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Job DescriptionP22256
Confidence99.95%DateThu Jan 5 11:38:48 GMT 2012
Rank91Aligned Residues347
% Identity16%Templatec3e9kA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex
Resolution1.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   3940.........50.........60.........70... ......80.........90.........100.........110..
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Query Sequence  EGREYLDFAGGIAVLNTGHLHPKVVAAVEAQLKKL. . . . . . SHTCFQVLAYEPYLELCEIMNQKVPGDFAKKTLLVTTGS
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Template Sequence  ENAIYFLGNS. . . . . . LGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGAN. EKEIALMNALT
Template Known Secondary structure 
B

BTTT......S

B
TTGGGGGTSSSS
GGGTTGGGT

.GGG
S
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   66...70..... ....80.........90.........100.........110.........120....... ..130........
 
   113......120.........130.........140.........150.........160.........170.........180.........190..
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Query Sequence  EAVENAVKIARAATKRSGTIAFSGAYHGRTHYTLALTGKVNPYSAGMGLMPGHVYRALYPCPLHGISEDDAIASIHRIFK
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Template Sequence  VNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQ. . . . . . LQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEG
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SSS
TT

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TT
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G
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   139140.........150.........160.........170..... ....180.........190.........200.........210..
 
   193......200.........210.........220.........230.........240.........250.........260.........270 .
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Query Sequence  NDAAPEDIAAIVIEPVQGEGGFYASSPAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAPDLTTFAKSI. A
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Template Sequence  . . . . . DSIAVILFSGVHFYTGQHFN. . . . IPAITKAGQAKGCYVGFDLAHAVGNVELY. . . LHDWGVDFACWCSYKYLNA
Template Known Secondary structure  .....GGSB
TTT
BB

....TT

TTTTTTS


...T


SSSTT

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   213......220.........230.. .......240.........250.........260. ........270.........280
 
   272.......280.........290....... ..300.........310.........320.......
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Query Sequence  GGFPLAGVTGRAEVMDAVAPGGLGGT. . . . . . . . . . . . . . . . . . . . . . . . YAGNPIACVAALEVLKVFEQENLLQKANDL
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Template Sequence  GAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK
Template Known Secondary structure 
TT



GGGTTTS

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GGGB
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B
SSGGGG

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   281........290.........300.........310.........320.........330.........340.........350.........360
 
   328.330.........340........ .350.........360.........370.........380.........390.........400.
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Query Sequence  GQKLKDGLLAIAEKHPEIGDV. . . . . . RGLGAMIAIELFEDGDHNKPDAKLTAEIVARARDKGLILLSCGPYYNVLRILV
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Template Sequence  SVLLTGYLEYLIKHNYGVVNIITPSHVEERGCQLTITFSVPNK. . . . . . . . . . DVFQELEKRGVVCDKRN. . PNGIRVAP
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S
SSGGGB
S


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   361........370.........380.........390.........400... ......410.........420 ........
 
   402.......410.........420..
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Query Sequence  . PLTIEDAQIRQGLEIISQCFD
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Template Sequence  VPLYNSFHDVYKFTNLLTSILD
Template Known Secondary structure 
TTT

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   438.440.........450.........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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