Job Description P76558 Confidence 100.00% Date Thu Jan 5 12:24:36 GMT 2012 Rank 5 Aligned Residues 371 % Identity 28% Template c1gz3B_ PDB info PDB header:oxidoreductase Chain: B: PDB Molecule:nad-dependent malic enzyme; PDBTitle: molecular mechanism for the regulation of human mitochondrial2 nad(p)+-dependent malic enzyme by atp and fumarate Resolution 2.3 Å

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		33	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.				.	50	.	.	.	.	.	.	.	.		.	60	.	.	.	.	.														.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.
Predicted Secondary structure																		.	.	.											.								.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																		.	.	.											.								.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		R	D	L	A	L	A	Y	S	P	G	V	A	A	P	C	L	.	.	.	E	I	E	K	D	P	L	K	A	Y	.	K	Y	T	A	R	G	N	.	.	.	.	.	.	.	.	.	.	.	.	.	L	V	A	V	I	S	N	G	T	A	V	L	G	L	G	N	I	G	A	L	A	G	K	P	V	M	E	G	K	G
Query Conservation																		.	.	.											.								.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																		.	.	.											.								.	.	.	.	.	.	.	.	.	.	.	.	.																				.
Template Conservation																																																																							.
Template Sequence		S	L	M	P	I	V	Y	T	P	T	V	G	L	A	C	S	Q	Y	G	H	I	F	R	R	P	K	G	L	F	I	S	I	S	D	R	G	H	V	R	S	I	V	D	N	W	P	E	N	H	V	K	A	V	V	V	T	D	G	E	R	I	L	G	L	G	D	L	G	V	.	Y	G	M	G	I	P	V	G	K	L
Template Known Secondary structure								S	T	T								T						S	S			S					G	G	G	T	T							T	T		S		S										S	S	S	B	T	T	T	B			G	G	.	G	G	G
Template Predicted Secondary structure																																																																							.
Template SS confidence
		106	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.		.	.	.	.	.	180	.	.	.	.
		96	.	.	.	100	.	.	.	.	.								.	.	.	.	110	.	.	.	.	.																								.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.
Predicted Secondary structure												.	.	.	.	.	.	.											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence												.	.	.	.	.	.	.											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		V	L	F	K	K	F	A	G	I	D	.	.	.	.	.	.	.	V	F	D	I	E	V	D	E	L	D	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	D	K	F	I	E	V	V	A	A	L	E	P	T	F	G	G	I	N	L	E	D	I	K	A	P	E	C	F	Y
Query Conservation												.	.	.	.	.	.	.											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence												.	.	.	.	.	.	.											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		C	L	Y	T	A	C	A	G	I	R	P	D	Q	C	L	P	V	C	I	D	V	G	T	D	N	I	A	L	L	K	D	P	F	Y	M	G	L	Y	Q	K	R	D	R	T	Q	Q	Y	D	D	L	I	D	E	F	M	K	A	I	T	D	R	Y	G	R	N	T	L	I	Q	F	E	D	F	G	N	H	N	A	F	R
Template Known Secondary structure												G	G	G								S									T		T	T			S		S	S					S																				T	T							S
Template Predicted Secondary structure
Template SS confidence
		185	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.
		146	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.									.	.	.	.
Predicted Secondary structure																																																																						.	.	.	.	.	.	.	.
Query SS confidence																																																																						.	.	.	.	.	.	.	.
Query Sequence		I	E	Q	K	L	R	E	R	M	N	I	P	V	F	H	D	D	Q	H	G	T	A	I	I	S	T	A	A	I	L	N	G	L	R	V	V	E	K	N	I	S	D	V	R	M	V	V	S	G	A	G	A	A	A	I	A	C	M	N	L	L	V	A	L	G	L	Q	K	.	.	.	.	.	.	.	.	H	N	I	V
Query Conservation																																																																						.	.	.	.	.	.	.	.
Alig confidence										.	.																																																											.	.	.	.	.	.	.	.
Template Conservation										.	.
Template Sequence		F	L	R	K	Y	R	E	K	.	.	Y	C	T	F	N	D	D	I	Q	G	T	A	A	V	A	L	A	G	L	L	A	A	Q	K	V	I	S	K	P	I	S	E	H	K	I	L	F	L	G	A	G	E	A	A	L	G	I	A	N	L	I	V	M	S	M	V	E	N	G	L	S	E	Q	E	A	Q	K	K	I	W
Template Known Secondary structure							T	T	T	.	.	S	S				T	T	T	T																					T	T	T									S																	T	T									T
Template Predicted Secondary structure										.	.
