Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.
Sequence		M	K	K	K	P	V	A	Q	L	E	R	Q	H	S	L	L	E	N	P	C	A	Y	G	L	L	S	Q	F	Q	A	A	I	V	V	N	C	F	T	L	N	K	I	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2a93 chain B Region: 6 - 17 Aligned: 12 Modelled: 12 Confidence: 10.6% Identity: 50% PDB header:leucine zippers Chain: B: PDB Molecule:c-myc-max heterodimeric leucine zipper; PDBTitle: nmr solution structure of the c-myc-max heterodimeric2 leucine zipper, 40 structures Phyre2 PDB 1dip chain A Region: 6 - 32 Aligned: 27 Modelled: 27 Confidence: 6.4% Identity: 33% PDB header:acetylation Chain: A: PDB Molecule:delta-sleep-inducing peptide immunoreactive PDBTitle: the solution structure of porcine delta-sleep-inducing2 peptide immunoreactive peptide, nmr, 10 structures Phyre2 PDB 1u2u chain A Region: 4 - 21 Aligned: 18 Modelled: 18 Confidence: 6.2% Identity: 50% PDB header:transcription Chain: A: PDB Molecule:general control protein gcn4; PDBTitle: nmr solution structure of a designed heterodimeric leucine2 zipper Phyre2 PDB 3he5 chain A Region: 6 - 18 Aligned: 13 Modelled: 13 Confidence: 5.8% Identity: 62% PDB header:de novo protein Chain: A: PDB Molecule:synzip1; PDBTitle: heterospecific coiled-coil pair synzip2:synzip1 Phyre2 1 c2a93B_ 2 c1dipA_ 3 c1u2uA_ 4 c3he5A_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2a93B_ 10.6 50 PDB header:leucine zippers Chain: B: PDB Molecule:c-myc-max heterodimeric leucine zipper; PDBTitle: nmr solution structure of the c-myc-max heterodimeric2 leucine zipper, 40 structures 2 c1dipA_ 6.4 33 PDB header:acetylation Chain: A: PDB Molecule:delta-sleep-inducing peptide immunoreactive PDBTitle: the solution structure of porcine delta-sleep-inducing2 peptide immunoreactive peptide, nmr, 10 structures 3 c1u2uA_ 6.2 50 PDB header:transcription Chain: A: PDB Molecule:general control protein gcn4; PDBTitle: nmr solution structure of a designed heterodimeric leucine2 zipper 4 c3he5A_ 5.8 62 PDB header:de novo protein Chain: A: PDB Molecule:synzip1; PDBTitle: heterospecific coiled-coil pair synzip2:synzip1

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0