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Job DescriptionP77783
Confidence100.00%DateThu Jan 5 12:32:48 GMT 2012
Rank6Aligned Residues744
% Identity21%Templatec1h0hA_
PDB info PDB header:dehydrogenaseChain: A: PDB Molecule:formate dehydrogenase (large subunit); PDBTitle: tungsten containing formate dehydrogenase from2 desulfovibrio gigas
Resolution1.8 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   43......50.........60.........70... ......80.........90.........100.........110.........120
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Query Sequence  VRAAEAPVEEKAVWSSCTVNCGSRCLLRLHV. . KDDTVYWVESDTTGDDVYGNHQVRACLRGRSIRRRMNHPDRLKYPMK
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Template Sequence  ATMALKTVDAKQTTSVCCY. CSVGCGLIVHTDKKTNRAINVEGDPD. . . . HPINEGSLCAKGASTWQLAENERRPANPLY
Template Known Secondary structure 




TTTTS
SS.BTT


TTT


TT....
TTTTT


TS
TTS
SS
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   1........10......... 20.........30.........40..... ....50.........60.........70.....
 
   121........130.........140.........150.........160 .........170.........180.........190.
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Query Sequence  RVGKRGEGKFERISWDEALDTISDNLRRILKDYGNEAVHV. . . . . . . . . LYGTGVDGGNITNSNVPYRLMNSCGGFLSRY
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Template Sequence  RAP. . GSDQWEEKSWDWMLDTIAERVAKTREATFVTKNAKGQVVNRCDGIASVGSAAMDNEECWIYQAWLRSLGLFYIEH
Template Known Secondary structure 
T..T
SS



TTS

S

TTS
TTB


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   76.. .80.........90.........100.........110.........120.........130.........140.........150...
 
   192.......200.........210 .........220.........230.........240.........250.........260.........270
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Query Sequence  GSYSTAQISAAMSYMFGAN. DGNSPDDIANTKLVVMFGNNPAETRMSGGGVTYYVEQARERSNARMIVIDPRYNDTAAGR
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Template Sequence  QARIHSATVAALAESYGRGAMTNHWIDLKNSDVILMMGSNPAENHPIS. . . FKWVMRAKDK. GATLIHVDPRYTRTST. K
Template Known Secondary structure  GGG

S

S
SS
TGGGGG
SS

STT...T.T

SS

TTGG.G
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   154.....160.........170.........180.........190.........200. ........210. ........220....... .
 
   271........280.........290.........300.........310 .......
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Query Sequence  EDEWLPIRPGTDGALACAIAWVLITENMVDQPFLDKYCVG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . YDEKTLP
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Template Sequence  CDLYAPLRSGSDIAFLNGMTKYILEKELYFKDYVVNYTNASFIVGEGFAFEEGLFAGYNKETRKYDKSKWGFERDENGNP
Template Known Secondary structure 
S


TT
TT
S
BGGGBBB
TT

TTTTTTTT
GGGG
B
B
TTS
B
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   230.........240.........250.........260.........270.........280.........290.........300.........
 
   318.320.........330.........340.........350.........360...... ...370.........380.........390...
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Query Sequence  ANAPRNAHYKAYILGEGPDGIAKTPEWAAKITSIPAEKIIQLAREIGSA. . . . KPAYICQGWGPQRHSNGEQTSRAIAML
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Template Sequence  KRDETLKHPRCVFQIMKKHYERYDLDKISAICGTPKELILKVYDAYCATGKPDKAGTIMYAMGWTQHTVGVQNIRAMSIN
Template Known Secondary structure 
B
TTS
STTBTT




GGGSTT





SS
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   310.........320.........330.........340.........350.........360.........370.........380.........
 
   394.....400.........410........ .420.........430........
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Query Sequence  SVLTGNVGINGGNSGVREGSWDLGV. . . . . . . . . . . EWFPMLENPVKTQISVFTWT. . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  QLLLGNIGVAGGGVNALRGEANVQGSTDHGLLMHIYPGYLGTARASIPTYEEYTKKFTPVSKDPQSANWWSNFPKYSASY
Template Known Secondary structure  TT
SSSTT
S

SBTTTT
BTTTTT

BTT

S





TT


GGGG
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   390.........400.........410.........420.........430.........440.........450.........460.........
 
