|   |
57 | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | K | V | V | I | S | P | S | A | V | E | R | M | L | V | T | L | A | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | R | G | L | M | L | V | G | E | P | G | T | A | K | S | L | L | S | E | L | L | A | T | A | I | S | G | D | A | G | L | T | I | Q | G | G | A | S | T | T | E | D | Q | I | K | Y | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|
|   |
|   |
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|   |
|
|   |   |   |
|   |   |
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
Template Sequence |   |
S | D | V | A | G | L | E | G | A | K | E | A | L | K | E | A | V | I | L | P | I | K | F | P | H | L | F | T | G | K | R | T | P | W | R | G | I | L | L | F | G | P | P | G | T | G | K | S | Y | L | A | K | A | V | A | T | E | A | N | N | S | T | F | F | S | I | S | S | S | D | L | V | S | . |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
G | G | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | S |
| T | T |
|
|
|
| S |  |  |  |  |  | S | S | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |
|
| S | S |
|
| . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |
|
| . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
134 | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | |
|
|
|
|
|
|
  |
  |   |
123 | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | N | Y | A | L | L | I | N | H | G | P | S | T | E | A | L | V | P | A | P | L | Y | Q | G | M | R | D | G | K | I | V | R | F | E | E | I | T | R | T | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | E | V | Q | D | C | L | L | G | M | L | S | D | R | V | M | T | G | P | E | L | T | G | E | A | S | Q | L | Y |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
K | W | L | G | E | S | E | K | L | V | K | N | L | F | Q | L | A | R | E | N | K | P | S | I | I | F | I | D | E | I | D | S | L | C | G | S | R | S | E | N | E | S | E | A | A | R | R | I | K | T | E | F | L | V | Q | M | Q | G | V | G | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . | . | S | S |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S |  |  |  |  |  |  | T | T | T | G | G | G |
|
| S | S | S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
207 | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
192 | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | R | E | G | F | N | I | I | A | T | A | N | T | R | D | R | G | V | N | E | M | S | A | A | L | K | R | R | F | D | F | E | T | V | F | P | I | M | D | F | A | Q | E | L | E | L | V | A | S | A | S | A | R | L | L | A | H | S | G | I | P | H | K | V | P | D | A | V | L | E | L | L | V | R | T | F | R | D | L | R |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|
|   |
|
|
|   |   |   |   | . | . | . | . |
|
|   |
|
|   |
|
|
|   |   |   |
|   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Template Sequence |   |
D | N | D | G | I | L | V | L | G | A | T | N | I | P | W | V | . |
. |
. |
. |
L | D | S | A | I | R | R | R | F | E | K | R | I | Y | I | P | L | P | E | P | H | A | R | A | A | M | F | K | L | H | L | G | T | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | N | S |
Template Known Secondary structure |   |
|
| T | T |  |  |  |  |  |  |  | S |
| T | T | T | . | . | . | . | S |
|  |  |  |  |  | T |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| B |
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  | . | . | . | . |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
268 | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | |
|
|
|
. | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 320 |
  |
  |   |
272 | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
A | N | G | E | K | K | T | S | M | D | T | L | T | A | I | M | S | T | A | E | A | V | N | V | A | H | A | V | G | V | R | A | W | F | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|   |   |
|   |   |
|
|   |   |
|   |
|   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | T | E | A | D | F | R | E | L | G | R | K | T | D | G | Y | S | G | A | D | I | S | I | I | V | R | D | A | L | M | Q | P | V | R | K | V | Q | S | A | T | H | F | K | K | V | R | G | P | S | R | A | D | P | N | H | L | V | D | D | L | L | T | P | C | S | P | G | D | P | G | A | I | E | M | T | W | M | D | V | P |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  | T |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |
| S | S |
| T | T | S |  |  |  |  |  |  |  |  |
|
| S | S | S | T | T |  |  |  |
|
| G | G | G | S |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
321 | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 |
  |
  |   |
|
|
|
|
307 | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
Predicted Secondary structure |   |
. | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
A | N | R | A | G | E | P | A | D | L | V | E | C | I | A | G | T | I | V | K | D | N | E | E | D | R | A | R | L | R | R | Y | F | E | Q |
Query Conservation |   |
. | . | . | . |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | D | K | L | L | E | P | V | V | S | M | S | D | M | L | R | S | L | S | N | T | K | P | T | V | N | E | H | D | L | L | K | L | K | K | F | T | E | D |
Template Known Secondary structure |   |
G | G | G | B |
|
|
|
| B |
|  |  |  |  |  |  |  |  |  | T |
|
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
401 | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . |
  |