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Job DescriptionP27296
Confidence99.74%DateThu Jan 5 11:43:42 GMT 2012
Rank11Aligned Residues395
% Identity20%Templatec1wp9D_
PDB info PDB header:hydrolaseChain: D: PDB Molecule:atp-dependent rna helicase, putative; PDBTitle: crystal structure of pyrococcus furiosus hef helicase domain
Resolution2.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   25....30.........40.........50.........60.........70.........80.........90.........100....
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Query Sequence  FIPRAPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKKII
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Template Conservation    

 

   
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Template Sequence  IQPRIYQEVIYAKCK. . . . . . . ETNCLIVLPTGLGKTLIAMMIAEYRLTKYGGKVLMLAPTKPLVLQHAES. . . . FRRLF
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GG.......GS


TTS
S
S

SS....B
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   8.10.........20.. .......30.........40.........50.........60.........70. .....
 
   105 ....110.........120.........130.........140.........150.........160.........170.........180..
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Query Sequence  P. . DLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLKGDLDTYKWDGLRDHTDIAIDDD
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Template Sequence  NLPPEKIVALTGEKS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure 
S
GGG
S
S
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   77..80.........90.
 
   183......190.........200.........210.........220.........230.........240.........250.........260..
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Query Sequence  LWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALE
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Template Conservation  ........................            
   
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . PEERSKAWARAKVIVATPQTIENDLLAGRISLE. DVSLIVFDEAHRAVGNYAYVFI
Template Known Secondary structure  ........................
S
TTS

TT.S
STGGG
STT
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   92.......100.........110.........120.... .....130.........140......
 
   263.. ....270.........
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Query Sequence  MSA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EITAPWYRLQLDLF
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Template Conservation                    
              
                                              
Template Sequence  AREYKRQAKNPLVIGLTASPGSTPEKIMEVINNLGIEHIEYRSENSPDVRPYVKGIRFEWVRVDLPEIYKEVRKLLREML
Template Known Secondary structure 
SS

S
S
SST



TTSTTTGGGS






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   147..150.........160.........170.........180.........190.........200.........210.........220......
 
   280.........290.........300.........310.........320.........330.........340.........350.........
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Query Sequence  TKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEHRFAMGELPDEVLEICQRLAKLTEML
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Template Conservation                                        .............                             
Template Sequence  RDALKPLAETGLLESSSPDIPKKEVLRAGQIINEEMAK. . . . . . . . . . . . . GNHDLRGLLLYHAMALKLHHAIELLETQG
Template Known Secondary structure  TSSS


TTS
TT.............T

STTTT
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   227..230.........240.........250.........260.... .....270.........280.........290...
 
   360.........370.........380.........390.........400.........410.........420.........430.........
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Query Sequence  RGLAELFLNDLSEKTGSHDIVRLHRLILQMNRALGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIR
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Template Conservation                                           .......................................
Template Sequence  LSALRAYIKKLYEEAKAKASKEIFSDKRMKKAISLLVQAKE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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TS.......................................
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   294.....300.........310.........320.........330....
 
   440.........450.........460.........470.........480.........490.........500.........510.........
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Query Sequence  VSDQLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPSIDNEEQHIA
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Template Conservation  .......................................................................         
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . IGLDHPKMD
Template Known Secondary structure  .......................................................................TT
S
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   338.340......
 
   520.........530.........540.........550.........560.........570.........580.........590.........
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Query Sequence  EMAAFFRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGDQPRYRLVELHRKRVANGERSVLVGLQSFAEGLD
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Template Sequence  KLKEIIREQLQRKQNSKIIVFTNYRETAKKIVNELVKDGIKAKR. . FREQKLILDEFA. . . . RGEFNVLVATSVGEEGLD
Template Known Secondary structure 
TT


S
TT

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....TS
S
GGGGGGGG
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   347..350.........360.........370.........380.........390 .........400.. .......410.........420
 
   600.........610.........620.........630.........640.........650.........660.........670.........
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Query Sequence  LKGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNY
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Template Conservation 
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Template Sequence  VP. . EVDLVVFYEPVPS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AIRSIQRRGRTGRHMPGRVIILMAKGTRDEAYY
Template Known Secondary structure  ST..T

SS

..............................TTS
S


STTS
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   435. ...440......... 450.........460.........470.........480..
 
   680.
Predicted Secondary structure 
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Query Sequence  GK
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Template Conservation    
Template Sequence  WS
Template Known Secondary structure 
Template Predicted Secondary structure 
Template SS confidence 

   483.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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