|   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | S | S | P | L | R | V | A | I | I | G | A | G | Q | V | A | D | K | V | H | A | S | Y | Y | C | T | R | N | D | L | E | L | V | A | V | C | D | S | R | L | S | Q | A | Q | A | L | A | E | K | Y | G | N | A | S | V | W | D | D | P | Q | A | M | L | L | A | V | K | P | D | V | V | S | V | C | S | P | N | R | F | H |
Query Conservation |   |
  |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|
|   |
|   |
|   |
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|
|
|   |
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |   |
|
Template Sequence |   |
T | R | K | P | L | R | A | A | I | I | G | L | G | R | L | G | E | R | H | A | R | H | L | V | N | K | I | Q | G | V | K | L | V | A | A | C | A | L | D | S | N | Q | L | E | W | A | K | N | E | L | G | V | E | T | T | Y | T | N | Y | K | D | X | I | D | T | E | N | I | D | A | I | F | I | V | A | P | T | P | F | H |
Template Known Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
| S | T | T |  |  |  |  |  |  |  |  |  |  | T |
| S | S |  |  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  | S |
|  |  |  |  |  | T | T | S |
|
| S |  |  |  |  |
| S |
| G | G | G |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
  |
  |   |
86 | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
. | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | E | H | T | L | M | A | L | E | A | G | C | H | V | M | C | E | K | P | P | A | M | T | P | E | Q | A | R | E | M | C | D | T | A | R | K | L | G | . |
K | V | L | A | Y | D | F | H | H | R | F | A | L | D | T | Q | Q | L | R | E | Q | V | T | N | G | V | L | G | E | I | Y | V | T | T | A | R | A | L | R | R | C |
Query Conservation |   |
  |   |   |   |   |   |
|
|   |   |
|
|   |
|   |   |
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   | . |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |
|
|
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | E | X | T | I | Y | A | X | N | A | G | L | N | V | F | C | E | K | P | L | G | L | D | F | N | E | V | D | E | X | A | K | V | I | K | S | H | P | N | Q | I | F | Q | S | G | F | X | R | R | Y | D | D | S | Y | R | Y | A | K | K | I | V | D | N | G | D | I | G | K | I | I | Y | X | R | G | Y | G | I | D | P | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
| S |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T | S |
|  |  |
|
|
| G | G | G | T |
|  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
| S |  |  |  |  |  |  |  |  |  |  |  | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
  |
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | P | G | W | G | V | F | T | N | K | E | L | Q | G | G | G | P | L | I | D | I | G | I | H | M | L | D | A | A | M | Y | V | L | G | F | P | A | V | K | S | V | N | A | H | S | F | Q | K | I | G | T | Q | K | S | C | G | Q | F | G | E | W | D | P | A | T | Y | S | V | E | D | S | L | F | G | T | I | E | F | H |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|   |
|   |
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|   |
|
|   |   |   |   |
|   |
| . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | G | X | E | S | F | T | K | F | A | T | E | A | D | S | G | G | I | F | V | D | X | N | I | H | D | I | D | L | I | R | W | F | T | G | . |
Q | D | P | V | Q | A | Y | G | L | T | S | N | I | A | A | P | Q | L | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | I | G | E | F | E | T | G | V | A | Q | L | K | X | S |
Template Known Secondary structure |   |
G | G |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  | S | . |
|
|  |  |  |  |  |  |  |  |  |
| S | S |
| G | G | G | G | . | . | . | . | . | . | . | . | . | . | G | G | T |
|
| S |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | |
. | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
  |
  |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | G | G | I | L | W | L | E | T | S | F | A | L | N | I | R | E | Q | S | I | M | N | V | S | F | C | G | D | K | A | G | A | T | L | F | P | A | H | I | Y | T | D | N | N | G | E | L | M | T | L | M | Q | R | E | I | A | D | D | . |
. |
. |
. |
. |
. |
N | R | H | L | R | S | M | E | A | F | I | N | H | V | Q | G |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
D | G | V | I | A | T | L | I | G | G | R | H | A | A | . |
. |
H | G | N | Q | V | E | L | E | V | X | G | S | N | G | W | V | R | I | G | E | H | P | D | L | N | R | V | T | V | F | N | D | Q | G | V | V | R | P | S | L | Q | S | F | G | E | R | F | D | T | A | F | T | D | E | V | Q | D | F | V | N | N | V | I | V |
Template Known Secondary structure |   |
T | S |
|  |  |  |  |  |  |  |  |  |  | S | . | . | S | S |
|  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |
| S | S |
| B |
| S | S |
|
|  |  |  | T | T |  |  |  |
|
| B |
|
|
|  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | |
|
. | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 |
  |
  |   |
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | P | V | M | I | A | D | A | E | Q | G | Y | I | I | Q | Q | L | V | A | A | L | Y | Q | S | A | E | T | G | T | R | V | E | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |
|
Template Sequence |   |
G | K | Q | P | E | V | T | V | D | D | G | I | K | A | L | K | I | A | K | A | C | Q | Q | S | A | N | I | G | K | L | V | D | I |
Template Known Secondary structure |   |
T |
|
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
311 | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . |
  |