|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
M | S | T | L | L | Y | L | H | G | F | N | S | S | P | R | S | A | K | A | S | L | L | K | N | W | L | A | E | H | H | . |
. |
. |
. |
. |
P | D | V | E | M | I | I | P | Q | L | P | P | Y | P | S | D | A | A | E | L | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|   |
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
| . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Y | P | V | I | Y | V | L | D | G | N | A | F | F | Q | T | F | H | E | A | V | K | I | Q | S | V | R | A | E | K | T | G | V | S | P | A | I | I | V | G | V | G | Y | P | I | E | G | A | F | S | G | E | E | R | C | Y | D | F | T | P | S | V | I | S | K | D | A | P | L | K | P | D | G | K | P | W | P | K | T | G | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
| S |
| S | S | S |
|
| S |  |  |  |  |  |  |  |
| S | S |
|
|
| T | T |
|
|
|
| T | T |
|
|
|
|
|
|
|
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
45 | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
52 | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | S | I | V | L | E | H | G | G | D | S | L | G | I | V | G | S | S | L | G | G | Y | Y | A | T | W | L | S | Q | C | F | M | L | P | A | V | V | V | N | P | A | V | R | P | F | E | L | L | T | D | Y | L | G | Q | N | E | N | P | Y | T | G | Q | Q | Y | V | L |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
Template Sequence |   |
A | H | N | F | F | T | F | I | E | E | E | L | K | P | Q | I | E | K | N | F | E | I | D | K | G | K | Q | T | L | F | G | H | L | G | G | L | F | A | L | H | I | L | F | T | N | L | N | A | F | Q | N | Y | F | I | S | S | P | S | I | W | W | N | N | K | S | V | L | E | K | E | E | N | L | . |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |
| S |  |  |  |  |  | S |
|
| T | T |  |  |  |  | G | G | G | G | G | T | T |  |  | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
125 | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
  |
  |   |
118 | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | S | R | H | I | Y | D | L | K | V | M | Q | I | D | P | L | E | A | P | D | L | I | W | L | L | Q | Q | T | G | D | E | V | L | D | Y | R | Q | A | V | A | Y | Y | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | C | R | Q | T | V | I | E | G | G | N | H | A | F | T | G | F | E | D | Y | F | N | P | I | V | D | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |
| . |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | I | E | L | N | N | A | K | F | E | T | G | V | F | L | T | V | G | S | L | E | R | E | H | X | V | V | G | A | N | E | L | S | E | R | L | L | Q | V | N | H | D | K | L | K | F | K | F | Y | E | A | E | G | E | N | H | . |
A | S | V | V | P | T | S | L | S | K | G | L | R | F |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  | T | T |
|
| T | . | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
199 | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | |
. | . | . | . | . | 260 | . | . | . | . | . | . | . | . |
  |
  |   |
188 | . |
Predicted Secondary structure |   |
 |  |
Query SS confidence |   |
|
|
Query Sequence |   |
L | G |
Query Conservation |   |
|   |
Alig confidence |   |
|
|
Template Conservation |   |
  |   |
Template Sequence |   |
I | S |
Template Known Secondary structure |   |
 |
|
Template Predicted Secondary structure |   |
 |  |
Template SS confidence |   |
|
|
  |   |
269 | 270 |
  |