|   |
11 | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | |
|
|
. | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | |
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
S | G | A | K | Q | V | L | Q | E | T | F | G | Y | Q | Q | F | R | P | G | Q | E | E | I | I | D | T | V | L | S | G | R | D | C | L | V | V | M | P | T | G | G | G | K | S | L | C | Y | Q | I | P | A | L | L | . |
. |
. |
L | N | G | L | T | V | V | V | S | P | L | I | S | L | M | K | D | Q | V | D | Q | L | . |
. |
Query Conservation |   |
  |   |   |   |   |   |
|
|   |   |
|
|   |   |   |
|
|
|   |
|   |
|
|
|   |   |
|
|   |
|   |
|
|
|
|   |   |
|
|
|
|
|
|
|
|   |
|   |
|
|
|
|   | . | . | . |   |   |   |   |   |
|
|
|
|
|
|   |
|
|   |   |
|
|
|   |   |
| . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
|   |
|
|
|
|   |   |
|   |
|
|   |
|   |   | . |
|
|
|
|
|
|
|   |   |
|
|   |
|   | . | . |
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |
|   |   |
Template Sequence |   |
A | L | T | R | E | S | A | K | R | Y | L | G | M | R | H | F | . |
D | V | Q | L | I | G | G | A | V | L | H | E | G | K | . |
. |
I | A | E | M | K | T | G | E | G | K | T | L | V | A | T | L | A | V | A | L | N | A | L | T | G | K | G | V | H | V | V | T | V | N | D | Y | L | A | R | R | D | A | E | W | M | G | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  | T | T | S | . | . |  |  |  |
|
| S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |
|
|  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
66 | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | |
. | . | . | . | . | . | . | . | 90 | . | . | . | . | . | |
|
. | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . |
  |
  |   |
|
|
86 | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | 140 | . | . | . | . | . | . | . | . | . | 150 | . | |
|
Predicted Secondary structure |   |
. | . |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|  |  |  | . | . |
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
. |
. |
Q | A | N | G | V | A | A | A | C | L | N | S | T | Q | T | R | E | Q | Q | L | E | V | M | T | G | C | R | T | G | Q | I | R | L | L | Y | I | A | P | E | R | L | M | L | D | N | F | L | E | H | L | A | H | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | P | V | L | L | A | V | D | E | A | H | C | I | . |
. |
Query Conservation |   |
. | . |   |   |   |
|
|   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . |   |
|   |
|
|
|
|
|
|
|
|   |
| . | . |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
|
|   |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |
|
|
|   |
|
|   | . | . | . | . | . | . |   |
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
Template Sequence |   |
V | Y | R | G | L | G | L | S | V | G | V | I | Q | H | A | S | T | P | A | E | R | R | K | A | Y | L | . |
. |
. |
. |
. |
. |
A | D | V | T | Y | V | T | N | S | E | L | G | F | D | Y | L | R | D | N | M | A | I | S | P | D | Q | L | V | L | R | H | D | H | P | L | H | Y | A | I | I | D | E | V | D | S | I | L | I |
Template Known Secondary structure |   |
 |  |  | T | T | T |
|
|  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S | T | T | T |
|
| S |
| S | S | S | S | S |
|  |  |  |  | T | T |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |
|   |
|
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |
Template Sequence |   |
D | E | A | R | T | P | L | I | I | S | G | P | A | E | K | A | T | D | L | Y | Y | K | M | A | E | I | A | K | K | L | E | R | G | L | P | A | E | P | G | V | R | K | E | P | T | G | D | Y | T | V | E | E | K | N | R | S | V | H | L | T | L | Q | G | I | A | K | A | E | K | L | L | G | I | E | G | L | F | S | P | E |
Template Known Secondary structure |   |
S | S | T | T | S |
|  |  |  |  |  | S |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
|
|
| S | S | S |
|
|
| S | S |
|
|
|
|
| T | T | S |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  | T | T | T |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
152 | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | Q | W | G | H | D | F | R | P | E | Y | A | A | L | G | Q | L | R | Q | R | F | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|   |   |   |
|   |   |
|
|   |
|   |   |
|   |   |   |
|
|
|
|
|
|   |
|
|   |
|   |
|
|
|
|   |
|
|
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|
|   |
|
|
|
|
|
|   |
|
|   |
|
|
Template Sequence |   |
N | M | E | L | A | H | M | L | I | Q | A | I | R | A | K | E | L | Y | H | R | D | R | D | Y | I | V | Q | D | G | Q | V | I | I | V | D | E | F | T | G | R | L | M | P | G | R | R | Y | G | E | G | L | H | Q | A | I | E | A | K | E | G | V | R | I | E | R | E | N | Q | T | L | A | T | I | T | Y | Q | N | F | F | R |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  | T | T | T | T |  |  |
| T | T |
|
|
| G | G | G |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
| S |
|  |  |  |  |  |  |
|  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
297 | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . |
  |
  |   |
|
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | |
|
. | . | . | . | . | 240 | . | . | . | . | . |
Predicted Secondary structure |   |
. |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
T | L | P | F | M | A | L | T | A | T | A | D | D | T | T | R | Q | D | I | V | R | L | L | G | L | N | D | P | L | I | Q | I | S | S | F | D | R | P | N | I | R | Y | M | L | . |
. |
. |
. |
. |
M | E | K | F | K | P | L | D | Q | L | M | R | Y | V | Q | E | Q | . |
. |
R | G | K | S | G | I | I | Y | C | N | S |
Query Conservation |   |
