  |   |   |   |
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|
|
|
|   |   |   | . |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |
Template Sequence |   |
R | S | N | I | I | A | F | I | V | P | D | . |
Q | N | P | F | F | T | E | V | L | T | E | I | S | H | E | C | Q | K | H | H | L | H | V | A | V | A | S | S | E | E | N | E | D | K | Q | Q | D | L | I | E | T | F | V | S | Q | N | V | S | A | I | I | L | V | P | V | K | S | K | F | . |
. |
. |
. |
Q | M | K | R | E |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  | S | S | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | T |
|  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |
|
| S | S | S | S |
| . | . | . | . |
|
|
| G | G |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
63 | . | . | . | . | . | . | 70 | . | . | . | |
. | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | |
|
|
|
. | . | . | . | . |
  |
  |   |
103 | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Y | D | M | K | V | I | A | V | D | D | Q | F | V | N | A | K | G | K | P | M | D | T | V | P | L | V | M | M | A | A | T | K | I | G | E | R | Q | G | Q | E | L | Y | K | E | M | Q | K | R | G | W | D | V | K | E | S | A | V | M | A | I | T | A | N | E | L | D | T | A | R | R | R | T | T | G | S | M | D | A | L |
Query Conservation |   |
  |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
| . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
W | L | K | I | P | I | M | T | L | D | R | E | L | E | S | T | S | . |
. |
. |
. |
. |
. |
L | P | S | I | T | V | D | N | E | E | A | A | Y | I | A | T | K | R | V | L | E | S | T | C | K | E | V | . |
. |
. |
. |
. |
. |
. |
G | L | L | L | A | N | P | N | I | S | T | T | I | G | R | K | N | G | Y | N | K | A | I |
Template Known Secondary structure |   |
G | T | T | S |
|  |  |  |  | S | S |
|
| T | T |
|
| . | . | . | . | . | . |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
| S |  | . | . | . | . | . | . | . |  |  |  |  |
|
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
138 | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . |
  |
  |   |
183 | . | . | . | . | . | |
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | |
. | . | 250 | . | . | . | . | . | . | . | . | . | 260 |
Predicted Secondary structure |   |
 |  |
|
|
|
| . |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . |
|  |  |  |  |  |  |
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | A | A | G | F | P | . |
E | K | Q | I | Y | Q | V | P | T | K | S | N | D | I | P | G | A | F | D | A | A | N | S | M | L | V | Q | H | P | E | V | K | H | W | L | I | V | G | M | N | D | S | T | V | L | G | G | V | R | A | T | E | G | Q | G | F | K | A | A | . |
D | I | I | G | I | G | I | N | G | V | D | A | V |
Query Conservation |   |
  |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |
|   |   |   |   | . |
|
|   |
|
|
|   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | E | F | D | L | N | V | N | P | S | L | I | H | Y | S | D | Q | Q | L | G | T | N | A | Q | I | Y | S | G | Y | E | A | T | K | T | L | L | S | K | G | I | K | G | I | V | A | T | N | H | L | L | L | L | G | A | L | Q | A | I | K | E | S | E | K | E | I | K | K | D | V | I | I | V | G | F | D | D | S | Y | W | N |
Template Known Secondary structure |   |
 |  | T | T |
|
|
|
| G | G | G |  |  |  |
|
| S | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
| B | T | T | T | B |  |  |  |  |  | S |
|
|  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
205 | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
  |
  |   |
261 | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | E | L | S | K | A | Q | A | T | G | F | Y | G | S | L | L | P | S | P | D | V | H | G | Y | K | S | S | E | M | L | Y | N | W | V | A | K | D | V | E | P | P | K | F | T | E | V | T | D | V | V | L | I | T | R | D | N | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |
Alig confidence |   |
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   | . | . | . | . | . |   |   |   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |
|   |   |   |   |   | . | . | . |   |   |
|   |   |   |
|
|   |
|   |
|
|
Template Sequence |   |
E | I | Y | . |
. |
. |
. |
. |
T | P | K | L | T | V | I | S | Q | P | V | K | E | M | G | Q | V | A | A | K | M | I | Y | K | L | I | K | G | K | D | V | T | S | . |
. |
. |
I | K | L | S | T | K | L | I | I | R | E | S | C |
Template Known Secondary structure |   |
 |  | S | . | . | . | . | . | S | S |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
| . | . | . |  |  |  |
|
|  |  |  |
|
| S | T | T |
Template Predicted Secondary structure |   |
 |  |
| . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
285 | . | . | |
|
|
|
|
. | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | |
|
|
. | . | . | . | . | . | . | . | . | 330 | . | . | . |
  |