Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	N	N	D	T	T	L	Q	L	S	S	V	L	N	R	E	C	T	R	S	R	V	H	C	Q	S	K	K	R	A	L	E	I	I	S	E	L	A	A	K	Q	L	S	L	P	P	Q	V	V	F	E	A	I	L	T	R	E	K	M
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	S	T	G	I	G	N	G	I	A	I	P	H	G	K	L	E	E	D	T	L	R	A	V	G	V	F	V	Q	L	E	T	P	I	A	F	D	A	I	D	N	Q	P	V	D	L	L	F	A	L	L	V	P	A	D	Q	T	K	T	H
Secondary structure
SS confidence
Disorder																																					?		?																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.
Sequence		L	H	T	L	S	L	V	A	K	R	L	A	D	K	T	I	C	R	R	L	R	A	A	Q	S	D	E	E	L	Y	Q	I	I	T	D	T	E	G	T	P	D	E	A
Secondary structure
SS confidence
Disorder																																					?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1a6j chain A Region: 8 - 157 Aligned: 150 Modelled: 150 Confidence: 100.0% Identity: 100% Fold: Phoshotransferase/anion transport protein Superfamily: Phoshotransferase/anion transport protein Family: IIA domain of mannitol-specific and ntr phosphotransferase EII Phyre2 PDB 2a0j chain A Region: 10 - 154 Aligned: 144 Modelled: 145 Confidence: 100.0% Identity: 39% PDB header:transferase Chain: A: PDB Molecule:pts system, nitrogen regulatory iia protein; PDBTitle: crystal structure of nitrogen regulatory protein iia-ntr from2 neisseria meningitidis Phyre2 PDB 3urr chain B Region: 6 - 157 Aligned: 149 Modelled: 152 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: B: PDB Molecule:pts iia-like nitrogen-regulatory protein ptsn; PDBTitle: structure of pts iia-like nitrogen-regulatory protein ptsn (bth_i0484)2 (ptsn) Phyre2 PDB 3oxp chain B Region: 9 - 156 Aligned: 145 Modelled: 147 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:phosphotransferase enzyme ii, a component; PDBTitle: structure of phosphotransferase enzyme ii, a component from yersinia2 pestis co92 at 1.2 a resolution Phyre2 PDB 3oxp chain A Region: 9 - 156 Aligned: 145 Modelled: 147 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:phosphotransferase enzyme ii, a component; PDBTitle: structure of phosphotransferase enzyme ii, a component from yersinia2 pestis co92 at 1.2 a resolution Phyre2 PDB 2oq3 chain A Region: 8 - 155 Aligned: 144 Modelled: 148 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:mannitol-specific cryptic phosphotransferase PDBTitle: solution structure of the mannitol- specific cryptic2 phosphotransferase enzyme iia cmtb from escherichia coli Phyre2 PDB 3bjv chain A Region: 8 - 160 Aligned: 149 Modelled: 151 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:rmpa; PDBTitle: the crystal structure of a putative pts iia(ptxa) from streptococcus2 mutans Phyre2 PDB 2oqt chain D Region: 10 - 160 Aligned: 147 Modelled: 149 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: D: PDB Molecule:hypothetical protein spy0176; PDBTitle: structural genomics, the crystal structure of a putative2 pts iia domain from streptococcus pyogenes m1 gas Phyre2 PDB 1a3a chain A Region: 14 - 155 Aligned: 138 Modelled: 142 Confidence: 100.0% Identity: 25% Fold: Phoshotransferase/anion transport protein Superfamily: Phoshotransferase/anion transport protein Family: IIA domain of mannitol-specific and ntr phosphotransferase EII Phyre2 PDB 1xiz chain A Region: 10 - 158 Aligned: 147 Modelled: 149 Confidence: 100.0% Identity: 18% Fold: Phoshotransferase/anion transport protein Superfamily: Phoshotransferase/anion transport protein Family: IIA domain of mannitol-specific and ntr phosphotransferase EII Phyre2 PDB 1hyn chain Q Region: 9 - 157 Aligned: 148 Modelled: 149 Confidence: 98.2% Identity: 19% PDB header:membrane protein Chain: Q: PDB Molecule:band 3 anion transport protein; PDBTitle: crystal structure of the cytoplasmic domain of human2 erythrocyte band-3 protein Phyre2 PDB 1hyn chain P Region: 9 - 157 Aligned: 148 Modelled: 149 Confidence: 98.2% Identity: 20% Fold: Phoshotransferase/anion transport protein Superfamily: Phoshotransferase/anion transport protein Family: Anion transport protein, cytoplasmic domain Phyre2 PDB 3ntv chain B Region: 17 - 71 Aligned: 55 Modelled: 54 Confidence: 8.9% Identity: 22% PDB header:transferase Chain: B: PDB Molecule:mw1564 protein; PDBTitle: crystal structure of a putative caffeoyl-coa o-methyltransferase from2 staphylococcus aureus Phyre2 PDB 3n6o chain B Region: 135 - 161 Aligned: 27 Modelled: 27 Confidence: 7.9% Identity: 19% PDB header:signaling protein Chain: B: PDB Molecule:guanine nucleotide exchange factor; PDBTitle: crystal structure of the gef and p4m domain of drra/sidm from2 legionella pneumophila Phyre2 PDB 1vco chain A domain 2 Region: 33 - 73 Aligned: 40 Modelled: 41 Confidence: 6.3% Identity: 18% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nitrogenase iron protein-like Phyre2 PDB 3nva chain B Region: 33 - 73 Aligned: 40 Modelled: 41 Confidence: 6.1% Identity: 23% PDB header:ligase Chain: B: PDB Molecule:ctp synthase; PDBTitle: dimeric form of ctp synthase from sulfolobus solfataricus Phyre2 PDB 1vcn chain A Region: 33 - 73 Aligned: 40 Modelled: 41 Confidence: 5.7% Identity: 18% PDB header:ligase Chain: A: PDB Molecule:ctp synthetase; PDBTitle: crystal structure of t.th. hb8 ctp synthetase complex with sulfate2 anion Phyre2 PDB 1nyc chain A Region: 59 - 108 Aligned: 50 Modelled: 50 Confidence: 5.5% Identity: 16% Fold: Streptavidin-like Superfamily: beta-Barrel protease inhibitors Family: Staphostatin Phyre2 PDB 2p9x chain B Region: 113 - 159 Aligned: 47 Modelled: 47 Confidence: 5.2% Identity: 28% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein ph0832; PDBTitle: crystal structure of ph0832 from pyrococcus horikoshii ot3 Phyre2 1 d1a6ja_ 2 c2a0jA_ 3 c3urrB_ 4 c3oxpB_ 5 c3oxpA_ 6 c2oq3A_ 7 c3bjvA_ 8 c2oqtD_ 9 d1a3aa_ 10 d1xiza_ 11 c1hynQ_ 12 d1hynp_ 13 c3ntvB_ 14 c3n6oB_ 15 d1vcoa2 16 c3nvaB_ 17 c1vcnA_ 18 d1nyca_ 19 c2p9xB_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1a6ja_ 100.0 100 Fold:Phoshotransferase/anion transport protein Superfamily:Phoshotransferase/anion transport protein Family:IIA domain of mannitol-specific and ntr phosphotransferase EII 2 c2a0jA_ 100.0 39 PDB header:transferase Chain: A: PDB Molecule:pts system, nitrogen regulatory iia protein; PDBTitle: crystal structure of nitrogen regulatory protein iia-ntr from2 neisseria meningitidis 3 c3urrB_ 100.0 36 PDB header:transferase Chain: B: PDB Molecule:pts iia-like nitrogen-regulatory protein ptsn; PDBTitle: structure of pts iia-like nitrogen-regulatory protein ptsn (bth_i0484)2 (ptsn) 4 c3oxpB_ 100.0 21 PDB header:transferase Chain: B: PDB Molecule:phosphotransferase enzyme ii, a component; PDBTitle: structure of phosphotransferase enzyme ii, a component from yersinia2 pestis co92 at 1.2 a resolution 5 c3oxpA_ 100.0 21 PDB header:transferase Chain: A: PDB Molecule:phosphotransferase enzyme ii, a component; PDBTitle: structure of phosphotransferase enzyme ii, a component from yersinia2 pestis co92 at 1.2 a resolution 6 c2oq3A_ 100.0 19 PDB header:transferase Chain: A: PDB Molecule:mannitol-specific cryptic phosphotransferase PDBTitle: solution structure of the mannitol- specific cryptic2 phosphotransferase enzyme iia cmtb from escherichia coli 7 c3bjvA_ 100.0 18 PDB header:transferase Chain: A: PDB Molecule:rmpa; PDBTitle: the crystal structure of a putative pts iia(ptxa) from streptococcus2 mutans 8 c2oqtD_ 100.0 16 PDB header:transferase Chain: D: PDB Molecule:hypothetical protein spy0176; PDBTitle: structural genomics, the crystal structure of a putative2 pts iia domain from streptococcus pyogenes m1 gas 9 d1a3aa_ 100.0 25 Fold:Phoshotransferase/anion transport protein Superfamily:Phoshotransferase/anion transport protein Family:IIA domain of mannitol-specific and ntr phosphotransferase EII 10 d1xiza_ 100.0 18 Fold:Phoshotransferase/anion transport protein Superfamily:Phoshotransferase/anion transport protein Family:IIA domain of mannitol-specific and ntr phosphotransferase EII 11 c1hynQ_ 98.2 19 PDB header:membrane protein Chain: Q: PDB Molecule:band 3 anion transport protein; PDBTitle: crystal structure of the cytoplasmic domain of human2 erythrocyte band-3 protein 12 d1hynp_ 98.2 20 Fold:Phoshotransferase/anion transport protein Superfamily:Phoshotransferase/anion transport protein Family:Anion transport protein, cytoplasmic domain 13 c3ntvB_ 8.9 22 PDB header:transferase Chain: B: PDB Molecule:mw1564 protein; PDBTitle: crystal structure of a putative caffeoyl-coa o-methyltransferase from2 staphylococcus aureus 14 c3n6oB_ 7.9 19 PDB header:signaling protein Chain: B: PDB Molecule:guanine nucleotide exchange factor; PDBTitle: crystal structure of the gef and p4m domain of drra/sidm from2 legionella pneumophila 15 d1vcoa2 6.3 18 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 16 c3nvaB_ 6.1 23 PDB header:ligase Chain: B: PDB Molecule:ctp synthase; PDBTitle: dimeric form of ctp synthase from sulfolobus solfataricus 17 c1vcnA_ 5.7 18 PDB header:ligase Chain: A: PDB Molecule:ctp synthetase; PDBTitle: crystal structure of t.th. hb8 ctp synthetase complex with sulfate2 anion 18 d1nyca_ 5.5 16 Fold:Streptavidin-like Superfamily:beta-Barrel protease inhibitors Family:Staphostatin 19 c2p9xB_ 5.2 28 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein ph0832; PDBTitle: crystal structure of ph0832 from pyrococcus horikoshii ot3

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0