|   |
63 | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | |
|
. | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | |
|
|
|
. | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 130 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  | . | . | . | . |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
L | V | N | A | L | K | T | Q | G | E | T | L | W | H | I | S | N | V | F | T | . |
. |
N | E | P | A | L | R | L | G | R | K | L | I | E | A | T | F | A | E | R | . |
. |
. |
. |
V | V | F | M | N | S | G | T | E | A | N | E | T | A | F | K | L | A | R | H | Y | A | C | V | R | . |
. |
. |
. |
. |
H | S | P | F | K |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |   | . | . | . | . |   |   |   |   |   |
|
|
|   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
A | A | D | W | L | T | S | T | A | N | T | N | M | F | T | Y | E | I | A | P | V | F | V | L | L | E | Y | V | T | L | K | K | M | R | E | I | I | G | W | P | G | G | S | G | D | G | I | F | S | P | G | G | A | I | S | N | M | Y | A | M | M | I | A | R | F | K | M | F | P | E | V | K | E | K | G | M | A | A | L | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
| S | S |
| T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| G | G | G |
| S |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |  |
| G | G | G | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
192 | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . |
  |
  |   |
132 | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | K | I | I | A | F | H | N | A | F | H | G | R | S | L | F | T | V | S | V | G | G | Q | P | K | Y | S | D | G | F | G | P | K | P | A | D | I | I | H | V | P | F | N | D | L | H | A | V | K | A | V | M | D | D | H | T | . |
. |
. |
. |
. |
. |
C | A | V | V | V | E | P | I | Q | G | E | G | G | V | T | A | A | T |
Query Conservation |   |
  |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |
|   |   |
|   |   |   |
|   |
|   |   |
|
|   |   |   |
|
|
|
|   |   |   | . | . | . | . |
|   |   |
|   |   |
|   |   |
|   |
|
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |
|   |
|
|
|   |
|
|   |
|
|
| . |
Template Sequence |   |
R | L | I | A | F | T | S | E | H | S | H | F | S | L | K | K | G | A | A | A | L | G | I | G | T | D | S | . |
. |
. |
. |
V | I | L | I | K | C | D | E | R | G | K | M | I | P | S | D | L | E | R | R | I | L | E | A | K | Q | K | G | F | V | P | F | L | V | S | A | T | A | G | T | T | V | Y | G | A | F | D | P | . |
Template Known Secondary structure |   |
|  |  |  |  |  |  | T | T | S |
| T |  |  |  |  |  |  |  |  | T | T | S |
| G | G | G | . | . | . | . |  |  |  |  |
| B |
| T | T | S |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  | B | S |
| T | T | T |
|
| B |
|
| . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
272 | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | |
|
|
|
. | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | |
  |
  |   |
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | |
|
|
. | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | |
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| . | . | . |
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
Query Sequence |   |
P | E | F | L | Q | G | L | R | E | L | C | D | Q | H | Q | A | L | L | V | F | D | E | V | Q | C | G | M | G | R | T | G | D | L | F | A | Y | M | H | Y | G | V | . |
. |
. |
T | P | D | I | L | T | S | A | K | A | L | G | G | G | F | P | I | S | A | M | L | T | T | A | E | I | A | S | A | F | . |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
. | . | . |
|   |   |
|
|   |
|   |   |   |   |
|   |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|
|
|   |   |   |
|
| . |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
L | L | A | V | A | D | I | C | K | K | Y | K | I | W | M | H | V | D | A | A | W | G | G | G | L | L | M | S | R | K | H | K | W | K | L | S | G | V | E | R | A | N | S | V | T | W | N | P | H | M | . |
M | G | V | P | L | Q | C | S | A | L | L | V | R | E | E | G | L | M | Q | N | C | N | Q | M | H | D |
Template Known Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  | T | T | G | G | G | G | G | G |
| T | T | T | G | G | G | G | T | T | G | G | G |
| S |  |  |  |  |
|
|
|
| . |
|
|
| S | S |
|
|  |  |  |  |  | S | S | T | T |  |  |  |  |  |  |
|
|
|
|
Template Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|  |  | . |  |
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
347 | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | |
. | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . |
  |
  |   |
|
|
|
|
|
277 | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | |
Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . |
Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
. |
. |
. |
. |
. |
H | P | G | S | H | G | S | T | Y | G | G | N | P | L | A | C | A | V | A | G | A | A | F | D | I | I | N | T | P | E | V | L | E | G | I | Q | A | K | R | Q | R | F | V | D | H | L | Q | K | I | D | Q | Q | Y | D | V | F | S | D | I | R | G | M | G | L | L | I | G | A | E | L | K | P | Q | Y | . |
Query Conservation |   |
. | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   | . |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |
| . |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |
|   |   |   |
Template Sequence |   |
L | S | Y | D | T | G | D | K | A | L | Q | C | G | R | H | V | D | V | F | K | L | W | L | M | W | R | A | K | G | T | T | G | F | E | A | H | V | D | K | C | L | E | L | A | E | Y | L | Y | N | I | I | . |
K | N | R | E | G | Y | E | M | V | F | D | G | K | P | Q | H | T | N | V | C | F | W | Y | I | P | P | S | L |
Template Known Secondary structure |   |
G | G | G |
|
| G | G | G | S | S |
| S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  | T | S | T | T |  |  |  | S | S | S | S |
|
| S | S | S |
|  |  |  |  |  |
|
| T | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
435 | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | |
. | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
351 | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 370 | . | . | . | . | . | . | . | . | . | 380 | |
. | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  | . | . | . | . | . |  |  |
|
|
|
|  |  |  |  |  |  | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | G | R | A | R | D | F | L | Y | A | G | A | E | A | G | V | M | V | . |
. |
. |
. |
. |
L | N | A | G | P | D | V | M | R | F | A | P | . |
S | L | V | V | E | D | A | D | I | D | E | G | M | Q | R | F | A | H | A |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   | . | . | . | . | . |   |
|   |
|   |   |   |
|
|
|   |   | . |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |
|   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |
|
|   |   |
|   |   |
|
Template Sequence |   |
R | T | L | E | E | R | M | S | R | L | S | K | V | A | P | V | I | K | A | R | M | M | E | Y | G | T | T | M | V | S | Y | Q | P | L | G | D | K | V | N | F | F | R | M | V | I | S | N | P | A | A | T | H | Q | D | I | D | F | L | I | E | E | I | E | R | L |
Template Known Secondary structure |   |
T | T |
|
|
|
|  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
514 | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . |
  |