. |   |   |   |
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |   |   | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   | . | . |   |   |   |   |   |
|
|
|
|   |
|
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|   |
|
|
|
|
|
|   |
| . |
|   |   |
|
|   |   |
|
|   |
|   | . | . | . |
|
|   |
|
|
|
|
|
|   |   |
|   |
|   |
|
|   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|
Template Sequence |   |
L | Y | E | K | R | A | G | M | T | G | T | A | K | T | . |
E | E | K | E | F | Q | E | I | Y | G | M | D | . |
. |
. |
V | V | V | V | P | T | N | R | P | V | I | R | K | D | F | P | D | V | V | Y | R | T | E | K | G | K | F | Y | A | V | V | E | E | I | A | E | K | Y | E | R | G | Q | P | V | L | V | G | T | I | S |
Template Known Secondary structure |   |
T | S | S |  |  |  |  |  |  | S | S |
| G | G | . | G |  |  |  |  |  |  |  |  |
|
|
| . | . | . |  |  |  |
|
|
| S | S |
|
|
|
|  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
| S | S |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|  |  |  | . |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
377 | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | |
. | . | . | . | . | . | . | . | . | 400 | . | . | |
|
|
. | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . |
  |
  |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
R | A | K | V | E | D | T | A | A | R | L | Q | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|   |   |   |
|   |
|
|   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|   |
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | E | K | S | E | R | L | S | Q | M | L | K | E | P | R | L | Y | L | P | R | L | E | M | R | L | E | L | F | K | K | A | S | Q | K | Q | Q | G | P | E | W | E | R | L | R | K | L | L | E | R | P | A | Q | L | K | D | E | D | L | A | P | F | E | G | L | I | P | P | K | G | N | L | R | T | A | W | E | G | L | K | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | S | S | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  |  |  |  |  | T | S | S | S | T | T |
| S |  |  |  |  | S | G | G | G | G | G |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
453 | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | G | I | S | A | A | A | Y | H | A | G | L | E | N | N | V | R | A | D | V | Q | E | K | F | Q | R | D | D | L | Q | I | V | V | A | T | V | A | F | G | M | G | I | N | K | P | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . | . |   |
|
|   |
|   |   |
|
|
|   |
|   |   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|
|
|   |
|   |
|   |
|
|
|   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |   |   |
|
|
|
|
|
|
|
|
|   |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | V | H | T | L | A | V | L | R | Q | G | I | P | H | Q | V | L | N | A | K | H | H | A | R | E | A | E | I | V | A | Q | A | G | R | S | K | T | . |
. |
V | T | I | A | T | N | M | A | G | R | G | T | D | I | K | L | G | G | N | P | E | Y | L | A | A | A | L | L | E | K | E | G | F | D | R | Y | E | W | K | V | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T |
|
|
|
|
|  |  |
| S | S | S |  |  |  |  |  |  |  |  |  | T | T | T | S | T | T |
| . | . |  |  |  |  |
| S | S | T | T | T | T |
|
|
|
| S | S |
|
|  |  |  |  |  | T | T | T | T | S | S | S |
| S | T | T | T |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
533 | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | |
|
570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
305 | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | R | F | V | V | H | F | D | I | P | R | N | I | E | S | Y | Y | Q | E | T | G | R | A | G | R | D | G | L | P | A | E |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |
|
|   |   |   |   |
|   |
|   |
|   |
|   |
|   |   |
|
|
|
|
|
|
|   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Sequence |   |
L | F | I | K | K | M | V | A | G | K | E | E | E | A | R | A | L | A | Q | E | L | G | I | R | E | E | L | L | E | R | I | R | E | I | R | E | E | C | K | Q | D | E | E | R | V | R | A | L | G | G | L | F | I | I | G | T | E | R | H | E | S | R | R | I | D | N | Q | L | R | G | R | A | G | R | Q | G | D | P | G | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|
|
|  |  |  | S | S |
|
| S | S |  |  |  |  |  |  |  |  |  | T | S | S |
| S | S |
|
|
|  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
611 | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 |
  |
  |   |
336 | . | . | . | 340 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | |
. | 380 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | M | L | F | Y | D | P | A | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | A | W | L | R | R | C | L | E | E | K | P | Q | G | Q | L | Q | D | I | E | R | H | K | L | N | A | M | G | A | F | A | E | A | Q | . |
T | C | R | R | L | V | L | L | N | Y |
Query Conservation |   |
  |   |
|
|   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . |   |
|
|
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |   |   |
|
|   |
|   |   |
|
Template Sequence |   |
S | R | F | Y | V | S | F | D | D | D | L | M | R | L | F | A | S | D | R | V | I | A | M | L | D | R | M | G | F | D | D | S | E | P | I | E | H | P | M | V | T | R | S | I | E | R | A | Q | K | R | V | E | D | R | N | F | A | I | R | K | Q | L | L | Q | F |
Template Known Secondary structure |   |
 |  |  |  |  |  | S | S | S |  |  |  |  |  | S | S |
| T | T |  |  |  |  |  |  |  | T |
|
|
| S | S | S |
| B |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
691 | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . |
  |