|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | A | A | I | A | F | I | G | L | G | Q | M | G | S | P | M | A | S | N | L | L | Q | Q | G | H | Q | L | R | V | F | D | V | N | A | E | A | V | R | H | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | D | K | G | A | T | P | A | A | N | P | A | Q | A | A | K | D | A | E | F | I | I |
Query Conservation |   |
|   |   |
|   |
|
|
|   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |
|   |
Alig confidence |   |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
| . |
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |   |
|
| . |   |
|   |   |
|   |
|   |
|   |   |   |   |   |
|
|   |
|   |   |
|   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
Template Sequence |   |
M | K | . |
I | A | V | A | G | S | G | Y | V | G | L | S | L | G | V | L | L | S | . |
L | Q | N | E | V | T | I | V | D | I | L | P | S | K | V | D | K | I | N | N | G | L | S | P | I | Q | D | E | Y | I | E | Y | Y | L | K | S | K | Q | L | S | I | K | A | T | L | D | S | K | A | A | Y | K | E | A | E | L | V | I |
Template Known Secondary structure |   |
|  | . |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  | T | . | T | T | S |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  | T | T |
|
| S | S |
|
|  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  | S |
|  |  |  |  |  |  |  |
| S |  |  |  |
Template Predicted Secondary structure |   |
|  | . |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | |
. | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
. | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
  |
  |   |
63 | . | . | . | . | . | . | 70 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | M | L | P | N | G | D | L | V | R | . |
. |
. |
. |
. |
. |
N | V | L | F | G | E | N | G | V | C | E | G | L | S | T | D | A | L | V | I | D | M | S | T | I | H | P | L | Q | T | D | K | L | I | A | D | M | Q | A | K | G | F | S | M | M | D | V | P | V | G | R | T | S | A | N | A | I | T | G | T | L | L | L | L |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |   |
|
|
|   |
|
|
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |
|   |   |   |   |   |   |
|   |
|
|
Template Sequence |   |
I | A | T | P | T | N | Y | N | S | R | I | N | Y | F | D | T | Q | H | V | E | T | V | I | K | E | V | L | S | V | N | S | H | A | T | L | I | I | K | S | T | I | P | I | G | F | I | T | E | M | R | Q | K | F | Q | T | D | R | I | I | F | S | P | E | F | L | R | E | S | K | A | L | Y | D | N | L | Y | P | S | R | I |
Template Known Secondary structure |   |
 |
|
|
|
|
|  |  | T | T | T | T |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |
| S |
|
|
| T | T |  |  |  |  |  |  |  |  |  | T |
| S |
|  |  |  |
|
|
|
|
|
| T | T | S | T | T |  |  |  |  | S |
| S |
|  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
137 | . | . | 140 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | |
|
|
. | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | G | T | A | E | . |
. |
. |
. |
. |
. |
. |
. |
Q | V | E | R | A | T | P | I | L | M | A | M | G | S | E | L | . |
. |
. |
I | N | A | G | G | P | G | M | G | I | R | V | K | L | I | N | N | Y | M | S | I | A | L | N | A | L | S | A | E | A | A | V | L | C | E | A | L | N | L | P | F | D | V | A | V | K | V |
Query Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |
|   |
|   |   |
|
|
|   |   |   |
|   |   |
|
Template Sequence |   |
I | V | S | C | E | E | N | D | S | P | K | V | K | A | D | A | E | K | F | A | L | L | L | K | S | A | A | K | K | N | N | V | P | V | L | I | M | G | A | S | E | A | E | A | V | K | L | F | A | N | T | Y | L | A | L | R | V | A | Y | F | N | E | L | D | T | Y | A | E | S | R | K | L | N | S | H | M | I | I | Q | G |
Template Known Secondary structure |   |
 |  |  |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
  |
  |   |
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | S | G | T | A | A | G | K | G | H | F | T | T | S | W | P | N | K | V | L | S | G | D | L | S | P | A | F | M | I | D | L | A | H | K | D | L | G | I | A | L | D | V | A | N | Q | L | H | V | P | M | P | L | G | A | A | S | R | E | V | Y | S | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |
|   |
|
|   |
|
|
|   |
|   |   |   |
| . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
I | S | Y | D | D | R | I | G | M | H | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | N | P | S | F | G | Y | G | G | Y | C | L | P | K | D | T | K | Q | L | . |
. |
L | A | N | Y | N | N | I | P | Q | T | L | I | E | A | I | V | S | S | N | N | V |
Template Known Secondary structure |   |
 |  | T | S | T | T | T |
| S | S | S | . | . | . | . | . | . | . | . | . | . |
|
|
|
| S |
|
|
| S | S |  |  |  |  |  |  |  |  |  | . | . |  |  |  | T | T | T | S | S |
| S |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | |
|
. | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
  |