|   |
13 | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | V | L | Y | A | D | E | L | A | K | L | K | Q | N | D | N | A | P | C | P | P | G | W | Q | L | S | L | P | A | A | R | A | F | I | . |
. |
. |
. |
. |
. |
. |
L | G | D | E | A | Q | N | I | S | R | K | V | V | I | S | P | S | A | V | E | R | M | L | V | T | L | A | T | G | R | G | L | M | L | V | G | E | P |
Query Conservation |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
|   |
|
|   |
Template Sequence |   |
G | S | V | D | T | A | V | K | A | I | K | K | G | A | Y | E | F | L | E | K | P | F | S | V | E | R | F | L | L | T | I | K | H | A | F | E | E | Y | S | K | K | A | P | P | Q | E | E | I | E | F | V | G | E | H | P | K | I | L | E | I | K | R | L | I | P | K | I | A | K | S | K | A | P | V | L | I | T | G | E | S |
Template Known Secondary structure |   |
S |
|
|  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
|
|
|
|
|
|
|
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| S |
|  |  |  |  |
|
| T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
  |
  |   |
86 | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | T | A | K | S | L | L | S | E | L | L | A | T | A | I | S | G | D | A | G | L | T | I | Q | G | G | A | S | T | T | E | D | Q | I | K | Y | G | W | N | Y | A | L | L | I | N | H | G | P | S | T | E | A | L | V | P | A | P | L | Y | Q | G | M | R | D | G | K | I | V | R | F | E | E | I | T | R | T | P | L | E | V |
Query Conservation |   |
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   |   |   |
|   |   |
|
|   |   |
| . |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
| . | . |   |   |
|
|
|   |
|   |   |
|   |   |
|   |   |   |   |
Template Sequence |   |
G | T | G | K | E | I | V | A | R | L | I | H | R | Y | S | . |
G | R | K | G | A | F | V | D | L | N | C | A | S | I | P | Q | E | L | A | E | S | E | L | F | G | H | E | K | G | A | F | T | G | A | L | T | R | K | K | G | K | L | E | L | A | . |
. |
D | Q | G | T | L | F | L | D | E | V | G | E | L | D | Q | R | V |
Template Known Secondary structure |   |
T | S | S |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
| S |
|  |  |  |  |  | S | S | S | S |
| T | T | T |  |  |  |  |  |  |  |  |
| S |
| S | S | S | S |
|
|
|
|  |  |
|  |  |  |  | T | . | . | T | T | S |  |  |  |  |  | T | G | G | G | S |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
| . | . |
|
|
|  |  |  |  |  |
|  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
163 | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | |
. | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | |
|
. | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
  |
  |   |
166 | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
| . | . | . | . | . |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | D | C | L | L | G | M | L | S | D | R | V | M | T | G | P | E | L | T | G | E | A | S | Q | L | Y | A | R | E | G | F | N | I | I | A | T | A | N | T | . |
. |
. |
. |
. |
R | D | R | G | V | N | E | M | S | A | A | L | K | R | R | F | D | F | E | T | V | F | P | I | M | D | F | A | Q | E | L | E | L | V | A | S |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   | . | . | . | . | . |   |   |   |
|   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |
|   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |
Template Sequence |   |
Q | A | K | L | L | R | V | L | E | T | G | S | F | . |
. |
. |
. |
. |
T | R | L | G | G | N | Q | K | I | E | V | D | I | R | V | I | S | A | T | N | K | N | L | E | E | E | I | K | K | G | N | F | R | E | D | L | Y | Y | R | L | S | V | F | Q | I | Y | L | P | P | L | R | E | R | G | K | D | V | I | L | L | A | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | S |  |  | . | . | . | . | . |
|
| B | T |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  | S | S |
|  |  |  |  |  |  | T | T | S | S |
|  |  |  |  |  |  |  | T | S |  |  |  |  |
|
|
| G | G | G | S | T | T |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . |
  |
  |   |
241 | |
. | . | . | . | . | . | . | . | 250 | . | . | . | |
. | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . |
Predicted Secondary structure |   |
 | . |  |  |  |  |  |  |  |
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | . |
S | A | R | L | L | A | H | S | G | I | P | H | . |
K | V | P | D | A | V | L | E | L | L | V | R | T | F | R | D | L | R | A | N | G | E | K | K | T | S | M | D | T | L | T | A | I | M | S | T | A | E | A | V | N | V | A | H | A | V | G | V | R | A |
Query Conservation |   |
  | . |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|
|
|
|
|   |
|
|   |   |   |
|   |   |
|   |   |   |   |
Template Sequence |   |
Y | F | L | K | K | F | A | K | E | Y | K | K | N | C | F | E | L | S | E | E | T | K | E | Y | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
X | K | Q | E | W | K | G | N | V | R | E | L | K | N | L | I | E | R | A | V | I | L | C |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
| B |
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  | T |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
315 | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
  |