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Job DescriptionP10443
Confidence100.00%DateThu Jan 5 11:32:19 GMT 2012
Rank1Aligned Residues1084
% Identity42%Templatec3e0dA_
PDB info PDB header:transferase/dnaChain: A: PDB Molecule:dna polymerase iii subunit alpha; PDBTitle: insights into the replisome from the crystral structure of2 the ternary complex of the eubacterial dna polymerase iii3 alpha-subunit
Resolution4.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1........10.........20.........30....... ..40.........50.........60.........70......
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Query Sequence  MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMP. . ALAITDFTNLCGLVKFYGAGHGAGIKPIVGADFNVQCDL. .
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Template Sequence  LK. . . FAHLHQHTQFSLLNGAAKLQDLLKWVKETTPEDPALAMTDHGNLFGAVEFYKKATAMGVKPIIGYEAYVAAESRF
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SB

TTSTTT





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TTTTT
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   5. ...10.........20.........30.........40.........50.........60.........70.........80.
 
   77..80.........90.........100.........110.........120.........130.........140.........150....
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Query Sequence  . . LGDELTHLTVLAANNTGYQNLTLLISKAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDEC
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Template Sequence  DRKRGGYFHLTLLAKDFTGYQNLVRLASRAYLEGF. YEKPRIDREILREHAQGLIALSGCLGAEIPQFILQDRLDLAEAR
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ST
B.SSSB
T
TT

STTBTT
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   82.......90.........100.........110...... ...120.........130.........140.........150.........160
 
   155....160.........170.........180.........190.........200.........210.........220.........230....
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Query Sequence  VAFYEEHFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVAIHDGFTLDDPKRPRNY
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Template Sequence  LNEDLSIFGDRFFIEIQNHGLPEQKKVNQVLKEFARKYGLGMVATNNGHYVRKEDARAHEVLLAIQSKTTLDDPERWRFP
Template Known Secondary structure  GGG

SS
TT




BSBSSGGGTT

SS
SS



S
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   166...170.........180.........190.........200.........210.........220.........230.........240.....
 
   235....240.........250.... .....260.........270.........280.. .... ...290.........300.........
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Query Sequence  SPQQYMRSEEEMCELFADIP. . . EALANTVEIAKRCNVTVRLGEYFLPQFP. TGDM. STEDYLVKRAKEGLEERLAFLFP
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Template Sequence  CDEFYVKTPEEMRAMLPEAEWGDEPFDNTVEIARMCDVDLPIGDKMVYRIPRFPLGRTEAQYLRELTFLGLLRRYPDRIT
Template Known Secondary structure  SS

B


S

ST






TTS


B









TTTS
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   246...250.........260.........270.........280.........290.........300.........310.........320.....
 
   310 .........320.........330.........340.........350.........360
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Query Sequence  D. . . . . . . . . . . . . . . . . . . . . . . . . . . . . EEERLKRRPEYDERLETELQVINQMGFPGYFLIVMEFIQWSKDNGVPVGP
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Template Sequence  EAFYREVLRLLDERALAEALARVEEKAWEELRKREWTAEAILHRALYELSVIERMGFPGYFLIVQDYINWARGHGVSVGP
Template Known Secondary structure  TT



TTTTT



T
TTT

B
S
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   328.330.........340.........350.........360.........370.........380.........390.........400.......
 
   361........370.........380.........390.........400.........410.........420.........430.........440
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Query Sequence  GRGSGAGSLVAYALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKA
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Template Sequence  GRGSAAGSLVAYAVGITNIDPLRFGLLFERFLNPERVSMPDIDTDFSDRERDRVIQYVRERYGEDKVAQIGTFGSLASKA
Template Known Secondary structure 

GGGGG
TTS

S
TTTTT

S
TTS





TTT
TTT



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   423......430.........440.........450.........460.........470.........480.........490.........500..
 
   441........450.........460........ .470.........480.........490.........500.........510........
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Query Sequence  VIRDVGRVLGHPYGFVDRISKLIPPDPG. . MTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNAGKHAGGVVIA
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Template Sequence  ALKDVARVYGIPHKKAEELAKLIPVQFGKPKPLQEAFEAEPELRAEMEKDERIRQVIEVAMRLEGLNRHASVHAAGVVIA
Template Known Secondary structure  TT

TTS
BSSSSB

TTTTTSS
TTTTT
STT







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   503......510.........520.........530.........540.........550.........560.........570.........580..
 
