|   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | |
|
|
|
. | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | N | D | T | D | G | I | V | R | V | A | E | S | V | I | P | E | I | K | H | Q | D | E | V | R | V | K | I | A | S | S | G | L | C | G | S | D | L | P | R | I | F | K | . |
. |
. |
. |
N | G | A | H | Y | Y | P | I | T | L | G | H | E | F | S | G | Y | I | D | A | V | G | S | G | V | D | D | L | H | P | G | D | A |
Query Conservation |   |
|   |   |   |   |
|   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|
|
|
|   |
|   |
|
|
|   |   |
|   |   |   |   |   |
| . | . | . | . |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |
|
|   |
|
|   |   |
|   |   |   |   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |
|
|   |
|
|   |   |
|   |   |   |   |
|
|
|
|
Template Sequence |   |
L | W | I | S | E | A | S | P | S | L | E | S | V | Q | K | G | E | E | L | K | E | G | E | V | T | V | A | V | R | S | T | G | I | C | G | S | D | V | H | F | W | K | H | G | C | I | G | P | M | I | V | E | C | D | H | V | L | G | H | E | S | A | G | E | V | I | A | V | H | P | S | V | K | S | I | K | V | G | D | R |
Template Known Secondary structure |   |
 |  |  |  |  |
| S | S |
|  |  |  |  |  |  | T |
| S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  | S | B | S | S | S |
| B |
|
| S |
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |
| T | T |
|
| S |
|
| T | T |
|  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | A | C | V | P | L | L | P | C | F | T | C | P | E | C | L | K | G | F | Y | S | Q | C | A | K | Y | D | F | I | G | S | R | R | D | G | G | F | A | E | Y | I | V | V | K | R | K | N | V | F | A | L | P | T | D | M | P | I | E | D | G | A | F | I | E | P | I | T | V | G | L | H | A | F | H | L | A | Q | G | C | E |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | A | I | E | P | Q | V | I | C | N | A | C | E | P | C | L | T | G | R | Y | N | G | C | E | R | V | D | F | L | S | T | P | P | V | P | G | L | L | R | R | Y | V | N | H | P | A | V | W | C | H | K | I | G | N | M | S | Y | E | N | G | A | M | L | E | P | L | S | V | A | L | A | G | L | Q | R | A | G | V | R | L |
Template Known Secondary structure |   |
 |  |  |
|
|  |  |
|
| S |
| S |  |  |  |  | T | T |
| G | G | G |
| T | T |
|  |  | T | T | S | T | T | S |
|
| S |
| B | S |  |  |  |  |  | G | G | G |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| T |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . |
  |
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | |
|
|
|
. | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | K | N | V | I | I | I | G | A | G | T | I | G | L | L | A | I | Q | C | A | V | A | L | G | A | K | S | V | T | A | I | D | I | S | S | E | K | L | A | L | A | K | S | F | G | A | M | Q | T | F | N | S | S | E | M | S | . |
. |
. |
. |
A | P | Q | M | Q | S | V | L | R | E | L | R | F | N | Q | L | I | L | E | T |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
Template Sequence |   |
G | D | P | V | L | I | C | G | A | G | P | I | G | L | I | T | M | L | C | A | K | A | A | G | A | C | P | L | V | I | T | D | I | D | E | G | R | L | K | F | A | K | E | I | C | P | E | V | V | T | H | K | V | E | R | L | S | A | E | E | S | A | K | K | I | V | E | S | F | G | G | I | E | P | A | V | A | L | E | C |
Template Known Secondary structure |   |
T |
|
|  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  | T | S | S |
|
|
| S |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . |
  |
  |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | V | P | Q | T | V | E | L | A | V | E | I | A | G | P | H | A | Q | L | A | L | V | G | T | L | H | Q | D | L | H | L | T | S | A | T | F | G | K | I | L | R | K | E | L | T | V | I | G | S | W | M | N | Y | S | S | P | W | P | G | Q | E | W | E | T | A | S | R | L | L | T | E | R | K | L | S | L | E | P | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   |   |
Template Sequence |   |
T | G | V | E | S | S | I | A | A | A | I | W | A | V | K | F | G | G | K | V | F | V | I | G | V | G | K | N | E | I | Q | I | . |
. |
. |
P | F | M | R | A | S | V | R | E | V | D | L | Q | F | Q | Y | R | Y | C | . |
. |
. |
. |
. |
. |
N | T | W | P | R | A | I | R | L | V | E | N | G | L | V | D | L | T | R | L |
Template Known Secondary structure |   |
S |
|
|  |  |  |  |  |  |  |  |  |  | S |
| T | T |
|  |  |  |  |
|
|
|
|
| S |
|
|
|
| . | . | . |
|  |  |  |  |  |  |  | T |
|  |  |  |  |
|
| S |
| S | . | . | . | . | . | . | S |
|  |  |  |  |  |  |  |  |  | T | T | S | S |
|
| G | G | G |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | |
|
|
. | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 |
  |
  |   |
317 | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | |
340 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
I | A | H | R | G | S | F | E | S | F | A | Q | A | V | R | D | I | A | R | N | A | M | P | . |
G | K | V | L | L |
Query Conservation |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   | . |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|
|
Template Sequence |   |
V | T | H | R | F | P | L | E | D | A | L | K | A | F | E | T | A | S | D | P | K | T | G | A | I | K | V | Q | I |
Template Known Secondary structure |   |
 |  |  |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  |
| G | G | G |
|
| S |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
331 | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . |
  |