Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP23876
DateThu Jan 5 11:40:14 GMT 2012
Unique Job ID490a821918ebcda5

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1l7va_
Top template information
Fold:ABC transporter involved in vitamin B12 uptake, BtuC
Superfamily:ABC transporter involved in vitamin B12 uptake, BtuC
Family:ABC transporter involved in vitamin B12 uptake, BtuC
Confidence and coverage
Confidence:100.0% Coverage: 94%
313 residues ( 94% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAFSGTCQSADCTIVLDAR
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?
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   .........70.........80.........90.........100.........110.........120
Sequence  LPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQ
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??



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   .........130.........140.........150.........160.........170.........180
Sequence  LAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLTSGIALLNPDVYDQL
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   .........190.........200.........210.........220.........230.........240
Sequence  RFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLI
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   .........250.........260.........270.........280.........290.........300
Sequence  GLLAITVLCGSATAIVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIG
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   .........310.........320.........330....
Sequence  RVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
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???????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1l7v chain A

3D model

Region: 6 - 328
Aligned: 313
Modelled: 323
Confidence: 100.0%
Identity: 32%
Fold: ABC transporter involved in vitamin B12 uptake, BtuC
Superfamily: ABC transporter involved in vitamin B12 uptake, BtuC
Family: ABC transporter involved in vitamin B12 uptake, BtuC

Phyre2

PDB 2nq2 chain A

3D model

Region: 10 - 328
Aligned: 304
Modelled: 319
Confidence: 100.0%
Identity: 31%
PDB header:metal transport
Chain: A: PDB Molecule:hypothetical abc transporter permease protein
PDBTitle: an inward-facing conformation of a putative metal-chelate2 type abc transporter.

Phyre2

PDB 2b2h chain A

3D model

Region: 58 - 237
Aligned: 169
Modelled: 180
Confidence: 56.0%
Identity: 14%
PDB header:transport protein
Chain: A: PDB Molecule:ammonium transporter;
PDBTitle: ammonium transporter amt-1 from a. fulgidus (as)

Phyre2

PDB 3dh4 chain A

3D model

Region: 12 - 216
Aligned: 195
Modelled: 205
Confidence: 40.4%
Identity: 13%
PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus

Phyre2

PDB 3kp9 chain A

3D model

Region: 59 - 172
Aligned: 104
Modelled: 114
Confidence: 18.1%
Identity: 13%
PDB header:blood coagulation,oxidoreductase
Chain: A: PDB Molecule:vkorc1/thioredoxin domain protein;
PDBTitle: structure of a bacterial homolog of vitamin k epoxide reductase

Phyre2

PDB 3lrc chain C

3D model

Region: 138 - 332
Aligned: 187
Modelled: 195
Confidence: 11.2%
Identity: 11%
PDB header:transport protein
Chain: C: PDB Molecule:arginine/agmatine antiporter;
PDBTitle: structure of e. coli adic (p1)

Phyre2

PDB 1q1h chain A

3D model

Region: 223 - 244
Aligned: 22
Modelled: 22
Confidence: 9.6%
Identity: 18%
PDB header:transcription
Chain: A: PDB Molecule:transcription factor e;
PDBTitle: an extended winged helix domain in general transcription2 factor e/iie alpha

Phyre2
1

d1l7va_
2

c2nq2A_
3

c2b2hA_
4

c3dh4A_
5

c3kp9A_
6

c3lrcC_
7

c1q1hA_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1l7va_



100.0 32 Fold:ABC transporter involved in vitamin B12 uptake, BtuC
Superfamily:ABC transporter involved in vitamin B12 uptake, BtuC
Family:ABC transporter involved in vitamin B12 uptake, BtuC
2c2nq2A_



100.0 31 PDB header:metal transport
Chain: A: PDB Molecule:hypothetical abc transporter permease protein
PDBTitle: an inward-facing conformation of a putative metal-chelate2 type abc transporter.
3c2b2hA_



56.0 14 PDB header:transport protein
Chain: A: PDB Molecule:ammonium transporter;
PDBTitle: ammonium transporter amt-1 from a. fulgidus (as)
4c3dh4A_



40.4 13 PDB header:transport protein
Chain: A: PDB Molecule:sodium/glucose cotransporter;
PDBTitle: crystal structure of sodium/sugar symporter with bound galactose from2 vibrio parahaemolyticus
5c3kp9A_



18.1 13 PDB header:blood coagulation,oxidoreductase
Chain: A: PDB Molecule:vkorc1/thioredoxin domain protein;
PDBTitle: structure of a bacterial homolog of vitamin k epoxide reductase
6c3lrcC_



11.2 11 PDB header:transport protein
Chain: C: PDB Molecule:arginine/agmatine antiporter;
PDBTitle: structure of e. coli adic (p1)
7c1q1hA_



9.6 18 PDB header:transcription
Chain: A: PDB Molecule:transcription factor e;
PDBTitle: an extended winged helix domain in general transcription2 factor e/iie alpha

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0