Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	Y	N	I	P	C	R	I	Y	I	L	S	T	L	S	L	C	I	S	G	I	V	S	T	A	T	A	T	S	S	E	T	K	I	S	N	E	E	T	L	V	V	T	T	N	R	S	A	S	N	L	W	E	S	P	A	T	I	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?												?	?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	I	D	Q	Q	T	L	Q	N	S	T	N	A	S	I	A	D	N	L	Q	D	I	P	G	V	E	I	T	D	N	S	L	A	G	R	K	Q	I	R	I	R	G	E	A	S	S	R	V	L	I	L	I	D	G	Q	E	V	T	Y	Q
Secondary structure
SS confidence
Disorder											?	?	?	?											?					?	?	?	?	?	?	?	?																					?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.
Sequence		R	A	G	D	N	Y	G	V	G	L	L	I	D	E	S	A	L	E	R	V	E	V	V	K	G	P	Y	S	V	L	Y	G	S	Q	A	I	G	G	I	V	N	F	I	T	K	K	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?		?	?																																			?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3fhh chain A Region: 39 - 167 Aligned: 126 Modelled: 129 Confidence: 100.0% Identity: 33% PDB header:membrane protein Chain: A: PDB Molecule:outer membrane heme receptor shua; PDBTitle: crystal structure of the heme/hemoglobin outer membrane2 transporter shua from shigella dysenteriae Phyre2 PDB 2hdi chain A Region: 39 - 167 Aligned: 128 Modelled: 129 Confidence: 100.0% Identity: 45% PDB header:protein transport,antimicrobial protein Chain: A: PDB Molecule:colicin i receptor; PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia. Phyre2 PDB 3qlb chain A Region: 29 - 167 Aligned: 132 Modelled: 139 Confidence: 100.0% Identity: 27% PDB header:metal transport Chain: A: PDB Molecule:enantio-pyochelin receptor; PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin Phyre2 PDB 3efm chain A Region: 26 - 167 Aligned: 137 Modelled: 142 Confidence: 100.0% Identity: 18% PDB header:membrane protein Chain: A: PDB Molecule:ferric alcaligin siderophore receptor; PDBTitle: structure of the alcaligin outer membrane recepteur faua from2 bordetella pertussis Phyre2 PDB 1xkw chain A Region: 32 - 167 Aligned: 128 Modelled: 136 Confidence: 100.0% Identity: 23% PDB header:membrane protein Chain: A: PDB Molecule:fe(iii)-pyochelin receptor; PDBTitle: pyochelin outer membrane receptor fpta from pseudomonas2 aeruginosa Phyre2 PDB 1by5 chain A Region: 27 - 167 Aligned: 136 Modelled: 141 Confidence: 100.0% Identity: 25% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Ligand-gated protein channel Phyre2 PDB 2guf chain A domain 1 Region: 39 - 167 Aligned: 123 Modelled: 129 Confidence: 100.0% Identity: 38% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Ligand-gated protein channel Phyre2 PDB 1kmo chain A Region: 40 - 167 Aligned: 128 Modelled: 128 Confidence: 100.0% Identity: 27% Fold: Transmembrane beta-barrels Superfamily: Porins Family: Ligand-gated protein channel Phyre2 PDB 1xkh chain C Region: 21 - 167 Aligned: 143 Modelled: 139 Confidence: 100.0% Identity: 27% PDB header:membrane protein Chain: C: PDB Molecule:ferripyoverdine receptor; PDBTitle: pyoverdine outer membrane receptor fpva from pseudomonas aeruginosa2 pao1 bound to pyoverdine Phyre2 PDB 2grx chain B Region: 28 - 167 Aligned: 135 Modelled: 140 Confidence: 100.0% Identity: 25% PDB header:metal transport Chain: B: PDB Molecule:ferrichrome-iron receptor; PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome Phyre2 PDB 2iah chain A Region: 26 - 167 Aligned: 138 Modelled: 142 Confidence: 100.0% Identity: 27% PDB header:membrane protein Chain: A: PDB