Secondary structure and disorder prediction

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10

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20

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30

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Sequence

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T

T

S

M

L

N

A

K

L

L

P

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A

A

V

V

V

V

R

V

V

V

V

V

G

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A

P

Secondary structure

SS confidence

Disorder

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Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1v9c chain A Region: 25 - 32 Aligned: 8 Modelled: 8 Confidence: 16.8% Identity: 75% Fold: Flavodoxin-like Superfamily: Precorrin-8X methylmutase CbiC/CobH Family: Precorrin-8X methylmutase CbiC/CobH Phyre2 PDB 1f2v chain A Region: 25 - 32 Aligned: 8 Modelled: 8 Confidence: 13.1% Identity: 75% Fold: Flavodoxin-like Superfamily: Precorrin-8X methylmutase CbiC/CobH Family: Precorrin-8X methylmutase CbiC/CobH Phyre2 PDB 2afv chain B Region: 25 - 32 Aligned: 8 Modelled: 8 Confidence: 12.5% Identity: 63% PDB header:isomerase Chain: B: PDB Molecule:cobalamin biosynthesis precorrin isomerase; PDBTitle: the crystal structure of putative precorrin isomerase cbic2 in cobalamin biosynthesis Phyre2 PDB 3e7d chain C Region: 25 - 32 Aligned: 8 Modelled: 8 Confidence: 11.9% Identity: 63% PDB header:isomerase Chain: C: PDB Molecule:cobh, precorrin-8x methylmutase; PDBTitle: crystal structure of precorrin-8x methyl mutase cbic/cobh from2 brucella melitensis Phyre2 PDB 1ou0 chain A Region: 25 - 32 Aligned: 8 Modelled: 8 Confidence: 11.8% Identity: 75% Fold: Flavodoxin-like Superfamily: Precorrin-8X methylmutase CbiC/CobH Family: Precorrin-8X methylmutase CbiC/CobH Phyre2 1 d1v9ca_ 2 d1f2va_ 3 c2afvB_ 4 c3e7dC_ 5 d1ou0a_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1v9ca_ 16.8 75 Fold:Flavodoxin-like Superfamily:Precorrin-8X methylmutase CbiC/CobH Family:Precorrin-8X methylmutase CbiC/CobH 2 d1f2va_ 13.1 75 Fold:Flavodoxin-like Superfamily:Precorrin-8X methylmutase CbiC/CobH Family:Precorrin-8X methylmutase CbiC/CobH 3 c2afvB_ 12.5 63 PDB header:isomerase Chain: B: PDB Molecule:cobalamin biosynthesis precorrin isomerase; PDBTitle: the crystal structure of putative precorrin isomerase cbic2 in cobalamin biosynthesis 4 c3e7dC_ 11.9 63 PDB header:isomerase Chain: C: PDB Molecule:cobh, precorrin-8x methylmutase; PDBTitle: crystal structure of precorrin-8x methyl mutase cbic/cobh from2 brucella melitensis 5 d1ou0a_ 11.8 75 Fold:Flavodoxin-like Superfamily:Precorrin-8X methylmutase CbiC/CobH Family:Precorrin-8X methylmutase CbiC/CobH

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0