|   |
41 | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | |
|
. | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | |
|
|
|
. | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | I | D | F | A | G | G | I | A | V | N | A | L | G | H | A | H | P | E | L | R | E | A | L | N | E | Q | A | S | K | . |
. |
F | W | H | T | G | N | G | Y | T | N | E | P | V | L | R | L | A | K | K | L | I | D | A | T | F | . |
. |
. |
. |
A | D | R | V | F | F | C | N | S | G | A | E | A | N | E | A | A | L | K |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |   |   |
|   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   | . | . | . | . |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |   |
|   |   |   |   |   |   | . | . | . |
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
L | L | P | F | T | I | S | D | M | D | F | A | T | . |
. |
. |
A | P | C | I | I | E | A | L | N | Q | R | L | M | H | G | V | F | G | Y | S | R | W | K | N | . |
D | E | F | L | A | A | I | A | H | W | F | S | T | Q | H | Y | T | A | I | D | S | Q | T | V | V | Y | G | P | S | V | I | Y | M | V | S | E | L | I | R |
Template Known Secondary structure |   |
|  |  |
|
| S | S | S |
| S | S |
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|
| S |
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
| G | G | G |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | |
. | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . |
  |
  |   |
115 | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | R | K | F | A | H | D | R | Y | G | S | H | K | S | G | I | V | A | F | K | N | A | F | H | G | R | T | L | F | T | V | S | A | G | G | Q | P | A | Y | S | Q | D | F | A | P | L | P | A | D | I | R | H | A | A | Y | N | D | I | N | S | A | S | A | L | I | D | D | S | T | C | A | V | I | V | E | P | I | Q | G |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
Alig confidence |   |
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . | . | . | . | . | . | . |   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
W | S | E | T | G | E | G | V | V | I | H | T | P | A | Y | D | A | F | Y | K | A | I | E | G | N | Q | R | T | V | M | P | V | A | L | E | K | Q | A | D | G | W | . |
. |
. |
. |
F | C | D | M | G | K | L | E | A | V | L | A | K | P | E | C | K | I | M | L | L | C | S | P | Q |
Template Known Secondary structure |   |
 | . | . | . | . | . | . | . | . | . | S | S |
| T | T |
|  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
|  |  |
| S | S | S |  | . | . | . | . |  |
|
|  |  |  |  |  |  |  |  | T | S | T | T |  |  |  |  |  |  |  | S | S |
|
Template Predicted Secondary structure |   |
 | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
106 | |
|
|
|
|
|
|
|
|
. | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | |
|
|
|
. | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . |
  |
  |   |
195 | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | |
|
|
. | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | |
. | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|  |  |
| . |
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | G | G | V | V | P | A | S | N | A | F | L | Q | G | L | R | E | L | C | N | R | H | N | A | L | L | I | F | D | E | V | Q | T | G | V | G | R | T | G | E | L | Y | . |
. |
. |
A | Y | M | H | Y | G | V | T | P | D | L | L | T | T | A | K | A | L | G | . |
G | G | F | P | V | G | A | L | L | A | T | E | E | C | A |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|
|   |   |   |   |
|   |   |
|   |   |   | . | . | . |
|   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |   |   | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
N | P | T | G | K | V | W | T | C | D | E | L | E | I | M | A | D | L | C | E | R | H | G | V | R | V | I | S | D | E | I | H | M | D | M | V | W | G | E | Q | P | H | I | P | W | S | N | V | A | R | G | D | W | A | L | L | T | S | G | S | K | S | F | N | I | P | A | L | T | G | A | Y | G | I | I | E | N | S | S | S |
Template Known Secondary structure |   |
T | T | T |
|
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| T | T | T | T |
| B |
| S | S | S |
|
|
|
| G | G | G | T |
|
| S | S |  |  |  |  |  |
| S |  |  |  |  | T |
| G | G | G |
|
|  |  |  |  |  |
| S |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
173 | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
  |
  |   |
271 | . | |
|
. | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | V | . |
. |
M | T | V | G | T | H | G | T | T | Y | G | G | N | P | L | A | S | A | V | A | G | K | V | L | E | L | I | N | T | P | E | M | L | N | G | V | K | Q | R | H | D | W | F | V | E | R | L | N | T | I | N | H | R | Y | G | L | F | S | E | V | R | G | L | G | L | L | I | G | C | V | L | N | A | D | Y | A |
Query Conservation |   |
  |   | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
R | D | A | Y | L | S | A | L | K | G | R | D | G | L | S | S | P | S | V | L | A | L | T | A | H | I | A | A | Y | Q | Q | G | A | P | W | L | D | A | L | R | I | Y | L | K | D | N | L | T | Y | I | A | D | K | M | N | A | A | F | P | E | L | N | W | Q | I | P | Q | S | T | Y | L | A | W | L | D | L | R | P | L | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T | S |
|
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|
|
|
|
|
| S | B |
| S |  |  |  |  |  |
| G | G | G |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . |
  |
  |   |
349 | 350 | . | . | . | . | . | . | . | . | . | 360 | . | |
. | . | . | . | . | . | . | |
|
|
|
|
|
. | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
| . |
|  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Q | A | K | Q | I | S | Q | E | A | A | K | A | . |
G | V | M | V | L | I | A | . |
. |
. |
. |
. |
. |
G | G | N | V | V | R | F | A | P | A | L | N | V | S | E | E | E | V | T | T | G | L | D | R | F | A | A | A | C | E | H | F |
Query Conservation |   |
  |   |
|   |   |
|   |   |   |
|   |
|   | . |
|
|   |   |   |
|   | . | . | . | . | . | . |
|   |   |   |
|
|
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |
|
|
| . | . |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |
Template Sequence |   |
I | D | D | N | A | L | Q | K | A | L | I | E | Q | E | K | V | A | I | M | P | G | Y | T | Y | G | E | E | G | R | G | F | V | R | L | . |
. |
N | A | G | C | P | R | S | K | L | E | K | G | V | A | G | L | I | N | A | I | R | A | V |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|  |  | G | G | G | G |
| G | G | G | T | T |  |  |  |  | . | . |  |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|  |  |  |  | . | . |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
333 | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | |
|
. | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . |
  |