Molecule:ferripyoverdine receptor; PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine. Phyre2 PDB 1po3 chain A Region: 50 - 167 Aligned: 118 Modelled: 118 Confidence: 100.0% Identity: 28% PDB header:membrane protein Chain: A: PDB Molecule:iron(iii) dicitrate transport protein feca PDBTitle: crystal structure of ferric citrate transporter feca in2 complex with ferric citrate Phyre2 PDB 3csl chain B Region: 49 - 167 Aligned: 119 Modelled: 119 Confidence: 100.0% Identity: 24% PDB header:membrane protein/heme binding protein Chain: B: PDB Molecule:hasr protein; PDBTitle: structure of the serratia marcescens hemophore receptor hasr in2 complex with its hemophore hasa and heme Phyre2 1 c3fhhA_ 2 c2hdiA_ 3 c3qlbA_ 4 c3efmA_ 5 c1xkwA_ 6 d1by5a_ 7 d2gufa1 8 d1kmoa_ 9 c1xkhC_ 10 c2grxB_ 11 c2iahA_ 12 c1po3A_ 13 c3cslB_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3fhhA_ 100.0 33 PDB header:membrane protein Chain: A: PDB Molecule:outer membrane heme receptor shua; PDBTitle: crystal structure of the heme/hemoglobin outer membrane2 transporter shua from shigella dysenteriae 2 c2hdiA_ 100.0 45 PDB header:protein transport,antimicrobial protein Chain: A: PDB Molecule:colicin i receptor; PDBTitle: crystal structure of the colicin i receptor cir from e.coli in complex2 with receptor binding domain of colicin ia. 3 c3qlbA_ 100.0 27 PDB header:metal transport Chain: A: PDB Molecule:enantio-pyochelin receptor; PDBTitle: enantiopyochelin outer membrane tonb-dependent transporter from2 pseudomonas fluorescens bound to the ferri-enantiopyochelin 4 c3efmA_ 100.0 18 PDB header:membrane protein Chain: A: PDB Molecule:ferric alcaligin siderophore receptor; PDBTitle: structure of the alcaligin outer membrane recepteur faua from2 bordetella pertussis 5 c1xkwA_ 100.0 23 PDB header:membrane protein Chain: A: PDB Molecule:fe(iii)-pyochelin receptor; PDBTitle: pyochelin outer membrane receptor fpta from pseudomonas2 aeruginosa 6 d1by5a_ 100.0 25 Fold:Transmembrane beta-barrels Superfamily:Porins Family:Ligand-gated protein channel 7 d2gufa1 100.0 38 Fold:Transmembrane beta-barrels Superfamily:Porins Family:Ligand-gated protein channel 8 d1kmoa_ 100.0 27 Fold:Transmembrane beta-barrels Superfamily:Porins Family:Ligand-gated protein channel 9 c1xkhC_ 100.0 27 PDB header:membrane protein Chain: C: PDB Molecule:ferripyoverdine receptor; PDBTitle: pyoverdine outer membrane receptor fpva from pseudomonas aeruginosa2 pao1 bound to pyoverdine 10 c2grxB_ 100.0 25 PDB header:metal transport Chain: B: PDB Molecule:ferrichrome-iron receptor; PDBTitle: crystal structure of tonb in complex with fhua, e. coli2 outer membrane receptor for ferrichrome 11 c2iahA_ 100.0 27 PDB header:membrane protein Chain: A: PDB Molecule:ferripyoverdine receptor; PDBTitle: crystal structure of the ferripyoverdine receptor of the outer2 membrane of pseudomonas aeruginosa bound to ferripyoverdine. 12 c1po3A_ 100.0 28 PDB header:membrane protein Chain: A: PDB Molecule:iron(iii) dicitrate transport protein feca PDBTitle: crystal structure of ferric citrate transporter feca in2 complex with ferric citrate 13 c3cslB_ 100.0 24 PDB header:membrane protein/heme binding protein Chain: B: PDB Molecule:hasr protein; PDBTitle: structure of the serratia marcescens hemophore receptor hasr in2 complex with its hemophore hasa and heme

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0