Job Description Q46811 Confidence 100.00% Date Wed Jan 25 15:21:12 GMT 2012 Rank 1 Aligned Residues 485 % Identity 26% Template c1gthD_ PDB info PDB header:oxidoreductase Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase; PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil Resolution 2.25 Å

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		367	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	S	Q	L	T	I	R	D	I	F	D	T	G	I	R	P	I	T	M	A	T	D	L	L	K	P	G	G	Y	L	R	L	S	A	C	M	R	E	L	E	G	S	D	A	W	G	L	D	H	V	D	V	E	R	L	N	R	L	A	A	D	A	L	T	M	E	Y	T	Q	K	H	W	K	P	E	E	R	I	E	V
Query Conservation
Alig confidence													.	.																																					.	.	.	.	.	.	.	.	.	.	.
Template Conservation													.	.																																					.	.	.	.	.	.	.	.	.	.	.
Template Sequence		K	D	V	A	D	I	E	S	I	L	A	.	.	L	N	P	R	T	Q	S	H	A	A	L	H	S	T	L	A	K	K	L	D	K	K	H	W	K	R	N	P	D	K	N	C	F	H	C	E	.	.	.	.	.	.	.	.	.	.	.	K	L	E	N	N	F	D	D	I	K	H	T	T	L	G	E	R	G	A	L
Template Known Secondary structure		S									T	T	.	.	T	S					S	S																			S			T	T						.	.	.	.	.	.	.	.	.	.	.			T	T							T	T
Template Predicted Secondary structure													.	.																																					.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		7	.	.	10	.	.	.	.	.	.	.			.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.												.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.
		447	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.			.	.	.	510	.	.	.	.	.	.	.	.		.	520	.	.	.
Predicted Secondary structure																																																														.	.													.
Query SS confidence																																																														.	.													.
Query Sequence		A	E	D	L	P	L	T	D	C	Y	V	A	P	C	V	T	A	C	A	I	K	Q	D	I	P	E	Y	I	R	L	L	G	E	H	R	Y	A	D	A	L	E	L	I	Y	Q	R	N	A	L	P	A	I	T	G	H	I	C	D	H	Q	.	.	C	Q	Y	N	C	T	R	L	D	Y	D	S	.	A	L	N	I	R
Query Conservation																																																														.	.													.
Alig confidence																																																														.	.													.
Template Conservation
Template Sequence		R	E	A	M	R	C	L	K	C	A	D	A	P	C	Q	K	S	C	P	T	H	L	D	I	K	S	F	I	T	S	I	S	N	K	N	Y	Y	G	A	A	K	M	I	F	S	D	N	P	L	G	L	T	C	G	M	V	C	P	T	S	D	L	C	V	G	G	C	N	L	Y	A	T	E	E	G	S	I	N	I	G
Template Known Secondary structure											T	T						T	S	T	T													T	T														T	T										G	G	G	S	G	G	G	G		G	G	G	G	S	T	T
Template Predicted Secondary structure
Template SS confidence
		74	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.
		524	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.								.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.		.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.
Predicted Secondary structure																										.	.	.	.	.	.	.																													.
Query SS confidence																										.	.	.	.	.	.	.																													.
Query Sequence		E	L	K	K	V	A	L	E	K	G	W	D	E	Y	K	Q	R	W	H	K	P	A	G	S	.	.	.	.	.	.	.	G	S	R	H	P	V	A	V	I	G	A	G	P	A	G	L	A	A	G	Y	F	L	A	R	A	G	H	P	.	V	T	L	F	E	R	E	A	N	A	G	G	V	V	K	N	I	I	P	Q
Query Conservation																										.	.	.	.	.	.	.																													.
Alig confidence																										.	.	.	.	.	.	.																													.
Template Conservation
Template Sequence		G	L	Q	Q	F	A	S	E	V	F	K	A	M	N	I	P	Q	I	R	N	P	C	L	P	S	Q	E	K	M	P	E	A	Y	S	A	K	I	A	L	L	G	A	G	P	A	S	I	S	C	A	S	F	L	A	R	L	G	Y	S	D	I	T	I	F	E	K	Q	E	Y	V	G	G	L	S	T	S	E	I	P	Q
Template Known Secondary structure															T				B			T	T	S			G	G	G	S		G	G	G	G									S														T									S	S	S	S		S	T					T	S		T
Template Predicted Secondary structure
Template SS confidence
		154	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
		596	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.				.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.				.	.	.	.	660	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																														.	.	.																																	.	.	.
Query SS confidence																														.	.	.																																	.	.	.
