|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | |
|
. | . | 70 | . | . | . | . | . | . | . | . | . | |
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |
|
|
|
|  |  |  |  |
|
|
|
| . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
T | L | L | T | L | R | D | V | H | I | N | F | P | A | R | K | N | W | L | G | K | T | T | E | H | V | H | A | I | N | G | I | D | L | Q | I | R | R | G | E | T | L | G | I | V | G | E | S | G | C | G | K | S | T | L | A | Q | L | L | M | G | M | L | Q | . |
. |
P | S | H | G | Q | Y | I | R | S | G | S | Q | . |
. |
Query Conservation |   |
  |
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |
|   |   |
|
|
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|
|   |   | . | . |   |   |   |
|   |
|   |   |   |
|   |   | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
|   |
|   |   |   |
|
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |
Template Sequence |   |
S | Q | L | E | I | R | D | L | W | A | S | I | D | G | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | I | L | K | G | V | N | L | V | V | P | K | G | E | V | H | A | L | M | G | P | N | G | A | G | K | S | T | L | G | K | I | L | A | G | D | P | E | Y | T | V | E | R | G | E | I | L | L | D | G | E | N | I | L |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  | T | T |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| S | S | S | S | S |  |  |  |  |  |  |  |  |  | T |
| T | T |
|  |  |  |  |  |  |  |  |  | T | T |  |  |
| T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 |
  |
  |   |
|
|
|
|
|
|
|
|
|
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | |
|
. | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | |
. | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
| . |
|
|  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | I | M | Q | M | V | F | Q | D | P | L | S | S | L | N | P | R | L | P | V | W | R | I | I | T | E | P | L | W | I | A | K | . |
. |
R | S | S | E | Q | Q | R | R | A | L | A | E | E | L | A | V | Q | V | G | I | R | P | E | Y | L | D | R | L | P | H | A | . |
F | S | G | G | Q |
Query Conservation |   |
. | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |
|
|
|
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
Template Sequence |   |
E | L | S | P | D | E | R | A | R | K | G | L | F | L | A | F | Q | Y | P | V | . |
. |
E | V | P | G | V | T | I | A | N | F | L | R | L | A | L | Q | A | K | L | G | R | E | V | G | V | A | E | F | W | T | K | V | K | K | A | L | E | L | L | D | W | D | E | S | Y | L | S | R | Y | L | N | E | G | F | S | G | G | E |
Template Known Secondary structure |   |
T | S |
|  |  |  |  |  |  | T | T | B |
|
|
|
|
|
|
| T | . | . | T |
|
| S |
| B |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| G | G | G | G | G | S | B | T | T | T | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | |
|
. | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . |
  |
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | |
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | Q | R | I | A | I | A | R | A | L | S | S | Q | P | D | V | I | V | L | D | E | P | T | S | A | L | D | I | S | V | Q | A | Q | I | L | N | L | L | V | T | L | Q | E | N | H | G | L | T | Y | V | L | I | S | H | N | V | S | V | I | R | H | M | . |
S | D | R | V | A | V | M | Y | L | G | Q | I | V | E | L | G | D |
Query Conservation |   |
  |
|
|
|   |
|
|   |
|
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   | . |   |
|
|
|   |
|
|   |   |
|   |
|
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|
|
|
|
|   |   |   |
|   |
|
|
|
|
|
|
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   | . |   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |
|   |
|   |   |   |
|   |
Template Sequence |   |
K | K | R | N | E | I | L | Q | L | L | V | L | E | P | T | Y | A | V | L | D | E | T | D | S | G | L | D | I | D | A | L | K | V | V | A | R | G | V | N | A | M | R | G | P | . |
N | F | G | A | L | V | I | T | H | Y | Q | R | I | L | N | Y | I | Q | P | D | K | V | H | V | M | M | D | G | R | V | V | A | T | G | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |
| G | G | G | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| B | T | . | T | B |  |  |  |  |  |  | S | S | S | G | G | G | G | T | S |
|
| S |  |  |  |  |  |  | T | T |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
149 | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | |
. | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
  |
  |   |
227 | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Q | Q | V | L | T | A | P | A | H | P | Y | T | R | L |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | E | L | A | L | E | L | E | A | K | G | Y | E | W | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . |
  |