|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 70 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Q | A | E | V | L | N | L | E | S | G | A | K | Q | V | L | Q | E | T | F | G | Y | Q | Q | F | R | P | G | Q | E | E | I | I | D | T | V | L | S | G | R | . |
D | C | L | V | V | M | P | T | G | G | G | K | S | L | C | Y | Q | I | P | A | L | L | . |
. |
. |
. |
. |
L | N | G | L | T | V | V | V | S | P | L | I |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |
|
|
|   |
|   |
|
|
|   |   |
|
|   |
|   | . |
|
|
|
|   |   |
|
|
|
|
|
|
|
|   |
|   |
|
|
|
|   | . | . | . | . | . |   |   |   |   |   |
|
|
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   | . |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
Template Sequence |   |
X | N | F | N | E | L | N | L | S | D | N | I | L | N | A | I | R | N | . |
K | G | F | E | K | P | T | D | I | Q | X | K | V | I | P | L | F | L | N | D | E | Y | N | I | V | A | Q | A | R | T | G | S | G | K | T | A | S | F | A | I | P | L | I | E | L | V | N | E | N | N | G | I | E | A | I | I | L | T | P | T | R |
Template Known Secondary structure |   |
S | S | G | G | G | S | S |
|
|  |  |  |  |  |  |  |  |  | . |  | T |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  |
|
| S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  | S |
| S | S | S | S |
|
|  |  |  |  |
| S |
|  |
Template Predicted Secondary structure |   |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | |
. | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | |
|
|
|
. | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | L | M | K | D | Q | V | D | Q | L | Q | A | N | . |
. |
. |
. |
G | V | A | A | A | C | L | N | S | T | Q | T | R | E | Q | Q | L | E | V | M | T | G | C | R | T | G | Q | I | R | L | L | Y | I | A | P | E | R | L | M | L | D | N | F | L | E | H | L | A | H | W | N | P | V | L | L | A | V | D | E | A | H | C | I |
Query Conservation |   |
|
|   |   |
|
|
|   |   |
|   |   |   | . | . | . | . |
|
|   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | L | A | I | Q | V | A | D | E | I | E | S | L | K | G | N | K | N | L | K | I | A | K | I | Y | G | G | K | A | I | Y | P | Q | I | K | A | L | K | . |
. |
. |
. |
. |
N | A | N | I | V | V | G | T | P | G | R | I | L | D | H | I | N | R | G | T | L | N | L | K | N | V | K | Y | F | I | L | D | E | A | D | E | X |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|
|
|  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | T |
| S |  |  |  |  |
|  |  |  |  |  |  |  |  |  | T | T | S | S |
| G | G | G |
|
|  |  |  |  |  | T |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
  |
  |   |
152 | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | Q | W | G | H | D | F | R | P | E | Y | A | A | L | G | Q | L | R | Q | R | F | P | T | L | P | F | M | A | L | T | A | T | A | D | D | T | T | R | Q | D | I | V | R | L | L | G | L | N | D | P | L | I | Q | I | S | S | F | D | R | P | N | I | R | Y | M | L | M | E | K | F | K | P | L | D | Q | L | M | R | Y | V |
Query Conservation |   |
  |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | N | X | G | F | I | K | D | V | . |
. |
. |
. |
E | K | I | L | N | A | C | N | K | D | K | R | I | L | L | F | S | A | T | X | P | R | E | I | L | N | L | A | K | K | Y | X | G | . |
. |
D | Y | S | F | I | K | A | K | I | N | A | N | I | E | Q | S | Y | V | E | V | N | E | N | E | R | F | E | A | L | C | R | L |
Template Known Secondary structure |   |
 | T | T | T | T |  |  |  |  | . | . | . | . |  |  |  |  |  | T | S |
| S | S |
|  |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . | S |  |  |  |  |  |
|
| S | T | T | T | S |  |  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | |
|
|
|
. | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | |
|
. | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . |
  |
  |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | E | Q | R | G | K | S | G | I | I | Y | C | N | S | R | A | K | V | E | D | T | A | A | R | L | Q | S | K | G | I | S | A | A | A | Y | H | A | G | L | E | N | N | V | R | A | D | V | Q | E | K | F | Q | R | D | D | L | Q | I | V | V | A | T | V | A | F | G | M | G | I | N | K | P | N | V | R | F | V | V | H | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |   |
|   |
|
|   |   |
|   |   |   |
|
|   |
|   |   |
|
|
|   |
|   |   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|
|
|   |
|   |
|   |
|
|
|   |
|
|
|
|   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |   |
|   |   |
|
|
|
|
|   |
|   |   |
|
|   |   |
Template Sequence |   |
L | K | N | K | E | F | Y | G | L | V | F | C | K | T | K | R | D | T | K | E | L | A | S | X | L | R | D | I | G | F | K | A | G | A | I | H | G | D | L | S | Q | S | Q | R | E | K | V | I | R | L | F | K | Q | K | K | I | R | I | L | I | A | T | D | V | X | S | R | G | I | D | V | N | D | L | N | C | V | I | N | Y |
Template Known Secondary structure |   |
 |
| S | T | T |
|
|  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|
|  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S | S |  |  |  |  |
| T | T |  |  |  |  |
|
|
| S |
|
| S |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
234 | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . |
  |
  |   |
312 | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | I | P | R | N | I | E | S | Y | Y | Q | E | T | G | R | A | G | R | D | G | L | P | A | E | A | M | L | F | Y | D | P | A | D | M | A | W | L | R | R | C | L | E |
Query Conservation |   |
  |   |
|   |
|   |
|   |
|   |
|   |   |
|
|
|
|
|
|
|   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |
|
|   |
|
|
|
|
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |
Template Sequence |   |
H | L | P | Q | N | P | E | S | Y | X | H | R | I | G | R | T | G | R | A | G | K | K | G | K | A | I | S | I | I | N | R | R | E | Y | K | K | L | R | Y | I | E | R |
Template Known Secondary structure |   |
S |
|
| S | S |  |  |  |  |  |  |  | S | T | T | T |
|
| T | T | S |
|
|  |  |  |  |  |  |  | S | T | T |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
314 | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . |
  |