Query Sequence		F	R	I	P	A	E	L	I	Q	H	D	I	D	F	V	A	A	H	G	V	K	F	E	Y	G	C	S	P	.	.	.	D	L	T	I	E	Q	L	K	N	Q	G	F	H	Y	V	L	I	A	T	G	T	D	K	N	S	G	V	K	L	A	G	D	.	.	.	N	Q	N	V	W	K	S	L	P	F	L	R	E	Y
Query Conservation																														.	.	.																																	.	.	.
Alig confidence																														.	.	.																																	.	.	.
Template Conservation
Template Sequence		F	R	L	P	Y	D	V	V	N	F	E	I	E	L	M	K	D	L	G	V	K	I	I	C	G	K	S	L	S	E	N	E	I	T	L	N	T	L	K	E	E	G	Y	K	A	A	F	I	G	I	G	L	P	E	P	K	T	D	D	I	F	Q	G	L	T	Q	D	Q	G	F	Y	T	S	K	D	F	L	P	L	V
Template Known Secondary structure		T	T	S														T	T	T						S			B	S	T	T	S	B								T	T																	G	G	G	T	T			T	T	T	T
Template Predicted Secondary structure
Template SS confidence
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.
		670	.	.	.	.	.											.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.
Predicted Secondary structure								.	.	.	.	.	.	.	.	.	.
Query SS confidence								.	.	.	.	.	.	.	.	.	.
Query Sequence		N	K	G	T	A	L	.	.	.	.	.	.	.	.	.	.	K	L	G	K	H	V	V	V	V	G	A	G	N	T	A	M	D	C	A	R	A	A	L	R	V	P	G	V	E	K	A	T	I	V	Y	R	R	S	L	Q	E	M	P	A	W	R	E	E	Y	E	E	A	L	H	D	G	V	E	F	R	F	L	N	N
Query Conservation								.	.	.	.	.	.	.	.	.	.
Alig confidence								.	.	.	.	.	.	.	.	.	.																										.
Template Conservation																																											.
Template Sequence		A	K	S	S	K	A	G	M	C	A	C	H	S	P	L	P	S	I	R	G	A	V	I	V	L	G	A	G	D	T	A	F	D	C	A	T	S	A	L	R	C	.	G	A	R	R	V	F	L	V	F	R	K	G	F	V	N	I	R	A	V	P	E	E	V	E	L	A	K	E	E	K	C	E	F	L	P	F	L	S
Template Known Secondary structure							T	T	T		S	S									S								S													T	.	T		S							S	S		G	G	G			S											T	T						S
Template Predicted Secondary structure																																											.
Template SS confidence
		314	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.		.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.
		740	.	.	.	.	.		.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.			.	.	.	800	.	.	.	.	.	.	.	.	.	810		.	.	.	.	.
Predicted Secondary structure								.																																																				.	.															.
Query SS confidence								.																																																				.	.															.
Query Sequence		P	E	R	F	D	A	.	D	G	T	L	T	L	R	V	M	S	L	G	E	P	D	E	K	G	R	R	R	P	V	E	T	N	E	T	V	T	L	L	V	D	S	L	I	T	A	I	G	E	Q	Q	D	T	E	A	L	N	A	.	.	M	G	V	P	L	D	K	N	G	W	P	D	V	D	.	H	N	G	E	T
Query Conservation								.																																																				.	.															.
Alig confidence								.																								.																												.	.															.
Template Conservation																																.
Template Sequence		P	R	K	V	I	V	K	G	G	R	I	V	A	V	Q	F	V	R	T	E	Q	D	E	T	G	K	W	N	E	D	.	E	D	Q	I	V	H	L	K	A	D	V	V	I	S	A	F	G	S	V	L	R	D	P	K	V	K	E	A	L	S	P	I	K	F	N	R	W	D	L	P	E	V	D	P	E	T	M	Q	T
Template Known Secondary structure									S	S	S													S	S	S						.										S																		T	T	T	T	S		B		T	T	S	S	B				T	T	T		B
Template Predicted Secondary structure																																.
Template SS confidence
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.		.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.
		816	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	L	T	D	V	F	M	I	G	D	V	Q	R	G	P	S	S	I	V	A	A	V	G	T	A	R	R	A	T	D	A	I	L	S	R	E	N	I	R	S	H	Q	N	D	K	Y	W	N	N	V	N
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	E	P	W	V	F	A	G	G	D	I	V	G	M	A	N	T	T	V	E	S	V	N	D	G	K	Q	A	S	W	Y	I	H	K	Y	I	Q	A	Q	Y	G	A	S	V	S	A	K	P	E	L	P
Template Known Secondary structure		S	S	T	T					G	G	G	G	T				S																							T	T					S	S
Template Predicted Secondary structure
Template SS confidence
		472	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.