   439440.........450.........460.........470.........480.........490.........500....
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Query Sequence  . . . . . . . . . . . . . . DAIDHGTEMTATRDGVRGKEKLDVPIKFLWCYASNTLINQHGDINHTHEVLQDDSKCEMIVGIDHF
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Template Conservation                                         

       

    
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Template Sequence  IKSMWPDADLNEAYGYLPKGEDGKDYSWLTLFDDMFQGKIKGFFAWGQNPACSGA. . . . NSNKTREALTKLDWMVNVNIF
Template Known Secondary structure 
TTS
S

B
TT


STT


S

SB....STT
SSS
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   470.........480.........490.........500.........510.........520.... .....530.........540.....
 
   505....510.. .......520.........530.........540.........550.........560........
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Query Sequence  MTASAKYC. . . . . . . . . . . . . DILLPDLMPTEQEDLISHESAGNMGYVILAQPATSAKFERKPIYWMLSEVAKRLGP. . .
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Template Sequence  DNETGSFWRGPDMDPKKIKTEVFFLPCAVAIEKEGSISNSGRW. . . . MQWRYVGPEPRKNAIPDGDLIVELAKRVQKLLA
Template Known Secondary structure 

TTTTGGGSTT

GGG


B

GGG


TT
....

SS


TT
B
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   546...550.........560.........570.........580........ .590.........600.........610.........620.
 
   569570.........580........ .590.........600.........610....
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Query Sequence  . . . . . . . . . . . . . . . DVYQTFTEGRSQHEWIKYLH. . . . . . . . . . AKTKERNPEMPDYEEMKTTGIFKKKC. . . . . . . . .
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Template Conservation                                                                  
               
Template Sequence  KTPGKLAAPVTKLKTDYWVNDHGHFDPHKIAKLINGFALKDFKVGDVEYKAGQQIATFGHLQADGSTTSGCWIYTGSYTE
Template Known Secondary structure  S
TT

S
GGGGB
TTS
B

BBSS
TT
TT
B
S
GGG

TTS
B

SSGGGTTST
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   622.......630.........640.........650.........660.........670.........680.........690.........700.
 
   615....620.........630...
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PEEHYVAFRAFREDPQANP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  .............................                   ................................
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Template Conservation                               
                                                  
Template Sequence  KGNMAARRDKTQTDMQAKIGLYPGWTWAWPVNRRIIYNRASVDLNGKPYAPEKAVVEWNAAEKKWVGDVPDGPWPPQADK
Template Known Secondary structure  TGGG
B




T

TTBSTTTT
SSTTGGGGB
TTS
BS
GGG
STTTTS

SS
S

TT
T
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   702.......710.........720.........730.........740.........750.........760.........770.........780.
 
   634.....640.........650.. .......660.........670.........680.........690.......
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Query Sequence  . . . . . . . LKTPSGKIEIYSERLAKIA. . . . . . . . . DTWELKKDEIIHPLPAYTPGFDGWDDPLRKTYPLQLTGFHYKART
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Template Conservation              
              
    
                                 

  
 
 
     
Template Sequence  EKGKRAFIMKPEGYAYLYGPGREDGPLPEYYEPMECPVIEHPFSKTLHNPTALHFATEEKAVCDPRYPFICSTYRVTEHW
Template Known Secondary structure  TT


S
TTSSSS
B
SS
TTSTT
SS






SSS



SS
S

S
TT

SS

SS




TTS


TT

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   782.......790.........800.........810.........820.........830.........840.........850.........860.
 
   698. 700.........710.. .......720.........730.........740.........750.........760..... ....770.
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Query Sequence  HS. . SYGNIDVLQQACP. QEVWINPIDAQARGIRHGDTVRVFNNNGEMLIAAKVTPRILPGVTAIGQGAWL. . . KADMFG
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Template Conservation 

   
 
   
    
   
 


 

  



 

 
 
 
  
 
   
 

  
 

 
       
  
   
  
Template Sequence  QTGLMTRNTPWLLEAEPQMFCEMSEELATLRGIKNGDKVILESVRGKLWAKAIITKRIKPFAIQGQQVHMVGIPWHYGWS
Template Known Secondary structure  TTSTSS
S

T

TT
TT
TT


TT
S


TT
Template Predicted Secondary structure 








































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   862.......870.........880.........890.........900.........910.........920.........930.........940.
 
   772.......780.........790.........800......
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Query Sequence  DRVDHGGSINILTSHRPSPLAKGNPSHSNLVQIEK
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Template Conservation       
   
 

    

 

    
   
 
 
Template Sequence  FPKNGGDAANILTPSVGNPNTGIPETKAFMVNVTK
Template Known Secondary structure  SSTTS


GGGS

BSSS
SSBSB

S
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   942.......950.........960.........970......
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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