|   |
42 | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | |
|
. | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | D | F | A | G | G | I | A | V | N | A | L | G | H | A | H | P | E | L | R | E | A | L | N | E | Q | A | S | K | F | W | H | T | G | N | G | Y | T | N | E | P | V | L | R | L | A | K | K | L | I | D | A | T | F | . |
. |
A | D | R | V | F | F | C | N | S | G | A | E | A | N | E | A | A | L | K | L | A | R | K | F |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   | . | . |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |
|
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
|   |
|   |   |
| . | . |   |   |   |   |   | . |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |
|   |   |   |   |
|   |
|
|   |
|   |   |   |
|
|   |   |   |   |   |   | . | . | . | . |
Template Sequence |   |
V | C | L | A | F | N | . |
. |
E | N | P | E | A | . |
V | E | P | R | V | Q | A | A | I | A | A | A | A | A | R | . |
. |
. |
. |
I | N | R | Y | P | F | D | A | E | P | R | V | X | R | K | L | A | E | H | F | S | C | P | E | D | N | L | X | L | V | R | G | I | D | E | C | F | D | R | I | S | A | E | . |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  | S | S |
| . | . |
|
|
| S |
| . |
|
|  |  |  |  |  |  |  |  |  |  | G | G | G | . | . | . | . | T | T | S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| G | G | G |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |
|
|
|
| . | . |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
18 | . | 20 | . | . | . | |
|
. | . | . | . | . | |
. | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | |
|
|
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | |
|
|
|
  |
  |   |
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | H | D | R | Y | G | S | H | K | S | G | I | V | A | F | K | N | A | F | H | G | R | T | L | F | T | V | S | A | G | G | Q | P | A | Y | S | Q | D | F | A | P | L | P | A | D | I | R | H | A | A | Y | N | D | I | N | S | A | S | A | L | I | D | D | S | T | C | A | V | I | V | E | P | I | Q | G | E | G | G | V | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . |   |   |
|
|   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
F | S | S | X | R | F | V | T | A | W | P | G | F | D | G | Y | R | A | R | I | A | V | S | G | L | R | H | F | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | G | L | T | D | D | L | L | L | D | P | N | D | L | A | Q | V | S | R | D | D | C | V | V | L | A | N | P | S | N | P | T | G | Q | A |
Template Known Secondary structure |   |
. | . | . | . | . | . | S | T | T | S |  |  |  |  |  | S | S | S |
| S |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |
| B |
| T | T | S | S | B |
|  |  |  |  | T | T |
|
| T | T |  |  |  |  |  |  | S | S |
| T | T | T |
|
|
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
87 | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 |
  |
  |   |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | |
. | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|  |  |
| . |
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | A | S | N | A | F | L | Q | G | L | R | E | L | C | N | R | H | N | A | L | L | I | F | D | E | V | Q | T | G | V | G | R | T | G | E | L | Y | A | Y | M | H | Y | G | V | T | P | D | L | L | T | T | A | K | A | L | G | . |
G | G | F | P | V | G | A | L | L | A | T | E | E | C | A | R | V | M | T | V | G | T | H |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |   |   | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
L | . |
. |
. |
. |
. |
S | A | G | E | L | D | Q | L | R | Q | R | A | G | K | L | L | I | D | E | T | Y | V | D | Y | S | S | F | R | A | R | G | L | A | Y | . |
G | E | N | E | L | V | F | R | S | F | S | K | S | Y | G | L | A | G | L | R | L | G | A | L | F | G | P | S | E | L | I | A | A | X | K | R | K | Q | W |
Template Known Secondary structure |   |
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |  |
| T | T | G | G | G | S | S |
| S | T | T |
|
|
|
| . | B | T | T |  |  |  |  |  |  | S | S | S | T | T | S |
| T | T | T |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  | T | T | S |
|
Template Predicted Secondary structure |   |
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |
|  |  |  |  |
|
|  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
151 | |
|
|
|
|
. | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | |
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . |
  |
  |   |
279 | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | T | T | Y | G | G | N | P | L | A | S | A | V | A | G | K | V | L | E | L | I | N | T | P | E | M | L | N | G | V | K | Q | R | H | D | W | F | V | E | R | L | N | T | I | N | H | R | Y | G | L | F | S | E | V | R | G | L | G | L | L | I | G | C | V | L | N | A | D | Y | A | G | Q | A | K | Q | I | S | Q | E | A |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |
|
Template Sequence |   |
F | C | N | V | G | T | L | D | L | H | A | L | E | A | A | . |
. |
. |
. |
. |
L | D | N | D | R | A | R | E | A | H | I | A | K | T | L | A | Q | R | R | R | V | A | D | A | L | R | G | L | G | Y | R | V | . |
A | S | S | E | A | N | F | V | L | V | E | N | A | A | G | . |
. |
. |
. |
. |
E | R | T | L | R | F | L |
Template Known Secondary structure |   |
T | T | S | S |
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| B | . |
|
|
| S | S | S |  |  |  |  |  |
| T | T | T | . | . | . | . | . |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  | . | . | . | . | . |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
. | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 290 | . | . | . |
  |
  |   |
359 | 360 | . | . | . | . | . | . | . | . | . | |
|
|
|
370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | K | A | G | V | M | V | L | I | A | G | . |
. |
. |
. |
G | N | V | V | R | F | A | P | A | L | N | V | S | E | E | E | V | T | T | G | L | D | R | F | A | A | A | C | E |
Query Conservation |   |
  |
|   |
|
|   |   |   |
|   |
| . | . | . | . |   |   |   |
|
|
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |
|   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |
|
|
|
|   |   | . | . | . |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |
|
Template Sequence |   |
R | E | R | G | I | Q | V | K | D | A | G | Q | F | G | L | H | H | H | I | R | I | S | I | G | . |
. |
. |
R | E | E | D | N | D | R | L | L | A | A | L | A | E | Y | S | D |
Template Known Secondary structure |   |
 |  | T | T |  |  |  |  |  | G | G | G | G | T |
|
| S |  |  |  |  |  |
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
294 | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | |
|
|
. | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
  |