|   |
189 | 190 | . | . | |
. | . | . | . | . | . | |
|
|
|
|
|
. | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . |
Predicted Secondary structure |   |
|  |  |  | . |  |
|
|
|  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
| . |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | L | S | D | . |
V | I | G | Q | E | Q | . |
. |
. |
. |
. |
. |
G | K | R | G | L | E | I | T | A | A | G | G | H | N | L | L | L | I | G | P | P | G | T | G | K | T | M | L | A | S | R | I | N | G | L | L | P | D | L | S | N | E | E | A | L | E | S | A | A | I | L | S | L | V | N | A | E | S | V | Q | K | Q | W |
Query Conservation |   |
|   |   |
| . |
|   |
|
|   |   | . | . | . | . | . | . |
|
|
|
|
|   |
|
|
|
|
|   |
|   |
|
|
|   |
|   |
|
|
|
|
|
|   |
|
|
|   |
|   |   |
|
|
|   |
|   |   |   |
|   |   |
|   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | L | E | N | F | I | V | G | E | G | N | R | L | A | Y | E | V | V | K | E | A | L | E | N | L | G | S | L | Y | N | P | I | F | I | Y | G | S | V | G | T | G | K | T | H | L | L | Q | A | A | G | N | E | A | . |
. |
. |
. |
. |
. |
K | K | R | G | Y | R | V | I | Y | S | S | A | D | D | F | A | Q | A | X | V | E |
Template Known Secondary structure |   |
| S | S | S |
|
|
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | S |
| S | S |  |  |  |  |
| S | S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . |
  |
  |   |
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | |
|
. | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | Q | R | P | F | R | S | P | H | H | S | A | S | L | T | A | M | V | G | G | G | A | I | P | G | P | G | E | I | S | L | A | H | N | G | V | L | F | L | D | E | L | P | E | F | . |
. |
E | R | R | T | L | D | A | L | R | E | P | I | E | S | G | Q | I | H | L | S | R | T | R | A | K | I | T | Y | P | A | R | F | Q |
Query Conservation |   |
  |   |   |
|
|
|   |
|
|   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |
|
|   |
|   |
|
|
|   |
|
|
|
|
|
|
|
|   |   |   | . | . |   |   |   |
|
|   |   |
|
|   |   |
|
|
|
|   |
|   |
|   |
|   |
|   |   |   |   |   |
|
|   |
|   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Template Sequence |   |
H | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | K | G | T | I | N | E | F | R | N | X | Y | K | S | V | D | L | L | L | L | D | D | V | Q | F | L | S | G | K | E | R | T | Q | I | E | F | F | H | I | F | N | T | L | Y | L | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | K | Q |
Template Known Secondary structure |   |
 |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  | T |
|  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  |
| G | G | G | G | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | . | . | T |
|  |
Template Predicted Secondary structure |   |
 |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
158 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
  |
  |   |
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | A | A | M | N | P | S | P | T | G | H | Y | Q | G | N | H | N | R | C | T | P | E | Q | T | L | R | Y | L | N | R | L | S | G | P | F | L | D | R | F | D | L | S | L | E | I | P | L | P | P | P | G | I | L | S | K | T | V | V | P | G | E | S | S | A | T | V | K | Q | R | V | M | A | A | R | E | R | Q | F | K |
Query Conservation |   |
|
|
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |
Template Sequence |   |
I | I | L | A | S | D | R | H | P | Q | K | L | D | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | S | D | R | L | V | S | R | F | E | G | G | I | L | V | E | I | E | L | D | N | K | T | R | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | I | I | K | E |
Template Known Secondary structure |   |
 |  |  |  |  | S | S |
| G | G | G |
| T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |
|  |  |  |  |  |  |  |  | T | S |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
209 | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 250 | . | . |
  |
  |   |
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | |
|
|
. | . | . | . | . | . | . | . | 450 | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | Q | N | K | L | N | A | W | L | D | S | P | E | I | R | Q | F | C | K | L | E | S | . |
. |
. |
E | D | A | M | W | L | E | G | T | L | I | H |
Query Conservation |   |
|   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |
|   |
|   |   | . | . | . |   |
|   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |
|   |   |   |
Template Sequence |   |
K | L | K | E | F | N | L | E | L | R | K | E | V | I | D | Y | L | L | E | N | T | K | N | V | R | E | I | E | G | K | I | K | L | I | K | L | K |
Template Known Secondary structure |   |
 |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
  |