Template SS confidence
		265	.	.	.	.	270	.	.			.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.
		218	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.			.	.	.	.	.	250	.	.	.	.	.			.	.	.	.	260	.	.	.	.	.		.	.	.	.	270	.	.	.	.	.	.	.	.				.	280	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																													.	.												.	.											.														.	.	.
Query SS confidence																													.	.												.	.											.														.	.	.
Query Sequence		V	C	D	S	K	G	V	I	Y	Q	G	R	E	P	N	M	A	E	T	K	A	A	Y	A	V	V	D	.	.	D	G	K	R	T	L	D	D	V	I	E	.	.	G	A	D	I	F	L	G	C	S	G	.	P	K	V	L	T	Q	E	M	V	K	K	M	A	.	.	.	R	A	P	M	I	L	A	L	A	N	P
Query Conservation																													.	.												.	.											.														.	.	.
Alig confidence																													.	.												.	.											.														.	.	.
Template Conservation
Template Sequence		M	F	D	K	Y	G	L	L	V	K	G	R	K	A	K	I	D	S	Y	Q	E	P	F	T	H	S	A	P	E	S	I	P	D	T	F	E	D	A	V	N	I	L	K	P	S	T	I	I	G	V	A	G	A	G	R	L	F	T	P	D	V	I	R	A	M	A	S	I	N	E	R	P	V	I	F	A	L	S	N	P
Template Known Secondary structure					T	T				B	T	T		S	S				T	T	T	G	G	G		B				S	S			S	S											S							S	S	S			S													S	S								S	S
Template Predicted Secondary structure
Template SS confidence
		343	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.
		290			.	.	.	.	.	.	.	.	.		300	.	.	.	.	.	.	.	.	.	310												.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.
Predicted Secondary structure			.	.										.												.	.	.	.	.	.	.	.	.	.	.
Query SS confidence			.	.										.												.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	.	.	P	E	I	L	P	P	L	A	K	.	E	V	R	P	D	A	I	I	C	T	G	.	.	.	.	.	.	.	.	.	.	.	R	S	D	Y	P	N	Q	V	N	N	V	L	C	F	P	F	I	F	R	G	A	L	D	V	G	A	T	A	I	N	E	E	M	K	L	A	A	V	R	A	I	A	E	L	A
Query Conservation			.	.										.												.	.	.	.	.	.	.	.	.	.	.
Alig confidence			.	.										.												.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		T	A	Q	A	E	C	T	A	E	E	A	Y	T	L	T	E	G	R	C	L	F	A	S	G	S	P	F	G	P	V	K	L	T	D	G	R	V	F	T	P	G	Q	G	N	N	V	Y	I	F	P	G	V	A	L	A	V	I	L	C	N	T	R	H	I	S	D	S	V	F	L	E	A	A	K	A	L	T	S	Q	L
Template Known Secondary structure		G	G	G	S	S	S									T	T	T							S	S								T	T	S										G	G	G	T											T	T		S																T	T
Template Predicted Secondary structure
Template SS confidence
		423	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.
		356	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.		.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410			.	.	.	.	.	.	.	.	.	420
Predicted Secondary structure																																		.																								.	.
Query SS confidence																																		.																								.	.
Query Sequence		H	A	E	Q	S	E	V	V	A	S	A	Y	G	D	Q	D	L	S	F	G	P	E	Y	I	I	P	K	P	F	D	P	R	.	L	I	V	K	I	A	P	A	V	A	K	A	A	M	E	S	G	V	A	T	R	P	I	.	.	A	D	F	D	V	Y	I	D	K	L
Query Conservation																																		.																								.	.
Alig confidence					.	.	.	.	.	.	.	.	.	.	.	.	.	.																.																								.	.
Template Conservation					.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		T	D	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	L	A	Q	G	R	L	Y	P	P	L	A	N	I	Q	E	V	S	I	N	I	A	I	K	V	T	E	Y	L	Y	A	N	K	M	A	F	V	Y	P	E	P	E	D	K	A	K	Y	V	K	E	Q
Template Known Secondary structure					.	.	.	.	.	.	.	.	.	.	.	.	.	.				T	T		S	S			G	G	G																			T	T					S	S			S
Template Predicted Secondary structure					.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		503	.	.															.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.