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Job DescriptionP27296
Confidence99.65%DateThu Jan 5 11:43:42 GMT 2012
Rank25Aligned Residues277
% Identity25%Templatec2jlrA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:serine protease subunit ns3; PDBTitle: dengue virus 4 ns3 helicase in complex with amppnp
Resolution2.0 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   45....50.........60.........70.........80.........90.........100.........110.........120....
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Query Sequence  EEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKKIIPDLKFTAAFGRGRYVCPRNL
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Template Sequence  RKKRLTIMDLHPGAGKTKRILPSIVREALKRRLRTLILAPTRVVAAEMEEA. . . . LRGLPIRYQTPAVKSDHT. . . . . . .
Template Known Secondary structure  STT



TTSSTTTTTT

SS....TTTS


TTSS



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   184.....190.........200.........210.........220.........230.... .....240.........250..
 
   125....130.........140.........150.........160.........170.........180.........190.........200....
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Query Sequence  TALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLKGDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRE
Query Conservation                                                                
           
     
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   205....210.........220.........230.........240.........250.........260.........270.........280....
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Query Sequence  CPFFVARREIQEAEVVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQLDLFTKLVA
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Template Sequence  . . . . . . . . . . GREIVDLMCHATFTTRLLSSTRVPNY. . NLIVMDEAHFTDPCSVAARGYISTR. . . . . . . . . . . . . . . . .
Template Known Secondary structure  ..........SSS

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..SSTT

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   253......260.........270........ .280.........290.........300...
 
   285....290.........300.........310.........320.........330.........340.........350.........360....
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Query Sequence  TCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEHRFAMGELPDEVLEICQRLAKLTEMLRGLAE
Query Conservation                     
      
                                               
     
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   365....370.........380.........390.........400.........410.........420.........430.........440....
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Query Sequence  LFLNDLSEKTGSHDIVRLHRLILQMNRALGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQL
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   445....450.........460.........470.........480.........490.........500.........510.........520....
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Query Sequence  ERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPSIDNEEQHIAEMAAF
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Template Sequence  . . . VEMGEAAAIFMTATPPGSTD. . . . . . . . . . . . . . . . . . . . . . . PFPQSNSPIEDIEREIPERSWNTGFDWITDY. . .
Template Known Secondary structure  ...TTS

SS
TT


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   304.....310.........320... ......330.........340.........350....
 
   525....530.........540.........550.........560.........570.........580.........590.........600.
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Query Sequence  FRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGDQPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLK. . .
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Template Sequence  . . . . . . . . . QGKTVWFVPSIKAGNDIANCLRKSGKRVIQLSRKTFDTEYPKTK. . . . LTDWDFVVTTDISEMGANFRAGR
Template Known Secondary structure  .........
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SSTT


TTTGGGGG....SS

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GGGGTT




S
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   355....360.........370.........380.........390........ .400.........410.........420.
 
   602.......610.........620.........630.........640.........650.........660.......
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Query Sequence  . . . . . . . . . . . . . . GDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEV
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Template Sequence  VIDPRRCLKPVILTDGPERVILAGPIPVTP. . . . . . . . . . . . . . . . . . . . . . . . . . . ASAA. . . QRRGRIGRNPAQEDDQ
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SSS


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TT


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   422.......430.........440.........450. .... ....460.........470.
 
   668.670...
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Query Sequence  VIYDKR
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Template Conservation        
Template Sequence  YVFSGD
Template Known Secondary structure 
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No model constructed - rank, confidence too low




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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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