|   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
T | T | F | A | D | L | G | L | K | A | P | I | L | E | A | L | N | D | L | G | Y | E | K | P | S | P | I | Q | A | E | C | I | P | H | L | L | N | G | R | D | V | L | G | M | A | Q | T | G | S | G | K | T | A | A | F | S | L | P | L | L | Q | N | L | D | P | E | L | . |
. |
. |
. |
. |
K | A | P | Q | I | L | V | L |
Query Conservation |   |
  |   |
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   | . | . | . | . | . |   |   |   |   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
Template Sequence |   |
Q | H | F | T | S | A | D | L | R | D | I | I | I | D | N | V | N | K | S | G | Y | K | I | P | T | P | I | Q | K | C | S | I | P | V | I | S | S | G | R | D | L | M | A | C | A | Q | T | G | S | G | K | T | A | A | F | L | L | P | I | L | S | K | L | L | E | D | P | H | E | L | E | L | G | R | P | Q | V | V | I | V |
Template Known Secondary structure |   |
S | S | T | T | S | S |
|
|
|  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
| B | T | T | B |
| S |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
Predicted Secondary structure |   |
 |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | P | T | R | E | L | A | V | Q | V | A | E | A | M | T | D | F | S | K | H | M | R | G | V | N | V | V | A | L | Y | G | G | Q | R | Y | D | V | Q | L | R | A | L | R | Q | G | P | Q | I | V | V | G | T | P | G | R | L | L | D | H | L | K | R | G | T | L | D | L | S | K | L | S | G | L | V | L | D | E | A | D | E |
Query Conservation |   |
  |
|
|   |   |
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
S | P | T | R | E | L | A | I | Q | I | F | N | E | A | R | K | F | A | F | E | S | . |
Y | L | K | I | G | I | V | Y | G | G | T | S | F | R | H | Q | N | E | C | I | T | R | G | C | H | V | V | I | A | T | P | G | R | L | L | D | F | V | D | R | T | F | I | T | F | E | D | T | R | F | V | V | L | D | E | A | D | R |
Template Known Secondary structure |   |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S | . | S |
|
|  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  |  |  | T |
|
| S |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | S | S |
|
| T | T |
|
|  |  |  |  |  | T |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
325 | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | |
. | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . |
  |
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | L | R | M | G | F | I | E | D | V | E | T | I | M | A | . |
. |
Q | I | P | E | G | H | Q | T | A | L | F | S | A | T | M | P | E | A | I | R | R | I | T | R | R | F | M | K | E | P | Q | E | V | R | I | Q | S | S | V | T | T | R | P | D | I | S | Q | S | Y | W | T | V | W | G | M | R | K | N | E | A | L | V | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
M | L | D | M | G | F | S | E | D | M | R | R | I | M | T | H | V | T | M | R | P | E | H | Q | T | L | M | F | S | A | T | F | P | E | E | I | Q | R | M | A | G | E | F | L | K | N | Y | V | F | V | A | I | G | I | V | G | G | A | C | S | D | V | K | Q | T | I | Y | E | V | N | K | Y | A | K | R | S | K | L | I | E |
Template Known Secondary structure |   |
 | T | S |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T | S |
| S | S |
|  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  | G | G | G |
| S | S |
|  |  |  |  |  | S | S | T | T |
|
|
| T | T |  |  |  |  |  |  |  |
|
| G | G | G |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
404 | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . |
  |
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | L | E | A | E | D | F | D | A | A | I | I | F | V | R | T | K | N | A | T | L | E | V | A | E | A | L | E | R | N | G | Y | N | S | A | A | L | N | G | D | M | N | Q | A | L | R | E | Q | T | L | E | R | L | K | D | G | R | L | D | I | L | I | A | T | D | V | A | A | R | G | L | D | V | E | R | I | S | L | V | V |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|
|
|
|   |   |
|   |   |
|
|
|
|
|   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|
|
|
|   |   |   |   |   |
|
|
|
|
|   |
|   |   |
|
|
Template Sequence |   |
I | L | S | E | Q | A | D | . |
G | T | I | V | F | V | E | T | K | R | G | A | D | F | L | A | S | F | L | S | E | K | E | F | P | T | T | S | I | H | G | D | R | L | Q | S | Q | R | E | Q | A | L | R | D | F | K | N | G | S | M | K | V | L | I | A | T | S | V | A | S | R | G | L | D | I | K | N | I | K | H | V | I |
Template Known Secondary structure |   |
 |  |  |  |
|
| T | . | T |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|  |  |  |  |
| G | G | G | S | S | S |
|
|
| T | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
| . |
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
484 | . | . | . | . | . | 490 | |
. | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . |
  |
  |   |
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | |
. | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | Y | D | I | P | M | D | S | E | S | Y | V | H | R | I | G | R | T | G | R | A | G | R | A | G | R | A | L | L | F | V | E | . |
N | R | E | R | R | L | L | R | N | I | E | R | T | M | K | L | T | I | P | E | V | E |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |
|   |   |
|   |
|
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |
|
|
|   |
|
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
Template Sequence |   |
N | Y | D | M | P | S | K | I | D | D | Y | V | H | R | I | G | R | T | G | R | V | G | N | N | G | R | A | T | S | F | F | D | P | E | K | D | R | A | I | A | A | D | L | V | K | I | L | E | G | S | G | Q | T | V | P |
Template Known Secondary structure |   |
 | S | S |
|
| S | S |  |  |  |  |  |  |  |  | T | T | S | S |
| T | T |
|
|  |  |  |  |  |  |  |
| T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
563 | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . |
  |