Job Description P18335 Confidence 99.96% Date Thu Jan 5 11:36:49 GMT 2012 Rank 89 Aligned Residues 340 % Identity 14% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.								.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.			.	100	.	.	.	.	.	.	.	.	.	110
Predicted Secondary structure																																				.	.	.	.	.	.	.																										.	.
Query SS confidence																																				.	.	.	.	.	.	.																										.	.
Query Sequence		Q	G	K	E	Y	V	D	F	A	G	G	I	A	V	T	A	L	G	H	C	H	P	A	L	V	N	A	L	K	T	Q	G	E	T	.	.	.	.	.	.	.	L	W	H	I	S	N	V	F	T	N	E	P	A	L	R	L	G	R	K	L	I	E	A	T	F	.	.	A	E	R	V	V	F	M	N	S	G	T	E
Query Conservation																																				.	.	.	.	.	.	.																										.	.
Alig confidence												.	.	.	.	.	.																			.	.	.	.	.	.	.																										.	.
Template Conservation												.	.	.	.	.	.
Template Sequence		E	N	A	I	Y	F	L	G	N	S	.	.	.	.	.	.	L	G	L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	E	K	E	I	A	L	M	N	A	L	T	V
Template Known Secondary structure			B					B	T	T	T	.	.	.	.	.	.	S			B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					T			G	G	G					S
Template Predicted Secondary structure												.	.	.	.	.	.
Template SS confidence
		66	.	.	.	70	.	.	.	.	.							.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.
		111	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.					160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.
Predicted Secondary structure																																																			.	.	.	.
Query SS confidence																																																			.	.	.	.
Query Sequence		A	N	E	T	A	F	K	L	A	R	H	Y	A	C	V	R	H	S	P	F	K	T	K	I	I	A	F	H	N	A	F	H	G	R	S	L	F	T	V	S	V	G	G	Q	P	K	Y	S	D	.	.	.	.	G	F	G	P	K	P	A	D	I	I	H	V	P	F	N	D	L	H	A	V	K	A	V	M	D	D	H
Query Conservation																																																			.	.	.	.
Alig confidence								.	.	.	.	.																																							.	.	.	.
Template Conservation								.	.	.	.	.
Template Sequence		N	L	H	L	L	M	.	.	.	.	.	L	S	F	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S
Template Known Secondary structure								.	.	.	.	.								S	S	S							T	T																T	T														T	T		S	S														G	G	G
Template Predicted Secondary structure								.	.	.	.	.
Template SS confidence
		140	.	.	.	.	.						.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.
		187	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260		.	.	.	.	.
Predicted Secondary structure																																																																												.
Query SS confidence																																																																												.
Query Sequence		T	C	A	V	V	V	E	P	I	Q	G	E	G	G	V	T	A	A	T	P	E	F	L	Q	G	L	R	E	L	C	D	Q	H	Q	A	L	L	V	F	D	E	V	Q	C	G	M	G	R	T	G	D	L	F	A	Y	M	H	Y	G	V	T	P	D	I	L	T	S	A	K	A	L	G	G	G	.	F	P	I	S	A
Query Conservation																																																																												.
Alig confidence																				.	.	.	.																						.	.	.																													.
Template Conservation																				.	.	.	.																						.	.	.
Template Sequence		I	A	V	I	L	F	S	G	V	H	F	Y	T	G	Q	H	F	N	.	.	.	.	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	.	.	.	A	V	G	N	V	E	L	Y	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G
Template Known Secondary structure									S	B		T	T	T		B	B			.	.	.	.											T	T								T	T	.	.	.	T	T	T	T	S								T								S	S	S	T	T				T	T
Template Predicted Secondary structure																				.	.	.	.																						.	.	.
Template SS confidence
		215	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.					.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.				.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.
		266	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.																										.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.				.	.	.	.	.	310	.	.	.	.	.	.	.
Predicted Secondary structure																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																						.	.	.
Query SS confidence																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																						.	.	.
Query Sequence		M	L	T	T	A	E	I	A	S	A	F	H	P	G	S	H	G	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	Y	G	G	N	P	L	A	C	A	V	A	G	A	A	F	D	I	I	N	T	.	.	.	P	E	V	L	E	G	I	Q	A	K	R	Q	R
Query Conservation																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																						.	.	.
Alig confidence																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																						.	.	.
Template Conservation
Template Sequence		A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T	G	Y
Template Known Secondary structure						G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S
Template Predicted Secondary structure
Template SS confidence
		288	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.
		318	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.			.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380		.	.	.	.	.	.	.	.	.	390	.	.	.	.
Predicted Secondary structure																		.	.																																																.
Query SS confidence																		.	.																																																.
Query Sequence		F	V	D	H	L	Q	K	I	D	Q	Q	Y	D	V	F	S	.	.	D	I	R	G	M	G	L	L	I	G	A	E	L	K	P	Q	Y	K	G	R	A	R	D	F	L	Y	A	G	A	E	A	G	V	M	V	L	N	A	G	P	D	V	M	R	F	A	P	.	S	L	V	V	E	D	A	D	I	D	E	G	M	Q
Query Conservation																		.	.																																																.
Alig confidence																		.	.																			.	.	.	.																										.
Template Conservation																																						.	.	.	.
Template Sequence		L	E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	P	N	K	.	.	.	.	D	V	F	Q	E	L	E	K	R	G	V	V	C	D	K	R	N	P	N	G	I	R	V	A	P	V	P	L	Y	N	S	F	H	D	V	Y	K	F	T	N
Template Known Secondary structure																	S		S	S	G	G	G	B		S									T	T		.	.	.	.								T	T	T							T	T	T					B			T	T	T
Template Predicted Secondary structure																																						.	.	.	.
Template SS confidence
		368	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.					.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.
		395	.	.	.	.	400	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	F	A	H	A	V	A
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	L	T	S	I	L	D
Template Known Secondary structure								T
Template Predicted Secondary structure
Template SS confidence
		453	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions