|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | |
|
|
. | . | . | . | . | . | 50 | . | . | . | |
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
| . | . | . |
|  |  |  |  |  |
|
|
|
| . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | E | L | L | Q | Q | L | C | E | A | S | A | V | S | G | D | E | Q | E | V | R | D | I | L | I | N | T | L | E | P | C | V | N | E | I | T | F | D | G | L | G | . |
. |
. |
S | F | V | A | R | K | G | N | K | G | . |
. |
P | K | V | A | V | V | G | H | M | D | E | V | G | F | M | V | T | H | I | D | E | S | G | F |
Query Conservation |   |
|
|
|
|   |   |
|
|   |
|
|
|   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |
| . | . | . |
|
|
|
|   |   |   |   |   |   | . | . |   |   |
|   |
|   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
Template Conservation |   |
|   |   |   |   |   |
|   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |
|   |
|
| . | . | . | . | . | . | . | . | . |
|   |
Template Sequence |   |
I | E | I | S | H | R | I | H | E | R | P | E | L | G | N | E | E | I | F | A | S | R | T | L | I | D | R | L | K | E | H | D | F | E | I | E | T | E | I | A | G | H | A | T | G | F | I | A | T | Y | D | S | G | L | D | G | P | A | I | G | F | L | A | E | Y | D | A | L | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | S |
|
| B | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
| S | S | S | S |
|  |  |  |  |  |  |
|
|
| B |
| T | . | . | . | . | . | . | . | . | . | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
140 | . | . | . | . | . | . | . | . | . | 150 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | F | T | T | I | G | G | W | W | N | Q | S | M | L | N | H | R | V | T | I | R | T | H | K | G | V | K | I | P | G | V | I | G | S | V | A | P | H | A | L | T | E | K | Q | K | Q | Q | P | L | S | F | D | E | M | F | I | D | I | G | A | N | . |
. |
. |
. |
. |
. |
. |
S | R | E | E | V | E | K | R | G | V | E |
Query Conservation |   |
  |   |
|   |
|   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
| . | . | . |   |
|   |   |   | . | . |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | H | A | C | G | . |
. |
. |
H | N | I | I | G | . |
. |
T | A | S | V | L | G | A | I | G | L | K | Q | V | I | D | Q | I | G | G | K | V | V | V | L | G | C | P | A | E | E | G | G | E | N | G | S | A | K | A | S | Y | V | K | A | G | V | I | D | Q | I | D | I | A | L | X | I | H | P | G | N | E | T | Y | K | T |
Template Known Secondary structure |   |
S | S | S | S |
| . | . | . |  |  |  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |
|
|
| T | T |
|
| T | T |
|
|  |  |  |  |  |  |  |  | T | G | G | G | G |
| S |  |  |  |
|
|  |  |  | S | S | B | B |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
| . | . | . |
|
|  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
90 | . | . | . | . | |
|
|
. | . | . | . | . | |
|
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
  |
  |   |
151 | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | |
. | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | G | N | F | I | S | P | E | A | N | F | A | C | W | G | E | D | K | V | V | G | . |
K | A | L | D | N | R | I | G | C | A | M | M | A | E | L | L | Q | T | V | N | N | P | E | I | T | L | Y | G | V | G | S | V | E | E | E | V | G | L | R | G | A | Q | T | S | A | E | H | I | K | P | D | V | V | I | V | L | D | T |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |
|   |
| . | . |
|   |   |   |
|
|
|
|   |   |
|   |   |   |   |
|
Template Sequence |   |
I | D | T | L | A | V | D | V | L | D | V | K | F | Y | G | K | S | A | H | A | S | E | N | A | D | E | A | L | N | A | L | D | A | X | I | S | Y | F | N | G | V | A | Q | L | R | Q | H | I | . |
K | K | D | Q | R | V | H | G | V | I | L | D | G | . |
. |
G | K | A | A | N | I | I | P | D | Y | T | H | A | R | F | Y |
Template Known Secondary structure |   |
|
| B |
|  |  |  |  |  |  |  |  |  |  |
| B |
|
| B | T | T | T |
| G | G | G |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | . |
| T | T |
|  |  |  |  |  |  |  |  |
| . | . |
| S |
| T | T | B |
|
| S |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
. | . | . | . | . | . | . | 220 | . | . | . | . | . | |
|
. | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
  |
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
|
|
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | V | A | G | D | V | P | G | I | D | N | I | K | Y | P | L | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
L | G | Q | G | P | G | L | M | L | F | D | K | R | Y | F | P | . |
. |
. |
N | Q | K | L | V | A | A | L | K | S | C | A | A | H | N | D | L | P | L | Q | F | S | T | M | K | T | G | A | T | D | G | G | R | Y | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |
|   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   | . |
Template Sequence |   |
T | R | A | X | T | R | K | E | L | D | I | L | T | E | K | V | N | Q | I | A | R | G | A | A | I | Q | T | G | C | D | Y | E | F | G | P | I | Q | N | G | V | N | E | F | I | K | T | P | K | L | D | D | L | F | A | K | Y | A | E | E | V | G | E | A | V | I | D | D | D | F | G | Y | G | S | T | D | T | G | N | V | . |
Template Known Secondary structure |   |
 |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  | S | S |
|
| B |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| B |
|
| S |
|
|
|
| B |
|
| T |  |  |  |  | . |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | |
  |
  |   |
298 | . | 300 | . | . | . | . | . | . | . | . | |
|
|
|
. | 310 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | |
|
. | . | . | . | . | . | . | . | 350 | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | M | G | G | G | R | P | V | V | A | L | . |
. |
. |
. |
C | L | P | T | R | Y | L | H | A | N | S | . |
. |
. |
. |
. |
. |
G | M | I | S | K | A | D | Y | E | A | L | L | T | L | I | R | G | F | L | T | T | L | . |
. |
T | A | E | K | V | N | A | F | S | Q |
Query Conservation |   |
  |   |   |   |
|
|
|
|
|   |   | . | . | . | . |
|   |
|   |   |   |   |
|   |   |   | . | . | . | . | . | . |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
| . | . |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |
|   |   |
|
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
S | H | V | V | P | T | I | H | P | H | I | K | I | G | S | R | N | L | V | G | H | T | H | R | F | R | E | A | A | A | S | V | H | G | D | E | A | L | I | K | G | A | K | I | X | A | L | X | G | L | E | L | I | T | N | Q | D | V | Y | Q | D | I | I | E |
Template Known Secondary structure |   |
. | . | T | T | T | S |
| B |
|
|
|  |  |  |
| S |
| T | T |
|
| T | T | S |  |  |  |  |  |  |  | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
321 | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . |
  |