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Job DescriptionP28629
Confidence99.90%DateWed Jan 25 15:20:47 GMT 2012
Rank33Aligned Residues300
% Identity15%Templatec3e9kA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex
Resolution1.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   204.....210.........220. ........230.........240.... .....250.........260.. ....... 270.
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Query Sequence  TGAFGESEKYAARVFGAD. RSWSVVVGTSGSNRTIMQACMTD. . . NDVVVVDRNCHKSIEQGL. . . . MLTGAKP. . . . VY
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Template Sequence  ITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRM
Template Known Secondary structure  GGTTGGGT

GGG
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TT

TT

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   110.........120.........130.........140.........150.........160.........170.........180.........
 
   272.......280.........290.........300.........310.........320.... .....330.........340.........350
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Query Sequence  MVPSRNRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTNCTYD. GVCYNAKEAQDLLEKTSDRLHFDEAW
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Template Sequence  IKPREG. . . . . . . . . EETLRIEDILEVIEKEG. . . . . . . DSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAH
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SS

G.......GGSB
TTT
BB

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   190..... ....200.........210.. .......220.........230.........240.........250...
 
   351........360.........370.........380......... 390.........400.. .......
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Query Sequence  YGYARFNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLN. ALSQASYIHVREG. . . . . . . . . . . . . . . . . . . . RGAINFS
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Template Sequence  AVGNV. . . . . . ELYLHDWGVD. . . . . . . FACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKL
Template Known Secondary structure  TTTTS......


T

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SSSTT


TT



GGGTTTS

SS

GGGB
TT

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   254.... .260........ .270.........280.........290.........300.........310.........320
 
   410.........420.........430.........440.........450.........460.........470.........480.........
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Query Sequence  RFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTADGSWFFKPWNKEVVTDPQT
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Template Sequence  QLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGVVNIITPS. . . . . . . . . . . . . . .
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SSGGGG

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   321........330.........340.........350.........360.........370.........380.....
 
   490.........500.........510.........520.........530..... ....540.........550.........560.....
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Query Sequence  GKTYDFADAPTKLLTTVQDCWVMHPGESWHGFKDIPDNWSMLDPIK. . . . VSILAPGMGEDGELEETGVPAALVTAWLGR
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Template Conservation  ..........................................    
   
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HVEERGCQLTITFSVPN. . . . . . . . . . . . KDVFQELEK
Template Known Secondary structure  ..........................................SGGGB
S


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   395....400.........410. ........420
 
   566...570.........580.. .......590.........600.
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Query Sequence  HGIVPTRTTDFQIMFLF. SMGVTRGKWGTLVNTLCSF
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Template Sequence  RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSI
Template Known Secondary structure  TT
TTTB

TTT

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   421........430.........440.........450.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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