|   |
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | R | T | I | D | R | I | E | S | F | F | G | E | L | G | F | T | V | A | T | G | P | E | I | E | D | D | Y | H | N | F | D | A | L | N | I | P | G | H | H | P | A | R | A | D | H | D | T | F | W | F | D | T | T | R | L | L | R | T | Q | T | S | G | V | Q | I | R | T | M | K | A | Q | Q | P | P | I | R | I | I | A |
Query Conservation |   |
  |   |
|   |   |   |
|
|   |
|
|   |   |
|
|
|   |
|   |
|
|
|
|
|
|
|   |   |   |
|
|
|
|
|   |   |
|   |   |
|
|
|
|
|   |   |
|
|
|
|
|   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |
|   |
|   |   |   |   |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |
|
|   |
|
|   |   |   |   |
|   |
|
|   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|   |
| . | . | . | . | . | . | . | . |   |
|   |   |   |
|   |   | . | . |
|
|
|
|
Template Sequence |   |
A | A | L | V | R | G | F | R | R | Y | L | D | R | Q | D | F | T | E | I | F | T | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | Q | L | Y | K | . |
. |
. |
. |
. |
. |
. |
. |
Q | I | M | V | G | V | F | E | . |
. |
R | V | Y | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | S | . | . |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
| . | . |
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
129 | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | 160 | . | . | . | |
|
. | . | . | . |
  |
  |   |
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
P | G | R | V | Y | R | N | D | Y | D | Q | T | H | T | P | M | F | H | Q | M | E | G | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|   |
|
|
|   |
|   |
|   |
|
|   |   |   |
|   |
|   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|   |   |
Template Sequence |   |
V | A | P | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | Y | L | S | L | D | V | E | M | G | F | I | A | D | E | E | D | L | M | R | L | E | E | A | L | L | A | E | M | L | E | E | A | L | N | T | A | G | D | E | I | R | L | L | G | A | T | W | P | S | F | P | Q | D | I | P | R | L | T | H | A | E | A | K | R |
Template Known Secondary structure |   |
 |  |  |
| . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  | S |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |  |  |  |  | T | T |
|
|
|
|
|
| S | S | S |
|
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
196 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
213 | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | |
. | . | . | . | 250 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | |
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
I | V | D | T | N | I | S | F | T | N | L | K | G | T | L | H | D | F | L | R | N | F | F | E | E | D | L | Q | I | R | F | R | P | . |
S | Y | F | P | F | T | E | P | S | A | E | . |
. |
. |
. |
. |
. |
V | D | V | M | G | K | N | G | K | W | L | E | V | L | G | C | G | M | . |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
| . |   |
|
|
|
|
|
|
|
|   |
| . | . | . | . | . | . |   |
|
|   |   |   |   |   |   |
|
|
|
|   |
|   |
|   | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
| . | . | . |   |
|
|   |   |
|   |   |
|   |   |
Template Sequence |   |
I | L | K | E | E | L | G | Y | P | V | G | Q | D | L | S | E | E | A | E | R | L | L | G | E | Y | A | K | E | R | W | G | S | D | W | L | F | V | T | R | Y | P | R | S | V | R | P | F | Y | T | Y | P | E | E | D | G | T | T | R | S | F | D | L | L | F | R | G | . |
. |
. |
L | E | I | T | S | G | G | Q | R | I | H |
Template Known Secondary structure |   |
 |  |  |  | T | S |
|
|
|
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| S |  |  |  |  |  |
|
| B | G | G | G | S |
| T | T | B |
| B |
| T | T | S | B | B | S |  |  |  |  |  |  | T | T | . | . | . |  |  |  |  |  |  |  |  | B |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . |  |  |  |  |
|  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
278 | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | |
|
|
. | . | . | . | . | . | 350 | . | . | . | . |
  |
  |   |
|
|
|
275 | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
V | H | P | N | V | L | R | N | V | G | I | D | P | E | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | S | G | F | A | F | G | M | G | M | E | R | L | T | M | L | R | Y | G | V | T | D | L | R | S |
Query Conservation |   |
. | . | . |   |   |
|   |
|
|   |   |   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |
|
|
|   |
|
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |
|
|   |   |
| . | . |   |
|
|
|
|
|
|
|   |
|   |
|   |
|   |   |   |
|
|
|
Template Sequence |   |
R | Y | E | E | L | L | E | S | L | K | A | K | G | M | D | P | E | A | F | H | G | Y | L | E | V | F | K | Y | G | M | P | P | H | G | G | . |
. |
F | A | I | G | A | E | R | L | T | Q | K | L | L | G | L | P | N | V | R | Y |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
| G | G | G | G |  |  |  |  | G | G | G | G | S |
|
|
| S |  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S | G | G | G |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  | . | . |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
355 | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | |
|
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . |
  |