Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	A	L	T	P	F	S	A	A	P	T	G	P	P	S	P	A	P	R	S	K	P	C	P	S	T	L	I	A	A	W	V	R	K	M	R	V	S	W	L	E	S	K	C	D	T	P	F	A	N	N	L	S	F	I	S	S	G	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																																				?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	S	S	S	S	F	T	L	A	S	T	A	C	R	N	S	C	L	C	S	S	S	I	F	F	Q	V	L	R	R	N	C	S	S	N	C	C	S	I	S	N	V	D	I	S	L	S	A	F	S	F	N	R	F	E	T	S	S	K	M
Secondary structure
SS confidence
Disorder				?	?						?				?																																										?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	R	Y	N	L	P	C	P	R	S	L	L	A	I	L	S	P	P	K	C	C	N	S	P	A	I	S	C	Q	L	R	R	C	C	S	G	C	P	S	I	D	L	N	S	S	L	R	I	S	T	L	E	R	R	V	L	P	F	S	L
Secondary structure
SS confidence
Disorder																																											?						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.
Sequence		W	V	S	N	R	A	K	F	A	N	C	S	S	L	Q	C
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1bdt chain A Region: 118 - 135 Aligned: 18 Modelled: 18 Confidence: 20.3% Identity: 44% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 1b28 chain A Region: 118 - 135 Aligned: 18 Modelled: 18 Confidence: 19.4% Identity: 44% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 2wfu chain A Region: 73 - 94 Aligned: 16 Modelled: 22 Confidence: 14.5% Identity: 81% PDB header:signaling protein Chain: A: PDB Molecule:probable insulin-like peptide 5 a chain; PDBTitle: crystal structure of dilp5 variant db Phyre2 PDB 2wfv chain A Region: 73 - 94 Aligned: 16 Modelled: 22 Confidence: 14.0% Identity: 81% PDB header:signaling protein Chain: A: PDB Molecule:probable insulin-like peptide 5 a chain; PDBTitle: crystal structure of dilp5 variant c4 Phyre2 PDB 1myl chain A Region: 119 - 135 Aligned: 17 Modelled: 17 Confidence: 10.0% Identity: 41% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 1baz chain A Region: 118 - 135 Aligned: 18 Modelled: 18 Confidence: 8.8% Identity: 44% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 1myk chain A Region: 119 - 135 Aligned: 17 Modelled: 17 Confidence: 8.3% Identity: 41% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: Arc/Mnt-like phage repressors Phyre2 PDB 1xhj chain A Region: 146 - 162 Aligned: 17 Modelled: 17 Confidence: 7.8% Identity: 35% Fold: Alpha-lytic protease prodomain-like Superfamily: Fe-S cluster assembly (FSCA) domain-like Family: NifU C-terminal domain-like Phyre2 PDB 1veh chain A Region: 146 - 177 Aligned: 32 Modelled: 32 Confidence: 7.4% Identity: 22% Fold: Alpha-lytic protease prodomain-like Superfamily: Fe-S cluster assembly (FSCA) domain-like Family: NifU C-terminal domain-like Phyre2 PDB 3i3a chain C Region: 169 - 188 Aligned: 20 Modelled: 20 Confidence: 6.7% Identity: 20% PDB header:transferase Chain: C: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n- PDBTitle: structural basis for the sugar nucleotide and acyl chain2 selectivity of leptospira interrogans lpxa Phyre2 PDB 1th5 chain A domain 1 Region: 146 - 160 Aligned: 15 Modelled: 15 Confidence: 6.6% Identity: 7% Fold: Alpha-lytic protease prodomain-like Superfamily: Fe-S cluster assembly (FSCA) domain-like Family: NifU C-terminal domain-like Phyre2 PDB 1z2t chain A Region: 28 - 37 Aligned: 10 Modelled: 10 Confidence: 6.4% Identity: 50% PDB header:lipid binding protein Chain: A: PDB Molecule:anchor peptide ser65-leu87 of almgs; PDBTitle: nmr structure study of anchor peptide ser65-leu87 of enzyme2 acholeplasma laidlawii monoglycosyldiacyl glycerol3 synthase (almgs) in dhpc micelles Phyre2 PDB 2jnv chain A Region: 146 - 162 Aligned: 17 Modelled: 17 Confidence: 6.3% Identity: 29% PDB header:metal transport Chain: A: PDB Molecule:nifu-like protein 1, chloroplast; PDBTitle: solution structure of c-terminal domain of nifu-like2 protein from oryza sativa Phyre2 PDB 1n12 chain A Region: 97 - 128 Aligned: 32 Modelled: 32 Confidence: 6.2% Identity: 22% Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily: Bacterial adhesins Family: Pilus subunits Phyre2 PDB 2h8b chain B Region: 15 - 34 Aligned: 20 Modelled: 20 Confidence: 6.1% Identity: 40% PDB header:hormone/growth factor Chain: B: PDB Molecule:insulin-like 3; PDBTitle: solution structure of insl3 Phyre2 1 d1bdta_ 2 d1b28a_ 3 c2wfuA_ 4 c2wfvA_ 5 d1myla_ 6 d1baza_ 7 d1myka_ 8 d1xhja_ 9 d1veha_ 10 c3i3aC_ 11 d1th5a1 12 c1z2tA_ 13 c2jnvA_ 14 d1n12a_ 15 c2h8bB_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1bdta_ 20.3 44 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 2 d1b28a_ 19.4 44 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 3 c2wfuA_ 14.5 81 PDB header:signaling protein Chain: A: PDB Molecule:probable insulin-like peptide 5 a chain; PDBTitle: crystal structure of dilp5 variant db 4 c2wfvA_ 14.0 81 PDB header:signaling protein Chain: A: PDB Molecule:probable insulin-like peptide 5 a chain; PDBTitle: crystal structure of dilp5 variant c4 5 d1myla_ 10.0 41 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 6 d1baza_ 8.8 44 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 7 d1myka_ 8.3 41 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 8 d1xhja_ 7.8 35 Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:NifU C-terminal domain-like 9 d1veha_ 7.4 22 Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:NifU C-terminal domain-like 10 c3i3aC_ 6.7 20 PDB header:transferase Chain: C: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n- PDBTitle: structural basis for the sugar nucleotide and acyl chain2 selectivity of leptospira interrogans lpxa 11 d1th5a1 6.6 7 Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:NifU C-terminal domain-like 12 c1z2tA_ 6.4 50 PDB header:lipid binding protein Chain: A: PDB Molecule:anchor peptide ser65-leu87 of almgs; PDBTitle: nmr structure study of anchor peptide ser65-leu87 of enzyme2 acholeplasma laidlawii monoglycosyldiacyl glycerol3 synthase (almgs) in dhpc micelles 13 c2jnvA_ 6.3 29 PDB header:metal transport Chain: A: PDB Molecule:nifu-like protein 1, chloroplast; PDBTitle: solution structure of c-terminal domain of nifu-like2 protein from oryza sativa 14 d1n12a_ 6.2 22 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:Bacterial adhesins Family:Pilus subunits 15 c2h8bB_ 6.1 40 PDB header:hormone/growth factor Chain: B: PDB Molecule:insulin-like 3; PDBTitle: solution structure of insl3

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0