   519520.........530.........540.........550.........560.........570.........580.........590........
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Query Sequence  PTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIINWALEMINKRRAKNGEPPLDIAAIPLDDKKSFD
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Template Sequence  AEPLTDLVPLMRDQEG. RPVTQYDMGAVEALGLLKMDFLGLRTLTFLDEARRIVKESKGVE. . . . LDYDRLPLDDPKTFE
Template Known Secondary structure  SS
GGGTS

TT
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TTTB


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GGG

TT
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   583......590........ .600.........610.........620.........630.........640.. .......650.......
 
   599600.........610.........620.........630.........640.........650.........660.........670........
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Query Sequence  MLQRSETTAVFQLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLE
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Template Sequence  LLSRGETKGVFQLESGGMTATVRGLKPRRLEDIIALVSLYRPGPME. . HIPTYIRRHHGQEPVSYAEFPHAEKYLRPILD
Template Known Secondary structure  TT

TT
TT

S


S
STTGGG..TT
S



TTSTTTG
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   658.660.........670.........680.........690.........700... ......710.........720.........730.....
 
   679680.........690.........700.........710.........720.........730.........740.........750........
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Query Sequence  PTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAELAMKIFDLVEKFAGYGFNK
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Template Sequence  ETYGIPVYQEQIMQIASQVAGYSLGEADLLRRAMGKKRVEEMQKHRERFVRGAKERGVPEEEANRLFDMLEAFANYGFNK
Template Known Secondary structure  GGTT


SS


T
TTTS

STT



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   736...740.........750.........760.........770.........780.........790.........800.........810.....
 
   759760.........770.........780.........790.........800.........810.........820.........830........
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Query Sequence  SHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVVGLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAI
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Template Sequence  SHAAAYSLLSYQTAYVKAHYPVEFMAALLSVERHDSDKVAEYIRDARALGIPVLPPDVNRSGFDFKVVGEE. ILFGLSAV
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TTT
TTS




TTT

SS
TT.

STTS
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   816...820.........830.........840.........850.........860.........870.........880...... ...890....
 
   839840.........850.........860.........870.........880.........890.........900.........910........
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Query Sequence  KGVGEGPIEAIIEARNKGGYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAKAEAI
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Template Sequence  KNVGEMAARAILEERERGGPFKSLGDFLKRLPEQVVNKRALESLVKAGALDAFG. DRARLLASLEPLLRWAAETRERGRS
Template Known Secondary structure  SS

S
S

SS
TTTS
TTTGGGS.
TT
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   895....900.........910.........920.........930.........940........ .950.........960.........970...
 
   919920.........930.........940.........950.........960.........970.........980 .........990......
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Query Sequence  GQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKEIERYVGGV. . RLKDMHPTERGKVITA
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Template Sequence  GLVGLFA. . . . . . EVEEPPLVEASPLDEITMLRYEKEALGIYVSGHPVLRYPGLREVASCTIEELSEFVRELPGKPKVLL
Template Known Secondary structure 


SSSS......













SS

S

GGGT
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GGGSSSSSS
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   974.....980 .........990.........1000.........1010.........1020.........1030.........1040.......
 
   997..1000.........1010.........1020.........1030.........1040.........1050.........1060.........1070......
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Query Sequence  AGLVVAARVMVTKRGNRIGICTLDDRSGRLEVMLFTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEA
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Template Sequence  SGMVE. . . . . . . . . . . . EVRFTLSDETGALEVVKE. . . . . . . . . . . . . DIPLLVLAEVE. . . . . . . . RVLAQAVWTLEEV
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TT

T.............T

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   1048.1050.. .......1060.........1070 .........1080. ........1090....
 
   1077..1080.........1090.........1100.........1110.........1120.........1130.........1140
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Query Sequence  REKYARGLAISLTDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSD
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Template Sequence  LEA. PKALEVEVDHALLDE. KGARLKSLLDEH. PGSLPVYLRVLGPFGEALFAL. REVRVGEEA
Template Known Secondary structure  TTS.



S


TT.T

TS.
SSS.
ST
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   1125.. ..1130.........1140.. .......1150.... .....1160.........1170..... ....1180....
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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