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Job DescriptionP27296
Confidence99.53%DateThu Jan 5 11:43:42 GMT 2012
Rank35Aligned Residues319
% Identity22%Templatec2vsxA_
PDB info PDB header:translation/hydrolaseChain: A: PDB Molecule:atp-dependent rna helicase eif4a; PDBTitle: crystal structure of a translation initiation complex
Resolution2.8 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   12.......20.........30.........40.........50.........60.........70...... ...80.........
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Query Sequence  AAWYKALQEQIPDFIPRAPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQ. . KTLVVSTANVALQ
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Template Conservation    
   
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Template Sequence  ENLLRGVFG. YGFEEPSAIQQRAIMPII. . . . . . EGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELA
Template Known Secondary structure  T.TT

S

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TTSS

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   31........ 40.........50....... ..60.........70.........80.........90.........100...
 
   90.........100.........110.........120.........130.........140.........150.........160.........
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Query Sequence  DQIYSKDLPLLKKIIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLKGDLDTYKWD
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Template Sequence  LQIQKV. . . . VMALAFHMDIKVHACIGL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ....TSSS





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   104..... 110.........120.......
 
   170.........180.........190.........200.........210.........220.........230.........240.........
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Query Sequence  GLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMESEAVLPDPKNLLLVLDE
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Template Conservation  .............................................        
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RDAQIVVGTPGRVFDNIQRRRFRTD. KIKMFILDE
Template Known Secondary structure  .............................................SS
S
TT
S

T.T

S
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   138.140.........150.........160.. .......170.
 
   250.........260.........270.........280.........290.........300.........310.........320.........
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Query Sequence  GHHLPDVARDALEMSAEITAPWYRLQLDLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAG
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Template Conservation        ..........................................................................
Template Sequence  ADEMLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   172.....
 
   330.........340.........350.........360.........370.........380.........390.........400.........
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Query Sequence  QEAEHRFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRALGMFEAQSKLWRLASLA
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   410.........420.........430.........440.........450.........460.........470.........480.........
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Query Sequence  QSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALD
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Template Conservation  ..........................                             ...               
      
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . SGFKEQIYQIFTLLPPTTQVVLLSATMPN. . . DVLEVTTKFMRNPVRILVKKDE
Template Known Secondary structure  ..........................TT
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   178.180.........190.........200...... ...210.........220........
 
   490.........500.........510.........520.........530.........540.........550.........560.........
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Query Sequence  SPFNHCEQGKIVIPRMRVEPSIDNEEQHIAEMAAFFRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGDQPR
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Template Conservation                   .............                                                  
Template Sequence  LTLEGIKQFYVNVEEEE. . . . . . . . . . . . . YKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLP
Template Known Secondary structure 

STTSGG.............GS

S
SSTT


TTS
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   229230.........240..... ....250.........260.........270.........280.........290.....
 
   570.........580.........590.........600.........610.........620.........630.........640.........
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Query Sequence  YRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFN
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Template Sequence  QQERDTIMKEFRSGSSRILISTDLLARGIDVQ. . QVSLVINYDLPA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NKEN
Template Known Secondary structure  TTTS
SSGGGSS



..S

SS

S..............................SGGG
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   296...300.........310.........320....... ..330......... 340...
 
   650.........660.........670...
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Query Sequence  LIQQVGRLIRSHGCWGEVVIYDKR
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Template Sequence  YIHRIGRKGV. . . . . . AINFVTNE
Template Known Secondary structure  G


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   344.....350... ......360.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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