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Job DescriptionP28629
Confidence99.89%DateWed Jan 25 15:20:47 GMT 2012
Rank37Aligned Residues300
% Identity16%Templatec2hzpA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   209210.........220. ........230.........240.... .....250.........260.. ....... 270......
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Query Sequence  ESEKYAARVFGAD. RSWSVVVGTSGSNRTIMQACMTD. . . NDVVVVDRNCHKSIEQGL. . . . MLTGAKP. . . . VYMVPSR
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Template Conservation       

 
 

   

      
  
     
       

 

     


            
              
Template Sequence  SIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPRE
Template Known Secondary structure  TTGGGGT

GGG
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SSS
TT

TT




T
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   115....120.........130.........140.........150.........160.........170.........180.........190....
 
   277..280.........290.........300.........310.........320.... .....330.........340.........350.....
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Query Sequence  NRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTNCTYD. GVCYNAKEAQDLLEKTSDRLHFDEAWYGYAR
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Template Sequence  G. . . . . . . . . EETLRIEDILEVIEKEG. . . . . . . DSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNV
Template Known Secondary structure  T.........
SS

G.......GGSB
TTT
BB

TT

TTTTTTS
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   195 ....200.........210.. .......220.........230.........240.........250........
 
   356...360.........370.........380.........390.... .....400.. .......410....
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Query Sequence  FNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLNALSQA. SYIHVREG. . . . . . . . . . . . . . . . . . . . RGAINFSRFNQA
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Template Sequence  . . . . . . ELYLHDWGVD. . . . . . . FACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPG
Template Known Secondary structure  ......


T

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SSSTT


TT



GGGTTTS

SS

GGGB
TT

S


B
SS
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   259260........ .270.........280.........290.........300.........310.........320.....
 
   415....420.........430.........440.........450.........460.........470.........480.........490....
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Query Sequence  YMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTADGSWFFKPWNKEVVTDPQTGKTYD
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Template Sequence  VCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGK. . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  GGGG

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   326...330.........340.........350.........360.........370........
 
   495....500.........510.........520.........530.........540.........550.........560.........570....
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Query Sequence  FADAPTKLLTTVQDCWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVTAWLGRHGIVPTRTT
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . VVNIITPSHVEERGCQLTITFSVPN. . . . . . . . . . . . KDVFQELEKRGVVCDKRN
Template Known Secondary structure  .........................

S
SSGGGB
S


TT............

TTT
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   387..390.........400.........410. ........420.........
 
   575....580.. .......590.........600.
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Query Sequence  DFQIMFLF. SMGVTRGKWGTLVNTLCSF
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Template Sequence  PNGIRVAPVPLYNSFHDVYKFTNLLTSI
Template Known Secondary structure  TTB

TTT

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   430.........440.........450.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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