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Job DescriptionP27296
Confidence99.51%DateThu Jan 5 11:43:42 GMT 2012
Rank37Aligned Residues245
% Identity20%Templatec2wv9A_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:flavivirin protease ns2b regulatory subunit, flavivirin PDBTitle: crystal structure of the ns3 protease-helicase from murray2 valley encephalitis virus
Resolution2.75 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   43......50.........60.........70.........80.........90.........100.........110.........120..
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Query Sequence  AGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKKIIPDLKFTAAFGRGRYVCPR
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Template Sequence  MLKKRQLTVLDLHPGAGKTRRILPQIIKDAIQKRLRTAVLAPTRVVAAEMA. . . . . . . . EALRGLPVRYLTPREHS. . . .
Template Known Secondary structure  GGSTT



TTTTTTTTTT

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   183......190.........200.........210.........220.........230... ......240.........250
 
   123......130.........140.........150.........160.........170.........180.........190.........200..
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Query Sequence  NLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLKGDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYY
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   203......210.........220.........230.........240.........250.........260.........270.........280..
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Query Sequence  RECPFFVARREIQEAEVVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQLDLFTKL
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Template Sequence  . . . . . . . . . . . . GNEIVDVMCHATLTHRLMSPLRV. . PNYNLFVMDEAH. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   254.....260.........270...... ...280........
 
   283......290.........300.........310.........320.........330.........340.........350.........360..
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Query Sequence  VATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEHRFAMGELPDEVLEICQRLAKLTEMLRGL
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   363......370.........380.........390.........400.........410.........420.........430.........440..
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Query Sequence  AELFLNDLSEKTGSHDIVRLHRLILQMNRALGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSD
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . FTDPASIAARGYIA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   289290.........300..
 
   443......450.........460.........470.........480.........490.........500.........510.........520..
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Query Sequence  QLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPSIDNEEQHIAEMA
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Template Sequence  . . . TRVEAGEAAAIFMTATPPGT. . . . . . . . . . . . . . . . . . . . . . . SDPFPDTNSPVHDVSSEIPDRAWSSGFEWITD. .
Template Known Secondary structure  ...TTS

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   303......310.........320.. .......330.........340.........350....
 
   523......530.........540.........550.........560.........570.........580.........590.........600..
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Query Sequence  AFFRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGDQPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKG
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Template Sequence  . . . . . . . . . . YAGKTVWFVASVKMSNEIAQCLQRAGKRVIQLNRKSYDTEYPKCK. . . . NGDWDFVITTDISEMGANF. .
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SSTTT


SSSGGGGG....T


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   355....360.........370.........380.........390......... 400.........410........
 
   603......610.....
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Query Sequence  DLLSQVHIHKIAF
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Template Sequence  G. ASRVIDCRKSV
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   419 420.........430
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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