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Job DescriptionP77581
Confidence99.95%DateThu Jan 5 12:30:46 GMT 2012
Rank122Aligned Residues341
% Identity14%Templatec3e9kA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex
Resolution1.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   36...40.........50.........60.........70 .........80.........90...... ...100......
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Query Sequence  QQGKEYIDFAGGIAVNALGHAHPELREALNEQASK. . . . . . . FWHTGNGYTNEPVLRLAKKLIDATFA. . DRVFFCNSGA
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Template Sequence  DENAIYFLGNS. . . . . . LGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALT
Template Known Secondary structure  T
B

BTTT......S

B
TTGGGGGTSSSS
GGGTTGGGT

GGG
S
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   65....70..... ....80.........90.........100.........110.........120.........130........
 
   107..110.........120.........130.........140.........150...... ...160.........170.........180..
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Query Sequence  EANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQ. . . . DFAPLPADIRHAAYNDINSASALIDD
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Template Sequence  VNLHLLMLSFFKP. . . . . TPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGD
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SSS
TT

TT




TT
SS

GG
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   139140.........150. ........160.........170.........180.........190.........200.........210...
 
   183......190.........200.........210.........220.........230.........240.........250....... ..260.
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Query Sequence  STCAVIVEPIQGEGGVVPASNAFLQGLRELCNRHNALLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGG. FPVG
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Template Sequence  SIAVILFSGVHFYTGQHFN. . . . IPAITKAGQAKGCYVGFDLAHA. . . VGNVELYLHDWGVDFACWCSYKYLNAGAGGIA
Template Known Secondary structure  GSB
TTT
BB

....TT

TTT...TTTS


T


SSSTT


TT


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   214.....220.........230.. .......240.........250.... .....260.........270.........280......
 
   262.......270.........280. ........290.........300.........310.......
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Query Sequence  ALLATEECARVMTVGTHGTT. . . . . . . . . . . . . . . . . . . . . . . . YGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVE
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Template Sequence  GAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTG
Template Known Secondary structure 
GGGTTTS

SS

GGGB
TT

S


B
SSGGGG

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   287..290.........300.........310.........320.........330.........340.........350.........360......
 
   318.320.........330.... .....340.........350.........360.........370....... ..380.........390
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Query Sequence  RLNTINHRYGLFSEVRG. . . . . . LGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAP. ALNVSEEEVTTGL
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Template Sequence  YLEYLIKHNYGVVNIITPSHVEERGCQLTITFSVPNKD. . . . VFQELEKRGVVCDKRNPNGIRVAPVPLYNSFHDVYKFT
Template Known Secondary structure 



S
SSGGGB
S


TT

....TTT
TTTB

TTT

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   367..370.........380.........390.........400.... .....410.........420.........430.........440..
 
   391.......
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Query Sequence  DRFAAACE
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Template Sequence  NLLTSILD
Template Known Secondary structure  T
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   452.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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