Job Description Q46811 Confidence 99.42% Date Wed Jan 25 15:21:12 GMT 2012 Rank 145 Aligned Residues 291 % Identity 20% Template c2fptA_ PDB info PDB header:oxidoreductase Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors Resolution 2.40 Å

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		37	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.			.	100	.	.	.	.	.		.	.	.	.	110	.	.	.
Predicted Secondary structure																																																																.	.								.
Query SS confidence																																																																.	.								.
Query Sequence		S	P	V	K	G	K	T	V	S	V	F	G	E	T	C	A	T	P	V	G	P	A	A	G	P	H	T	Q	L	A	Q	N	I	V	T	S	W	L	T	G	G	R	F	I	E	L	K	T	V	Q	I	L	D	R	L	E	L	E	K	P	C	I	.	.	D	A	E	D	E	C	F	.	N	T	E	W	S	T	E	F
Query Conservation																																																																.	.								.
Alig confidence																																	.																															.	.								.
Template Conservation																																	.
Template Sequence		Q	D	S	D	M	L	E	V	R	V	L	G	H	K	F	R	N	P	V	G	I	A	A	G	F	D	K	H	G	E	A	.	V	D	G	L	Y	K	M	G	F	G	F	V	E	I	G	S	V	T	P	K	P	Q	E	G	N	P	R	P	R	V	F	R	L	P	E	D	Q	A	V	I	N	R	Y	G	F	N	S	H
Template Known Secondary structure					G	G	G					T	T				S	S	S					T	T	T	T	T	T	S	S		.							T	T		S									S	S		B			S		S							G	G	G	T										B
Template Predicted Secondary structure																																	.
Template SS confidence
		74	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.		.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.
		114	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	L	L	K	A	W	D	E	Y	L	K	A	W	F	A	L	H	L	L	E	A	M	F	Q	P	S	D	S	G	K	S	F	I	F	N	M	S	V	G	Y	N	L	E	G	I	K	Q	P	P	M	Q	Q	F	I	D	N	M	M	D	A	S	D	H	P	K	F	A	Q	Y	R	D	T	L	N	K	L	L	Q	D	D
Query Conservation
Alig confidence																						.	.	.	.	.	.	.	.																	.	.																					.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																						.	.	.	.	.	.	.	.																	.	.																					.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		G	L	S	V	V	E	H	R	L	R	A	R	Q	Q	K	Q	A	K	L	T	.	.	.	.	.	.	.	.	E	D	G	L	P	L	G	V	N	L	G	K	N	K	T	S	.	.	V	D	A	A	E	D	Y	A	E	G	V	R	V	L	G	P	L	A	D	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure												T	T									.	.	.	.	.	.	.	.		T	T											T	T		.	.	S														G	G	G		S		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																						.	.	.	.	.	.	.	.																	.	.																					.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		153	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.									.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.			.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.
		194	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.						.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.
Predicted Secondary structure																																										.	.	.	.	.
Query SS confidence																																										.	.	.	.	.
Query Sequence		A	F	L	A	R	H	G	L	Q	E	K	R	E	S	L	Q	A	L	P	A	R	I	P	T	S	M	V	H	G	V	T	L	S	T	M	H	G	C	P	P	.	.	.	.	.	H	E	I	E	A	I	C	R	Y	M	L	E	E	K	G	L	N	T	F	V	K	L	N	P	T	L	L	G	Y	A	R	V	R	E	I
Query Conservation																																										.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.			.	.	.	.	.	.	.	.	.	.	.	.																				.	.	.	.	.																									.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.			.	.	.	.	.	.	.	.	.	.	.	.																																																	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	L	V	.	.	.	.	.	.	.	.	.	.	.	.	V	N	V	S	S	P	N	T	A	G	L	R	S	L	Q	G	K	A	E	L	R	R	L	L	T	K	V	L	Q	E	R	D	G	L	R	R	V	H	R	P	A	V	L	V	K	I	A	P	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.			.	.	.	.	.	.	.	.	.	.	.	.						T	T	S	T	T	S	G	G	G	G	S																	T	S		G	G	G										S	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.			.	.	.	.	.	.	.	.	.	.	.	.																																																	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
									209	210													.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.
		269	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320			.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.
Predicted Secondary structure																																																						.	.
Query SS confidence																																																						.	.
Query Sequence		L	D	V	C	G	F	G	Y	I	G	L	K	E	E	S	F	D	H	D	L	K	L	T	Q	A	L	E	M	L	E	R	L	M	A	L	A	K	E	K	S	L	G	F	G	V	K	L	T	N	T	L	G	.	.	T	I	N	N	K	G	A	L	P	G	E	E	M	Y	M	S	G	R	A	L	F	P	L	S	I	N
Query Conservation																																																						.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.												.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	L	T	S	Q	D	K	E	D	I	A	S	V	V	K	E	L	G	.	.	.	.	.	I	D	G	L	I	V	T	N	T	T	V	S	R	P	A	G	L	Q	G	A	L	R	S	E	T	G	G	L	S	G	K	P	L	R	D	L	S	T	Q
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																		T	.	.	.	.	.										B	S				T	T				T	T	T	T	S	S	S
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																			.	.	.	.	.
Template SS confidence
																				259	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.						.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.
		347	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.		.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
Predicted Secondary structure																						.
Query SS confidence																						.
Query Sequence		V	A	A	V	L	S	R	A	F	D	G	K	L	P	I	S	Y	S	G	G	.	A	S	Q	L	T	I	R	D	I	F	D	T	G	I	R	P	I	T	M	A	T	D	L	L	K	P	G	G	Y	L	R	L	S	A	C	M	R	E	L	E
Query Conservation																						.
Alig confidence																						.																										.
Template Conservation																																																.
Template Sequence		T	I	R	E	M	Y	A	L	T	Q	G	R	V	P	I	I	G	V	G	G	V	S	S	G	Q	D	A	L	E	K	I	R	A	G	A	S	L	V	Q	L	Y	T	A	L	T	F	.	W	G	P	P	V	V	G	K	V	K	R	E	L	E
Template Known Secondary structure										T	T	T		S						S	S			S											T		S					S						.			T
Template Predicted Secondary structure																																																.
Template SS confidence
		316	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.		.	.	.	.	.	.	.	.	370	.	.	.	.	.

No model constructed - rank, confidence too low

---

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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