|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
|
. | . | . | . | . | 70 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | . | . | . | . | . |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | A | I | T | G | A | T | G | Q | L | G | H | Y | V | I | E | S | L | M | K | T | V | P | A | S | Q | I | V | A | I | V | R | N | P | A | K | A | Q | A | L | A | . |
. |
. |
. |
. |
A | Q | G | I | T | V | R | Q | A | D | Y | G | D | E | A | A | L | T | S | A | L | Q | . |
. |
G | V | E | K | L | L | L | I | S | S |
Query Conservation |   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |
|   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |
|   |   | . | . |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|
|   |   | . | . |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
Template Sequence |   |
V | F | V | T | G | H | T | G | F | K | G | S | W | L | S | L | W | L | T | E | M | . |
. |
G | A | I | V | K | G | Y | A | L | D | A | P | T | V | P | S | L | F | E | I | V | R | L | N | D | L | M | E | S | H | I | G | D | I | R | D | F | E | K | L | R | S | S | I | A | E | F | K | P | E | I | V | F | H | M | A | A |
Template Known Secondary structure |   |
 |  |  |  | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | T |
|  |  |  |  |  |  | S | S |
| S | S | S | S |
|  |  |  |  | T | T | G | G | G | T | S |  |  |  |  |
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
14 | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | |
|
. | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . |
  |
  |   |
75 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | |
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
S | E | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Q | R | A | P | Q | H | R | N | V | I | N | A | A | K | A | A | G | V | K | F | I | A | Y | T | S | L | L | H | A | D | T | S | P | L | G | L | A | D | E | H | I | E | T | E | K | M | L | A | D | S | G | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
Q | P | L | V | R | L | S | Y | E | Q | P | I | K | T | Y | S | T | N | V | M | G | T | V | H | L | L | E | T | V | K | Q | V | G | N | I | K | A | V | V | N | I | T | S | D | K | C | Y | D | N | R | E | W | V | W | G | Y | R | E | N | E | P | M | G | G | Y | D | P | Y | S | N | S | K | G | C | A | E | L | V | A | S |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
| G | G | G | B |
|
|
|
| S | S | S |
| B |
| T | T | S |
| B |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
131 | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | Y | T | L | L | R | N | G | W | Y | S | E | N | Y | L | A | S | A | P | A | A | L | E | H | G | V | F | I | G | A | A | G | D | G | K | I | A | S | A | T | R | A | D | Y | A | A | A | A | A | R | V | I | S | E | A |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
A | F | R | N | S | F | F | N | P | A | N | Y | E | Q | H | G | V | G | L | A | S | V | R | A | G | N | V | I | G | G | G | D | W | A | K | D | R | L | I | P | D | I | L | R | S | F | E | N | N | Q | Q | V | I | I | R | N | P | Y | S | I | R | P | W | Q | H | V | L | E | P | L | S | G | Y | I | V | V | A | Q | R | L |
Template Known Secondary structure |   |
 |  |  |  |  |  | S |
| G | G | G |  |  |  |  |
|
|  |  |  |  |  |  |  |
|  |  |  |
| T | T |
|
|
| T | T |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  | S |
| T | T |
| B |
|
|  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
172 | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . |
  |
  |   |
186 | . | . | . | 190 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | H | E | G | K | . |
. |
. |
. |
. |
. |
V | Y | E | L | A | G | D | S | A | W | T | L | T | Q | L | A | A | E | L | T | K | Q | S | G | K | Q | V | T | Y | Q | N | L | S | E | A | D | F | A | A | A | L | K | S | V | G | L | P | D | G | L | A | D | M | L | A | D | S | D | V | G | A | S | K | G | G | L | F | D | D |
Query Conservation |   |
  |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
Template Sequence |   |
Y | T | E | G | A | K | F | S | E | G | W | N | F | G | P | R | D | E | D | A | K | T | V | E | F | I | V | D | K | M | V | T | L | W | G | D | D | A | S | W | L | L | D | P | H | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | H | Y | L | K | L | D |
Template Known Secondary structure |   |
 |  |
|  |  |  |  |
| S |  |  |  |  |
|
|
| G | G | G |
|
| B |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S | B |
|
| B |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 300 | . | . | . | . |
  |
  |   |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
. | . | . | . | . | . | . | 280 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | K | T | L | S | K | L | I | G | H | P | T | T | . |
T | L | A | E | S | V | S | H | L | F | N |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |
|   | . |   |
|   |
|   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |
|   |   |   |
|   |
Template Sequence |   |
C | S | K | A | N | M | Q | L | G | W | H | P | R | W | G | L | T | E | T | L | S | R | I | V | K |
Template Known Secondary structure |   |
|  |  |  |  |  |  | T |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . |
  |