|   |
37 | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | |
|
. | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | |
|
|
|
. | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | G | K | E | Y | I | D | F | A | G | G | I | A | V | N | A | L | G | H | A | H | P | E | L | R | E | A | L | N | E | Q | A | S | K | . |
. |
F | W | H | T | G | N | G | Y | T | N | E | P | V | L | R | L | A | K | K | L | I | D | A | . |
. |
. |
. |
T | F | A | D | R | V | F | F | C | N | S | G | A | E | A | N | E |
Query Conservation |   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |   |   |
|   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   | . | . | . | . |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |
|   |   |   | . | . |   |   |   |   |   |   | . |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|
|   |
Template Sequence |   |
K | G | E | D | V | I | N | L | T | A | G | . |
. |
E | P | D | F | P | T | . |
P | E | P | V | V | E | E | A | V | R | F | L | Q | K | G | E | V | K | Y | T | D | P | R | G | I | Y | E | L | R | E | G | I | A | K | R | I | G | E | R | Y | K | K | D | I | S | P | D | Q | V | V | V | T | N | G | A | K | Q | A | L | F |
Template Known Secondary structure |   |
T | T |
|
|
|  |  |
|
|
| S | . | . | S |
| S | S |
|
| . |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
| G | G | G |  |  |  |  | S |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|
| . | . |
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
27 | . | . | 30 | . | . | . | . | . | . | . | |
|
. | . | 40 | . | . | . | |
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . |
  |
  |   |
111 | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | L | K | L | A | R | K | F | A | H | D | R | Y | G | S | H | K | S | G | I | V | A | F | K | N | A | F | H | G | R | T | L | F | T | V | S | A | G | G | Q | P | A | Y | S | Q | D | F | A | P | L | P | A | D | I | R | H | A | A | Y | N | D | I | N | S | A | S | A | L | I | D | D | S | T | C | A | V | I | V | E |
Query Conservation |   |
  |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
N | A | F | M | A | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
L | D | P | G | D | E | V | I | V | F | S | P | V | W | V | S | Y | I | P | Q | I | I | L | A | G | G | T | V | N | V | . |
. |
. |
. |
. |
V | E | T | F | M | S | K | N | F | Q | P | S | L | E | E | V | E | G | L | L | V | G | K | T | K | A | V | L | I | N |
Template Known Secondary structure |   |
 |  |  |  |  |  | . | . | . | . | . | . | . | . | . |
|
| T | T |
|  |  |  |  |  |  | S |
|
| T | T |  |  |  |  |  |  |  | T | T |
|  |  |  |  | . | . | . | . | . |  |  |
|
| G | G | G | T | T |
|
|
|  |  |  |  |  |  | T |
|
| T | T |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
104 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . |
  |
  |   |
191 | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | |
|
|
|
. | . | . | 250 | . | . | . | . | . | |
. | . | . | . | 260 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
| . | . | . | . |  |  |  |
|
|
|  |  |
| . |
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | I | Q | G | E | G | G | V | V | P | A | S | N | A | F | L | Q | G | L | R | E | L | C | N | R | H | N | A | L | L | I | F | D | E | V | Q | T | G | V | G | R | T | G | E | L | Y | A | Y | M | H | Y | G | V | T | P | D | . |
. |
. |
. |
L | L | T | T | A | K | A | L | G | . |
G | G | F | P | V | G | A | L | L | A |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
| . | . | . | . |
|   |
|   |
|
|   |   |   | . |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|
| . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |
Template Sequence |   |
S | P | N | N | P | T | G | . |
V | V | Y | R | R | E | F | L | E | G | L | V | R | L | A | K | K | R | N | F | Y | I | I | S | D | E | V | Y | D | S | L | V | Y | T | D | E | F | T | S | I | L | D | V | S | E | G | F | D | R | I | V | Y | I | N | G | F | S | K | S | H | S | M | T | G | W | R | V | G | Y | L | I | S |
Template Known Secondary structure |   |
S | S |
| T | T | T |
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
| T | T | T | T | S | B |
| S | S |
|
|
|
|  |  |  |  |
| S | S | S | T | T |  |  |  |  |  |  | S | T | T | T | T | T |
| G | G | G |
|
|  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
170 | . | . | . | . | . | . | |
. | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . |
  |
  |   |
266 | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | E | E | C | A | R | V | M | T | V | G | T | H | G | T | T | Y | G | G | N | P | L | A | S | A | V | A | G | K | V | L | E | L | I | N | T | P | E | M | L | N | G | V | K | Q | R | H | D | W | F | V | E | R | L | N | T | I | N | H | R | Y | G | L | F | S | E | V | R | G | L | G | L | L | I | G | C | V | L | N | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   | . | . |
Template Sequence |   |
S | E | K | V | A | T | A | V | S | K | I | Q | S | H | T | T | S | C | I | N | T | V | A | Q | Y | A | A | L | K | A | L | . |
. |
. |
. |
. |
E | V | D | N | S | Y | M | V | Q | T | F | K | E | R | K | N | F | V | V | E | R | L | K | K | M | G | V | K | F | V | E | P | E | G | A | F | Y | L | F | F | K | V | . |
. |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
|
|  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
| S | B | S | S |  |  |  |  |  |
| . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
| . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
249 | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | |
|
  |
  |   |
346 | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | |
|
|
|
. | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | Y | A | G | Q | A | K | Q | I | S | Q | E | A | A | K | A | G | V | M | V | L | I | A | . |
. |
. |
. |
G | G | N | V | V | R | F | A | P | A | L | N | V | S | E | E | E | V | T | T | G | L | D | R | F | A | A | A | C | E |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |
|   |
|   |
|
|   |   |   |
|   | . | . | . | . |
|   |   |   |
|
|
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |
|   |   |
|
|   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |
|
|
| . | . |
|   |   |   |   |   |
|   |
|   |   |
|
|   |
|
|   |   |   |
|   |
Template Sequence |   |
. |
R | G | D | D | V | K | F | C | E | R | L | L | E | E | K | K | V | A | L | V | P | G | S | A | F | L | K | P | G | F | V | R | L | . |
. |
S | F | A | T | S | I | E | R | L | T | E | A | L | D | R | I | E | D | F | L | N |
Template Known Secondary structure |   |
. | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|  |  | G | G | G | G | T |
| T | T |  |  |  |  | . | . |  |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
. |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
322 | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | |
|
. | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . |
  |