|   |
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | E | E | F | Y | G | M | E | D | A | I | E | Q | I | V | S | Y | L | K | H | A | A | Q | G | L | E | E | K | K | Q | I | L | Y | L | L | G | P | V | G | G | G | K | S | S | L | A | E | R | L | K | S | L | M | Q | L | V | P | I | Y | V | L | S | A | N | G | E | R | S | P | V | N | D | H | P | F | C | L | F | N | P |
Query Conservation |   |
  |
|   |
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|   |
|
|
|
|
|   |
|
|   |
|
|   |   |
|
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   | . | . | . | . | . | . |   |   |   |   |   |
|
|
|   |
|
|   |
|   |
|
|
|
|
|
|   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
L | D | D | I | V | G | Q | E | H | I | V | K | R | L | K | H | Y | V | K | T | . |
. |
. |
. |
. |
. |
G | S | M | P | H | L | L | F | A | G | P | P | G | V | G | K | T | T | A | A | L | A | L | A | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T | T | T |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | T |
|
|
|  |  |  |  |  | S |
| T | T | S | S |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
24 | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | E | D | A | Q | I | L | E | K | E | Y | G | I | P | R | R | Y | L | G | T | I | M | S | P | W | A | A | K | R | L | H | E | F | G | G | D | I | T | K | F | R | V | V | K | V | W | P | S | I | L | Q | Q | I | A | I | A | K | T | E | P | G | D | E | N | N | Q | D | I | S | A | L | V | G | K | V | D | I | R | K | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|
|   |   |
|   |
|
|   |
|   |   |
|
|
|
|   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | L | F | G | E | N | W | R | H | N | F | L | E | L | N | A | S | D | E | R | G | I | N | V | I | R | E | K | . |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  | T | T |  |  |  | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
69 | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | |
|
|
|
  |
  |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | H | Y | A | Q | N | D | P | D | A | Y | G | Y | S | G | A | L | C | R | A | N | Q | G | I | M | E | F | V | E | M | F | K | A | P | I | K | V | L | H | P | L | L | T | A | T | Q | E | G | N | Y | N | G | T | E | G | I | S | A | L | P | F | N | G | I | I | L | A | H | S | N | E | S | E | W | V | T | F | R | N | N |
Query Conservation |   |
  |   |
|   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
Template Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
V | K | E | F | A | R | T | K | P | I | G | G | A | S | F | K | I | I | F | L | D | E | A | D | A | L | T | Q | D | A | Q | Q | A | L | R | R | T | M | E | M | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | S | N | V | R | F | I | L | S | C | N | Y | S | . |
. |
. |
. |
. |
. |
. |
S |
Template Known Secondary structure |   |
. | . | . | . | . | . | . |  |  |  |  |  |  | S |
|
| G | G | G |
| S |
|  |  |  |  |  |  | T | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | . | T | T | T |  |  |  |  |  |  |  | S |
| G | . | . | . | . | . | . | . | G |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
97 | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | 140 | . | . | . | . | . | . | . | . | . | 150 | |
|
|
|
|
|
|
. |
  |
  |   |
315 | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | N | N | E | A | F | L | D | R | V | Y | I | V | K | V | P | Y | C | L | R | I | S | E | E | I | K | I | Y | E | K | L | L | N | H | S | E | L | T | H | A | P | C | A | P | G | T | L | E | T | L | S | R | F | S |
Query Conservation |   |
  |   |   |
|   |
|   |
|
|
|   |   |
|   |
|
|
|   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   | . | . | . |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|
Template Sequence |   |
K | I | I | E | P | I | Q | S | R | C | A | I | F | R | F | R | P | L | . |
R | D | E | D | I | A | K | R | L | R | Y | I | A | E | N | E | . |
. |
. |
G | L | E | L | T | E | E | G | L | Q | A | I | L | Y | I | A |
Template Known Secondary structure |   |
G | S |
|  |  |  |  |  | T |  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | T |
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
152 | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | |
|
|
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . |
  |