Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	S	Q	I	Q	R	F	G	G	A	M	F	T	P	V	L	L	F	P	F	A	G	I	V	V	G	L	A	I	L	L	Q	N	P	M	F	V	G	E	S	L	T	D	P	N	S	L	F	A	Q	I	V	H	I	I	E	E	G	G
Secondary structure
SS confidence
Disorder		?	?	?																													?	?		?	?	?	?	?	?	?		?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		W	T	V	F	R	N	M	P	L	I	F	A	V	G	L	P	I	G	L	A	K	Q	A	Q	G	R	A	C	L	A	V	M	V	S	F	L	T	W	N	Y	F	I	N	A	M	G	M	T	W	G	S	Y	F	G	V	D	F	T	Q	D
Secondary structure
SS confidence
Disorder																						?	?																								?	?	?	?		?	?	?	?		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	V	A	G	S	G	L	T	M	M	A	G	I	K	T	L	D	T	S	I	I	G	A	I	I	I	S	G	I	V	T	A	L	H	N	R	L	F	D	K	K	L	P	V	F	L	G	I	F	Q	G	T	S	Y	V	V	I	I	A	F
Secondary structure
SS confidence
Disorder			?														?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	V	M	I	P	C	A	W	L	T	L	L	G	W	P	K	V	Q	M	G	I	E	S	L	Q	A	F	L	R	S	A	G	A	L	G	V	W	V	Y	T	F	L	E	R	I	L	I	P	T	G	L	H	H	F	I	Y	G	Q	F	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		F	G	P	A	A	V	E	G	G	I	Q	M	Y	W	A	Q	H	L	Q	E	F	S	L	S	A	E	P	L	K	S	L	F	P	E	G	G	F	A	L	H	G	N	S	K	I	F	G	A	V	G	I	S	L	A	M	Y	F	T	A	A
Secondary structure
SS confidence
Disorder																						?	?	?					?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		P	E	N	R	V	K	V	A	G	L	L	I	P	A	T	L	T	A	M	L	V	G	I	T	E	P	L	E	F	T	F	L	F	I	S	P	L	L	F	A	V	H	A	V	L	A	A	S	M	S	T	V	M	Y	L	F	G	V	V	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.
Sequence		N	M	G	G	G	L	I	D
Secondary structure
SS confidence
Disorder						?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3qnq chain D Region: 3 - 365 Aligned: 347 Modelled: 359 Confidence: 100.0% Identity: 15% PDB header:membrane protein, transport protein Chain: D: PDB Molecule:pts system, cellobiose-specific iic component; PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system Phyre2 PDB 1hgv chain A Region: 41 - 83 Aligned: 43 Modelled: 43 Confidence: 62.2% Identity: 14% PDB header:virus Chain: A: PDB Molecule:ph75 inovirus major coat protein; PDBTitle: filamentous bacteriophage ph75 Phyre2 PDB 1j9i chain A Region: 303 - 328 Aligned: 16 Modelled: 26 Confidence: 16.1% Identity: 25% Fold: Putative DNA-binding domain Superfamily: Putative DNA-binding domain Family: Terminase gpNU1 subunit domain Phyre2 1 c3qnqD_ 2 c1hgvA_ 3 d1j9ia_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3qnqD_ 100.0 15 PDB header:membrane protein, transport protein Chain: D: PDB Molecule:pts system, cellobiose-specific iic component; PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system 2 c1hgvA_ 62.2 14 PDB header:virus Chain: A: PDB Molecule:ph75 inovirus major coat protein; PDBTitle: filamentous bacteriophage ph75 3 d1j9ia_ 16.1 25 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:Terminase gpNU1 subunit domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0